The high heterogeneity of obsessive-compulsive disorder is best described by a multidimensional model involving symptom dimensions. Our study aimed at investigating white matter alterations associated with obsessive-compulsive disorder focusing on the impact of long lasting effect of symptom dimensions assessed at onset of the illness. Furthermore, we investigate white matter alterations associated with this disorder controlling for the impact of medications and for the prevailing current symptom dimension.

White matter alterations associate with onset symptom dimension in obsessive-compulsive disorder / Bollettini, Irene; Mazza, Mario Gennaro; Muzzarelli, Laura; Dallaspezia, Sara; Poletti, Sara; Vai, Benedetta; Smeraldi, Enrico; Benedetti, Francesco. - In: PSYCHIATRY AND CLINICAL NEUROSCIENCES. - ISSN 1323-1316. - (2017). [Epub ahead of print] [10.1111/pcn.12563]

White matter alterations associate with onset symptom dimension in obsessive-compulsive disorder

POLETTI, SARA;SMERALDI, ENRICO
Penultimo
;
Benedetti, Francesco
2017-01-01

Abstract

The high heterogeneity of obsessive-compulsive disorder is best described by a multidimensional model involving symptom dimensions. Our study aimed at investigating white matter alterations associated with obsessive-compulsive disorder focusing on the impact of long lasting effect of symptom dimensions assessed at onset of the illness. Furthermore, we investigate white matter alterations associated with this disorder controlling for the impact of medications and for the prevailing current symptom dimension.
2017
Diffusion Tensor Imaging; Endophenotype; Myelin Sheath; Obsessive-Compulsive Disorder; Treatment
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/61144
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