Aim: The safety, feasibility and oncological results of laparoscopic resection for advanced colon cancer were evaluated. Method: Seventy consecutive patients with a histologically proven T4 colon cancer who underwent laparoscopic (LPS) right or left colectomy were matched for comorbidity on admission (American Society of Anesthesiologists score), tumour stage and grading with 70 patients who underwent open colectomy over a 10-year period. Short- and long-term outcome measures were evaluated. Results: The overall conversion rate was 7.1%. Less intra-operative blood loss (P = 0.01), a trend toward a longer operation time (P = 0.09) and a lower peri-operative blood transfusion rate (P = 0.06) were observed in the LPS group. A similar number of lymph nodes were retrieved (P = 0.37) and the R1 resection rate (P = 0.51) was no different in the two groups. The overall mortality rate was 1.4%. The overall morbidity rate was 21.4% (15/70 patients) in the LPS group and 27.5% (19/70 patients) in the open group (P = 0.42), with anastomotic leakage rates of 7.1% and 4.2% (P = 0.32). Length of stay was shorter after LPS (P = 0.009). Five-year overall survival rate (P = 0.18) and disease-free survival rate (P = 0.20) did not differ significantly between the two groups. Conclusion: Laparoscopic treatment of T4 colon cancer is safe and feasible and provides a similar surgical and oncological outcome compared with the open technique. © 2013 The Association of Coloproctology of Great Britain and Ireland.

Laparoscopic treatment of advanced colonic cancer: A case-matched control with open surgery / Vignali, Andrea; Ghirardelli, L.; Di Palo, S.; Orsenigo, E.; Staudacher, Carlo. - In: COLORECTAL DISEASE. - ISSN 1462-8910. - 15:8(2013), pp. 944-948. [10.1111/codi.12170]

Laparoscopic treatment of advanced colonic cancer: A case-matched control with open surgery

VIGNALI, ANDREA
Primo
;
STAUDACHER, CARLO
Ultimo
2013-01-01

Abstract

Aim: The safety, feasibility and oncological results of laparoscopic resection for advanced colon cancer were evaluated. Method: Seventy consecutive patients with a histologically proven T4 colon cancer who underwent laparoscopic (LPS) right or left colectomy were matched for comorbidity on admission (American Society of Anesthesiologists score), tumour stage and grading with 70 patients who underwent open colectomy over a 10-year period. Short- and long-term outcome measures were evaluated. Results: The overall conversion rate was 7.1%. Less intra-operative blood loss (P = 0.01), a trend toward a longer operation time (P = 0.09) and a lower peri-operative blood transfusion rate (P = 0.06) were observed in the LPS group. A similar number of lymph nodes were retrieved (P = 0.37) and the R1 resection rate (P = 0.51) was no different in the two groups. The overall mortality rate was 1.4%. The overall morbidity rate was 21.4% (15/70 patients) in the LPS group and 27.5% (19/70 patients) in the open group (P = 0.42), with anastomotic leakage rates of 7.1% and 4.2% (P = 0.32). Length of stay was shorter after LPS (P = 0.009). Five-year overall survival rate (P = 0.18) and disease-free survival rate (P = 0.20) did not differ significantly between the two groups. Conclusion: Laparoscopic treatment of T4 colon cancer is safe and feasible and provides a similar surgical and oncological outcome compared with the open technique. © 2013 The Association of Coloproctology of Great Britain and Ireland.
2013
Laparoscopy; Multivisceral resection; Oncological results; T4 colon cancer; Aged; Anastomotic Leak; Blood Loss, Surgical; Blood Transfusion; Colectomy; Colonic Neoplasms; Disease-Free Survival; Feasibility Studies; Female; Humans; Kaplan-Meier Estimate; Laparoscopy; Length of Stay; Male; Middle Aged; Neoplasm Staging; Retrospective Studies; Survival Rate; Treatment Outcome; Gastroenterology
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/61220
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 60
  • ???jsp.display-item.citation.isi??? 61
social impact