A 57 year-old man underwent MRI with dynamic susceptibility contrast and dynamic contrast-enhanced perfusion for neurological symptoms suggesting the diagnosis of high-grade glioma. A F-FAZA PET/CT was performed because of the enrollment in a prospective clinical trial. Subsequent radiotherapy treatment has been planned based on conventional imaging; moreover, a F-FAZA PET/CT-guided treatment planning highlighting hypoxic regions has been simulated. After radiotherapy treatment, the man underwent MRI and F-FAZA PET/CT, showing partial response.
18F-FAZA PET/CT Hypoxia Imaging of High-Grade Glioma Before and After Radiotherapy / Mapelli, Paola; Zerbetto, Flavia; Incerti, Elena; Conte, Gian Marco; Bettinardi, Valentino; Fallanca, Federico; Anzalone, Nicoletta; Di Muzio, Nadia; Gianolli, Luigi; Picchio, Maria. - In: CLINICAL NUCLEAR MEDICINE. - ISSN 0363-9762. - 42:12(2017), pp. e525-e526-e526. [10.1097/RLU.0000000000001850]