Despite significant technical advancements in the design and manufacture of Left Ventricular Assist Devices, post-implant thrombotic and thromboembolic complications continue to affect long-term outcomes. Previous efforts, aimed at optimizing pump design as a means of reducing supraphysiologic shear stresses generated within the pump and associated prothrombotic shear-mediated platelet injury, have only partially altered the device hemocompatibility.

Blood damage in Left Ventricular Assist Devices: Pump thrombosis or system thrombosis?

Pappalardo, Federico
Penultimo
;
Consolo, Filippo
Ultimo
2019-01-01

Abstract

Despite significant technical advancements in the design and manufacture of Left Ventricular Assist Devices, post-implant thrombotic and thromboembolic complications continue to affect long-term outcomes. Previous efforts, aimed at optimizing pump design as a means of reducing supraphysiologic shear stresses generated within the pump and associated prothrombotic shear-mediated platelet injury, have only partially altered the device hemocompatibility.
2019
Inglese
189
194
6
Pubblicato
Left Ventricular Assist Device; hemodynamics; platelet activation; shear stress; thrombosis
UNISR.MED
OSR
none
13
info:eu-repo/semantics/article
262
Selmi, Matteo; Chiu, Wei-Che; Chivukula, Venkat Keshav; Melisurgo, Giulio; Beckman, Jennifer Ann; Mahr, Claudius; Aliseda, Alberto; Votta, Emiliano; R...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/84612
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