Reduced circulating and tissue carnitine levels, possibly leading to impaired mitochondrial function, have been postulated to be involved in the pathogenesis of insulin resistance. However, whether L-carnitine administration may improve insulin sensitivity in patients with impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM-2) is still controversial. The aim of the study was to explore the role of L-carnitine supplementation in influencing insulin sensitivity.

Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism / Molfino, A; Cascino, A; Conte, C; Ramaccini, C; Rossi Fanelli, F; Laviano, A. - In: JPEN. JOURNAL OF PARENTERAL AND ENTERAL NUTRITION. - ISSN 0148-6071. - 34:3(2010), pp. 295-299. [10.1177/0148607109353440]

Caloric restriction and L-carnitine administration improves insulin sensitivity in patients with impaired glucose metabolism

CONTE C;
2010-01-01

Abstract

Reduced circulating and tissue carnitine levels, possibly leading to impaired mitochondrial function, have been postulated to be involved in the pathogenesis of insulin resistance. However, whether L-carnitine administration may improve insulin sensitivity in patients with impaired fasting glucose (IFG) or type 2 diabetes mellitus (DM-2) is still controversial. The aim of the study was to explore the role of L-carnitine supplementation in influencing insulin sensitivity.
2010
Caloric Restriction; Insulin Resistance; Aged; Aged; 80 and over; Blood Glucose; Carnitine; Diabetes Mellitus; Type 2; Female; Glucose Intolerance; Glucose Metabolism Disorders; Glucose Tolerance Test; Humans; Insulin; Male; Middle Aged
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/86315
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 51
  • ???jsp.display-item.citation.isi??? 44
social impact