IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis because of the T cells and macrophages that invade the synovial fluid. These finding support a role for IL-18 in inflammation, allergy and immune diseases.

Impact of IL-18 on inflammation / Domenico, Tripodi; Anogeianaki, Antonia; Castellani Maria, Luisa; Felaco, Paolo; Toniato, E; De Lutiis, M. A.; Fulcheri, M; Tete', Stefano; Salini, Vincenzo; Frydas, I; Sabatino, Giuseppe; Shaik-Dasthagirisaheb, Y. B.. - In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. - ISSN 0393-974X. - 25:1(2011), pp. 7-11.

Impact of IL-18 on inflammation

Salini Vincenzo;
2011-01-01

Abstract

IL-18 is produced by many cell types, such as Kupffer cells, keratinocytes, macrophages, dendritic cells, and activated T cells stimulated by LPS. It is an important regulator of both innate and acquired immune responses. IL-18 plays a central role in rheumatoid arthritis because of the T cells and macrophages that invade the synovial fluid. These finding support a role for IL-18 in inflammation, allergy and immune diseases.
2011
Autoimmunity; Immunoregulation; Inflammation; Interleukin-18; Lymphocytes
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/87035
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 8
  • ???jsp.display-item.citation.isi??? 8
social impact