Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.

IL-36 a new member of the IL-1 family cytokines / Tripodi, D., Conti, F., Rosati, M., Maccauro, G., Saggini, A., Cianchetti, E., Angelucci, D., Fulcheri, M., Tetè, S., Salini, V., Caraffa, A., Antinolfi, P., Toniato, E., Castellani, M.l., Conti, P., Theoharides, Tc.. - In: JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS. - ISSN 0393-974X. - 26:1(2012), pp. 7-14.

IL-36 a new member of the IL-1 family cytokines

Salini V;
2012-01-01

Abstract

Interleukin-36 (IL-36) is a pro-inflammatory cytokine which plays an important role in innate and adaptive immunity. IL-36 activates MAPK and NF-kB pathways and is produced by many different cells. This cytokine is a family member of interleukin-1 (IL-1) and plays an important role in the pathophysiology of several diseases. Here we summarise and review the new aspects of this important pro-inflammatory cytokine.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/87094
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