A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality

Sartini, Chiara; Lomivorotov, Vladimir; Pisano, Antonio; Riha, Hynek; Baiardo Redaelli, Martina; Lopez-Delgado, Juan Carlos; Pieri, Marina; Hajjar, Ludhmila; Fominskiy, Evgeny; Likhvantsev, Valery; Cabrini, Luca; Bradic, Nikola; Avancini, Daniele; Wang, Chew Yin; Lembo, Rosalba; Novikov, Maxim; Paternoster, Gianluca; Gazivoda, Gordana; Alvaro, Gabriele; Roasio, Agostino; Wang, Chengbin; Severi, Luca; Pasin, Laura; Mura, Paolo; Musu, Mario; Silvetti, Simona; Votta, Carmine Domenico; Belletti, Alessandro; Corradi, Francesco; Brusasco, Claudia; Tamà, Simona; Ruggeri, Laura; Yong, Chow-Yen; Pasero, Daniela; Mancino, Giuseppe; Spadaro, Savino; Conte, Massimiliano; Lobreglio, Rosetta; Di Fraja, Diana; Saporito, Emanuela; D'Amico, Alessandro; Sardo, Salvatore; Ortalda, Alessandro; Yavorovskiy, Andrey; Riefolo, Claudio; Monaco, Fabrizio; Bellomo, Rinaldo; Zangrillo, Alberto; Landoni, Giovanni

doi:10.1053/j.jvca.2019.03.022

Reducing mortality is a key target in critical care and perioperative medicine. The authors aimed to identify all nonsurgical interventions (drugs, techniques, strategies) shown by randomized trials to increase mortality in these clinical settings.

A Systematic Review and International Web-Based Survey of Randomized Controlled Trials in the Perioperative and Critical Care Setting: Interventions Increasing Mortality / Sartini, Chiara; Lomivorotov, Vladimir; Pisano, Antonio; Riha, Hynek; Baiardo Redaelli, Martina; Lopez-Delgado, Juan Carlos; Pieri, Marina; Hajjar, Ludhmila; Fominskiy, Evgeny; Likhvantsev, Valery; Cabrini, Luca; Bradic, Nikola; Avancini, Daniele; Wang, Chew Yin; Lembo, Rosalba; Novikov, Maxim; Paternoster, Gianluca; Gazivoda, Gordana; Alvaro, Gabriele; Roasio, Agostino; Wang, Chengbin; Severi, Luca; Pasin, Laura; Mura, Paolo; Musu, Mario; Silvetti, Simona; Votta, Carmine Domenico; Belletti, Alessandro; Corradi, Francesco; Brusasco, Claudia; Tamà, Simona; Ruggeri, Laura; Yong, Chow-Yen; Pasero, Daniela; Mancino, Giuseppe; Spadaro, Savino; Conte, Massimiliano; Lobreglio, Rosetta; Di Fraja, Diana; Saporito, Emanuela; D'Amico, Alessandro; Sardo, Salvatore; Ortalda, Alessandro; Yavorovskiy, Andrey; Riefolo, Claudio; Monaco, Fabrizio; Bellomo, Rinaldo; Zangrillo, Alberto; Landoni, Giovanni. - In: JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA. - ISSN 1053-0770. - 33:10(2019), pp. 2685-2694. [10.1053/j.jvca.2019.03.022]