The implementation of spatial-covariance [18F]fluorodeoxyglucose positron emission tomography-based disease-related metabolic brain patterns as biomarkers has been hampered by intercenter imaging differences. Within the scope of the JPND-PETMETPAT working group, we illustrate the impact of these differences on Parkinson's disease-related pattern (PDRP) expression scores.

Factors affecting the harmonization of disease-related metabolic brain pattern expression quantification in [18F]FDG-PET (PETMETPAT) / Kogan, R. V.; de Jong, B. A.; Renken, R. J.; Meles, S. K.; van Snick, P. J. H.; Golla, S.; Rijnsdorp, S.; Perani, D.; Leenders, K. L.; Boellaard, R.. - In: ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING. - ISSN 2352-8729. - 11:1(2019), pp. 472-482. [10.1016/j.dadm.2019.04.002]

Factors affecting the harmonization of disease-related metabolic brain pattern expression quantification in [18F]FDG-PET (PETMETPAT)

Perani D.;
2019-01-01

Abstract

The implementation of spatial-covariance [18F]fluorodeoxyglucose positron emission tomography-based disease-related metabolic brain patterns as biomarkers has been hampered by intercenter imaging differences. Within the scope of the JPND-PETMETPAT working group, we illustrate the impact of these differences on Parkinson's disease-related pattern (PDRP) expression scores.
2019
FDG-PET; Harmonization; Hoffman 3D brain phantom; Neuroimaging biomarker; Principal component analysis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/94529
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