Epinephrine is frequently used as an inotropic and vasopressor agent in critically ill patients requiring hemodynamic support. Data from observational trials suggested that epinephrine use is associated with a worse outcome as compared with other adrenergic and nonadrenergic vasoactive drugs. We performed a systematic review and meta-analysis of randomized controlled trials to investigate the effect of epinephrine administration on outcome of critically ill patients.
Effect of Continuous Epinephrine Infusion on Survival in Critically Ill Patients. A Meta-Analysis of Randomized Trials / Belletti, Alessandro; Nagy, Adam; Sartorelli, Marianna; Mucchetti, Marta; Putzu, Alessandro; Sartini, Chiara; Morselli, Federica; De Domenico, Pierfrancesco; Zangrillo, Alberto; Landoni, Giovanni; Lembo, Rosalba. - In: CRITICAL CARE MEDICINE. - ISSN 0090-3493. - 48:3(2020), pp. 398-405. [10.1097/CCM.0000000000004127]
Effect of Continuous Epinephrine Infusion on Survival in Critically Ill Patients. A Meta-Analysis of Randomized Trials
De Domenico, Pierfrancesco;Zangrillo, Alberto;Landoni, GiovanniPenultimo
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2020-01-01
Abstract
Epinephrine is frequently used as an inotropic and vasopressor agent in critically ill patients requiring hemodynamic support. Data from observational trials suggested that epinephrine use is associated with a worse outcome as compared with other adrenergic and nonadrenergic vasoactive drugs. We performed a systematic review and meta-analysis of randomized controlled trials to investigate the effect of epinephrine administration on outcome of critically ill patients.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
