Immunoglobulin G4-related disease (IgG4-RD) promptly responds to glucocorticoids but relapses in a considerable fraction of patients. Reliable biomarkers of flare are currently lacking because the pathophysiology of IgG4-RD remains largely elusive. In the present work, we aimed to identify perturbations of B-cell subpopulations that might predict IgG4-RD relapse.
Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse / Lanzillotta, M.; Dellatorre, E.; Milani, R.; Bozzolo, E.; Bozzalla-Cassion, E.; Rovati, L.; Arcidiacono, P. G.; Partelli, S.; Falconi, M.; Ciceri, F.; Dagna, L.; DELLA TORRE, Emanuel. - In: ARTHRITIS RESEARCH & THERAPY. - ISSN 1478-6354. - 20:1(2018), p. 222. [10.1186/s13075-018-1718-5]
Increase of circulating memory B cells after glucocorticoid-induced remission identifies patients at risk of IgG4-related disease relapse
Lanzillotta M.;Arcidiacono P.G.;Partelli S.;Falconi M.;DELLA TORRE , EMANUEL
2018-01-01
Abstract
Immunoglobulin G4-related disease (IgG4-RD) promptly responds to glucocorticoids but relapses in a considerable fraction of patients. Reliable biomarkers of flare are currently lacking because the pathophysiology of IgG4-RD remains largely elusive. In the present work, we aimed to identify perturbations of B-cell subpopulations that might predict IgG4-RD relapse.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
