Glucocorticoids induce prompt clinical improvement in patients with IgG4-related disease (IgG4-RD) but their mechanisms of action in this specific condition are not fully understood. B lymphocytes appear central to IgG4-RD pathogenesis because B-cell depletion with rituximab leads to swift clinical responses. In the present work we aim to assess the effects of glucocorticoids on B-cell subpopulations in patients with IgG4-RD.
Effects of glucocorticoids on B-cell subpopulations in patients with IgG4-related disease / Lanzillotta, M., Della-Torre, E., Milani, R., Bozzolo, E., Bozzalla-Cassione, E., Rovati, L., Arcidiacono, P.G., Partelli, S., Falconi, M., Ciceri, F., Dagna, L.. - In: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY. - ISSN 1593-098X. - (2019). [Epub ahead of print]
Effects of glucocorticoids on B-cell subpopulations in patients with IgG4-related disease
Lanzillotta, Marco;Della-Torre, Emanuel;Arcidiacono, Paolo Giorgio;Partelli, Stefano;Falconi, Massimo;Ciceri, Fabio;Dagna, Lorenzo
2019-01-01
Abstract
Glucocorticoids induce prompt clinical improvement in patients with IgG4-related disease (IgG4-RD) but their mechanisms of action in this specific condition are not fully understood. B lymphocytes appear central to IgG4-RD pathogenesis because B-cell depletion with rituximab leads to swift clinical responses. In the present work we aim to assess the effects of glucocorticoids on B-cell subpopulations in patients with IgG4-RD.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
