MicroRNAs (miRNA) are tiny, noncoding, small, endogenous RNAs that play major roles in neoplastic transformation and could therefore offer a better quantitative and noninvasive method for the diagnosis and prognosis of colorectal cancer (CRC) using feces. In the present study, we screened feces for 648 miRNAs and analyzed the role of miR-144* as a potential CRC diagnostic marker.

Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer / Kalimutho, M; Del Vecchio Blanco, G; Di Cecilia, S; Sileri, P; Cretella, M; Pallone, F; Federici, G; Bernardini, S. - In: JOURNAL OF GASTROENTEROLOGY. - ISSN 0944-1174. - 46:12(2011), pp. 1391-1402. [10.1007/s00535-011-0456-0]

Differential expression of miR-144* as a novel fecal-based diagnostic marker for colorectal cancer

Sileri P;
2011-01-01

Abstract

MicroRNAs (miRNA) are tiny, noncoding, small, endogenous RNAs that play major roles in neoplastic transformation and could therefore offer a better quantitative and noninvasive method for the diagnosis and prognosis of colorectal cancer (CRC) using feces. In the present study, we screened feces for 648 miRNAs and analyzed the role of miR-144* as a potential CRC diagnostic marker.
2011
Sensitivity and Specificity; MicroRNAs; Humans; Temperature; Aged; Reverse Transcriptase Polymerase Chain Reaction; Gene Expression Regulation; Neoplastic; Aged; 80 and over; Adult; Middle Aged; Feces; Tumor Markers; Biological; Time Factors; Colorectal Neoplasms; Female; Male
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/96309
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