IRIS
6.1 Brevetto
 Distribuzione geografica
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Continente #
EU - Europa 3.484
AS - Asia 3.288
NA - Nord America 2.178
SA - Sud America 828
AF - Africa 67
OC - Oceania 1
Totale 9.846
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Nazione #
US - Stati Uniti d'America 2.069
RU - Federazione Russa 1.992
SG - Singapore 1.307
CN - Cina 1.036
BR - Brasile 670
SE - Svezia 629
HK - Hong Kong 387
VN - Vietnam 304
IT - Italia 233
FR - Francia 185
DE - Germania 158
FI - Finlandia 108
IN - India 79
GB - Regno Unito 57
AR - Argentina 56
CA - Canada 56
ZA - Sudafrica 34
EC - Ecuador 30
MX - Messico 30
BD - Bangladesh 28
CO - Colombia 26
PL - Polonia 26
ID - Indonesia 24
IQ - Iraq 23
NL - Olanda 21
ES - Italia 13
PY - Paraguay 13
TR - Turchia 12
UA - Ucraina 12
AT - Austria 11
CL - Cile 10
VE - Venezuela 10
IR - Iran 9
MA - Marocco 9
PK - Pakistan 9
RO - Romania 9
JP - Giappone 8
AE - Emirati Arabi Uniti 7
KE - Kenya 6
KZ - Kazakistan 6
SA - Arabia Saudita 6
TN - Tunisia 6
UY - Uruguay 6
JM - Giamaica 5
JO - Giordania 5
MY - Malesia 5
OM - Oman 5
AZ - Azerbaigian 4
CH - Svizzera 4
EG - Egitto 4
IE - Irlanda 4
IL - Israele 4
PA - Panama 4
PE - Perù 4
UZ - Uzbekistan 4
AL - Albania 3
BO - Bolivia 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
RS - Serbia 3
AM - Armenia 2
BH - Bahrain 2
BY - Bielorussia 2
DZ - Algeria 2
GT - Guatemala 2
LT - Lituania 2
MD - Moldavia 2
NP - Nepal 2
PH - Filippine 2
TW - Taiwan 2
BE - Belgio 1
BG - Bulgaria 1
BS - Bahamas 1
CG - Congo 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
HN - Honduras 1
HR - Croazia 1
KN - Saint Kitts e Nevis 1
LB - Libano 1
LC - Santa Lucia 1
MK - Macedonia 1
NZ - Nuova Zelanda 1
PR - Porto Rico 1
PT - Portogallo 1
QA - Qatar 1
SI - Slovenia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TL - Timor Orientale 1
TT - Trinidad e Tobago 1
VG - Isole Vergini Britanniche 1
Totale 9.846
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Città #
Dallas 548
Singapore 430
Moscow 395
Hong Kong 382
Ashburn 243
Shanghai 243
San Jose 211
Hefei 174
Beijing 152
Lauterbourg 148
Lawrence 136
Princeton 136
Ho Chi Minh City 107
Helsinki 83
New York 69
Hanoi 62
São Paulo 57
Los Angeles 51
Milan 51
Orem 51
Munich 34
Washington 29
Turku 24
Boardman 23
Bologna 23
Pune 23
Ancona 22
Warsaw 22
Guangzhou 20
Chennai 19
Johannesburg 19
Da Nang 18
Denver 18
Montreal 18
Nuremberg 18
Rio de Janeiro 18
Rome 18
Stockholm 16
Brasília 15
Brooklyn 15
Curitiba 15
Poplar 15
Toronto 14
Guarulhos 13
Haiphong 13
Atlanta 12
Baghdad 12
Guayaquil 12
Hải Dương 12
Mexico City 12
Amsterdam 10
Dhaka 10
Frankfurt am Main 10
London 10
Manchester 10
Perugia 10
Quito 10
Santa Clara 10
Shenzhen 10
Campinas 9
Chicago 9
Houston 9
Cape Town 8
New Delhi 8
Phoenix 8
Porto Alegre 8
Tokyo 8
Turin 8
Bogotá 7
Buenos Aires 7
Hangzhou 7
Nova Iguaçu 7
Tianjin 7
Falkenstein 6
Nairobi 6
Piracicaba 6
Salvador 6
San Francisco 6
Santo André 6
São Bernardo do Campo 6
Thái Bình 6
Thái Nguyên 6
Asunción 5
Boston 5
Charlotte 5
Fortaleza 5
Limeira 5
Manaus 5
Montevideo 5
Santiago de Cali 5
Tehran 5
Amman 4
Ankara 4
Baku 4
Belo Horizonte 4
Betim 4
Bloomington 4
Canoas 4
Caracas 4
Ciudad del Este 4
Totale 4.606
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Nome #
System for physical activity, and related method 237
[Severe aortic stenosis successfully treated with percutaneous aortic valve implantation] 153
Ablation catheter with flexible tip and methods of making the same 126
2) HERV-H per l'uso come marcatore molecolare del Disturbo dello Spettro Autistico e relativo metodo diagnostico in vitro, kit diagnostico e usi medici (2012).GAUDI S F 116
Permanent Epigenetic Gene Silencing 111
SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS 109
INCREASE OF MYELOID MICROVESICLES IN THE CEREBROSPINAL FLUID AS BIOMARKER OF MICROGLIA/MACROPHAGE ACTIVATION IN NEUROLOGICAL DISORDERS 105
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION 103
GENE SILENCING 101
Treatment and Prevention of Cancer with HMGB1 Antagonists 99
Sistema per svolgere attività fisica, e relativo procedimento 98
RECOMBINANT LENTIVIRAL VECTOR FOR STEM CELL-BASED GENE THERAPY OF SICKLE CELL DISORDER 96
HMGB1 inhibitors and antagonista for the inhibition of atherosclerosis pathogenesis and development 95
Dispositivo di cannulazione vascolare 95
ACETYLATED HMGB1 PROTEIN 94
Use of HMGB2 and HMGB3 proteins for medical applications 92
Adjuvant incorporation in immunoanotherapeutics 88
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells 86
VIRAL VECTOR COMBINING GENE THERAPY AND GENOME EDITING APPROACHES FOR GENE THERAPY OF GENETIC DISORDERS 86
HMGB1 protein inhibitors for the regulation of smooth muscle cells and endothelial cells proliferation 82
Novel biomarkers 79
VECTOR PRODUCTION 78
Methods and compositions for targeted integration 75
Agents regulating vascular permeability 73
PROCEDIMENTO E SISTEMA PER LA RILEVAZIONE DI RISPOSTE BINARIE TRAMITE ANALISI DEL DIAMETRO PUPILLARE DI UN SOGGETTO 71
Formulations to administer SUMO2/3 71
Bottone anastomotico frammentabile 67
Spinginodo 67
Inhibitors of hepatitis B virus 66
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 65
Structure and function of the salicyclic acid binding sites on human hmgb1 and methods of use thereof for the rational design of both salicyclic acid derivatives and other agents that alter animal and plant hmgbs activities 64
Method for the preparation of new oligoclonal antibodies 63
Tricuspid valve repair using tension 63
Use of IL-7 and IL-15 for the genetic modification of memory T lymphocytes 63
Vaccine nanotechnology 63
MEZZO PER VEDERE UNA VALVOLA CARDIACA IN FASE INTRAOPERATORIA 63
Anti-idiotype monoclonal antibody directed against anti-TNF antibodies 61
Human monoclonal recombinant antibody against NS3 HCV protein and methods therefor 60
Collagen Scaffold in nervous system regeneration 60
Hmgb1 variants and uses thereof 60
Cyclic inhibitors of hepatitis B virus 60
Delivery tool for implantation of spool assembly coupled to a helical anchor 60
Anti-idiotype monoclonal antibodies as mimotopes of the HIV gp120 antigen 59
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen 59
Tricyclic inhibitors of hepatitis B virus 59
Cytokine conjugates (IL-12 –peptide conjugates) 58
Suturatrice meccanica circolare 58
Cromogranina A per uso come reagente in un metodo diagnostico o prognostico 58
INFLUENZA VIRUS AND TYPE 1 DIABETES 58
DISPOSITIVO PER USO IN EMODINAMICA 58
Anti-urokinase monoclonal antibody, matrix bearing it, test method, biochemical test kits which use it. 57
Phage Display Technology 57
“Non-invasive ventilation mask and use thereof” 57
Methods for treating cardiac reperfusion injury 57
Magnetically Guided Catheter With Flexible Tip 57
Suturatrice meccanica circolare 56
Monoclonal antibodies as a medicament for the therapeutic and/or prophylactic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections 56
Monoclonal antibodies against the TNF type-I receptor, process for their production and use thereofAnticorpi monoclonali anti-recettore di tipo 1 del TNF alfa, procedimento per la loro produzione e loro uso 56
Receptor-antibody sandwich assay. 56
Method of treating cardiac arrhythmias 56
Control for a Remote Navigation System 56
System and methods for locating and ablating arrhythomogenic tissues 56
PROTESI ANULARE PER VALVOLA MITRALE 56
Method and apparatus for tricuspid valve repair using tension 55
Dispositivo per la chirurgia endoscopica transanale 55
Nicotine immunonanotherapeutics 55
Targeting of antigen presenting cells with immunonanotherapeutics 55
RETAINING MECHANISMS FOR PROSTHETIC VALVES 55
Real heart case simulator 55
SULFONAMIDES USEFUL IN THE PREVENTION OF DIABETES 54
Monoclonal antibodies having homosubtype cross-neutralization properties against influenza A viruses subtype H1 54
Immobilized oligopeptides 54
Suturatrice automatica per borsa di tabacco 54
Liver gene expression associated with the inhibition of HBV replication or transcription 54
Irrigated Catheter with Improved fluid flow 54
CARDIAC TISSUE CINCHING 54
FOSSA OVALIS PENETRATION USING PROBING ELEMENTS 54
FOSSA OVALIS PENETRATION APPARATUS 54
Human Monoclonal Antibody Fab Fragments directed against HCV E2 glycoprotein and endowed with neutralizing activity 53
Réparation de valve tricuspide à l'aide d'une tension 53
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 53
System and Network for Remote Medical Procedures 53
METHOD AND SYSTEM FOR DETECTING VOLUNTARY BINARY RESPONSES BY ANALYZING THE PUPIL DIAMETER OF A SUBJECT 53
SUMO and uses thereof 53
Dispositivo anastomotico ad anelli 52
Multi-Electrode Irrigated Balloon Catheter 52
PERCUTANEOUS TETHER LOCKING 52
Non linear peptides hydropathically complementary to know amino acid sequences, process for the production and used thereof 51
INHIBITORS OF CXCR1/2 AS ADJUVANTS IN THE TRANSPLANT OF PANCREATIC ISLETS 51
Dispositivo anastomotico ad anelli 51
Solid-phase receptor assay for antibiotics of the vancomycin class. 51
Dispositivo ad anelli frammentabili 51
Use of common gamma-chain cytokines for the visualization, isolation and genetic modification of memory T lymphocytes 51
STK4 inhibitors for treatment of hematological malignancies 51
IMPLANTATION OF REPAIR CHORDS IN THE HEART 51
Combination product (Use of IDO inhibitors in cancer therapy with targeted interferon gamma) 50
Strumento automatico per suture a borsa di tabacco 50
Novel Targets in Multiple Myeloma and Other Disorders 50
ADJUSTABLE REPAIR CHORDS AND SPOOL MECHANISM THEREFOR 50
Use of HMGB1 and analogues thereof for wound healing 49
Totale 6.771
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20211 0 0 0 0 0 0 0 0 0 0 1 0
2021/2022142 4 0 0 84 4 4 3 9 10 12 6 6
2022/2023933 299 260 109 3 1 113 8 36 58 11 15 20
2023/2024473 40 11 132 32 23 46 12 29 0 31 12 105
2024/20252.186 259 38 61 86 33 166 320 158 351 224 252 238
2025/20266.163 480 602 500 898 474 171 488 449 1.730 312 59 0
Totale 9.924