IRIS
6.1 Brevetto
 Distribuzione geografica
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Continente #
EU - Europa 3.509
AS - Asia 3.291
NA - Nord America 2.393
SA - Sud America 837
Continente sconosciuto - Info sul continente non disponibili 81
AF - Africa 67
OC - Oceania 1
Totale 10.179
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Nazione #
US - Stati Uniti d'America 2.260
RU - Federazione Russa 1.992
SG - Singapore 1.307
CN - Cina 1.037
BR - Brasile 674
SE - Svezia 629
HK - Hong Kong 388
VN - Vietnam 304
IT - Italia 249
FR - Francia 187
DE - Germania 160
FI - Finlandia 109
IN - India 79
CA - Canada 71
GB - Regno Unito 58
AR - Argentina 57
ZA - Sudafrica 34
EC - Ecuador 31
MX - Messico 30
CO - Colombia 29
BD - Bangladesh 28
PL - Polonia 27
ID - Indonesia 24
IQ - Iraq 23
NL - Olanda 21
ES - Italia 13
PY - Paraguay 13
TR - Turchia 12
UA - Ucraina 12
AT - Austria 11
CL - Cile 10
VE - Venezuela 10
IR - Iran 9
JP - Giappone 9
MA - Marocco 9
PK - Pakistan 9
RO - Romania 9
AE - Emirati Arabi Uniti 7
JM - Giamaica 6
KE - Kenya 6
KZ - Kazakistan 6
SA - Arabia Saudita 6
TN - Tunisia 6
UY - Uruguay 6
IE - Irlanda 5
JO - Giordania 5
MY - Malesia 5
OM - Oman 5
AZ - Azerbaigian 4
CH - Svizzera 4
EG - Egitto 4
IL - Israele 4
PA - Panama 4
PE - Perù 4
UZ - Uzbekistan 4
AL - Albania 3
BO - Bolivia 3
CR - Costa Rica 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
RS - Serbia 3
AM - Armenia 2
BH - Bahrain 2
BY - Bielorussia 2
DZ - Algeria 2
GT - Guatemala 2
HN - Honduras 2
LT - Lituania 2
MD - Moldavia 2
NP - Nepal 2
PH - Filippine 2
PR - Porto Rico 2
SV - El Salvador 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
BE - Belgio 1
BG - Bulgaria 1
BS - Bahamas 1
CG - Congo 1
CI - Costa d'Avorio 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
HR - Croazia 1
KN - Saint Kitts e Nevis 1
LB - Libano 1
LC - Santa Lucia 1
MK - Macedonia 1
NI - Nicaragua 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
QA - Qatar 1
SI - Slovenia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TL - Timor Orientale 1
VG - Isole Vergini Britanniche 1
Totale 10.098
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Città #
Dallas 550
Singapore 430
Moscow 395
Hong Kong 383
Ashburn 245
Shanghai 243
San Jose 212
Hefei 174
Beijing 152
Lauterbourg 148
Lawrence 136
Princeton 136
Ho Chi Minh City 107
Helsinki 83
New York 78
Hanoi 62
São Paulo 58
Los Angeles 55
Milan 54
Orem 51
Santa Clara 35
Munich 34
Washington 29
Turku 24
Boardman 23
Bologna 23
Pune 23
Warsaw 23
Ancona 22
Guangzhou 20
Chennai 19
Denver 19
Johannesburg 19
Rio de Janeiro 19
Da Nang 18
Montreal 18
Nuremberg 18
Rome 18
Brooklyn 16
Stockholm 16
Brasília 15
Curitiba 15
Poplar 15
Toronto 15
Atlanta 14
Guarulhos 13
Haiphong 13
Baghdad 12
Guayaquil 12
Houston 12
Hải Dương 12
London 12
Mexico City 12
Quito 11
Amsterdam 10
Campinas 10
Chicago 10
Dhaka 10
Frankfurt am Main 10
Manchester 10
Miami 10
Perugia 10
Phoenix 10
Shenzhen 10
Tokyo 9
Bogotá 8
Cape Town 8
New Delhi 8
Porto Alegre 8
Seattle 8
Turin 8
Boston 7
Buenos Aires 7
Hangzhou 7
Nova Iguaçu 7
Tianjin 7
Charlotte 6
Falkenstein 6
Nairobi 6
Naples 6
Piracicaba 6
Salvador 6
San Francisco 6
Santo André 6
São Bernardo do Campo 6
Thái Bình 6
Thái Nguyên 6
Asunción 5
Fortaleza 5
Limeira 5
Manaus 5
Montevideo 5
Ottawa 5
Santiago de Cali 5
Tehran 5
Amman 4
Ankara 4
Baku 4
Belo Horizonte 4
Betim 4
Totale 4.689
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Nome #
System for physical activity, and related method 237
[Severe aortic stenosis successfully treated with percutaneous aortic valve implantation] 156
Ablation catheter with flexible tip and methods of making the same 127
2) HERV-H per l'uso come marcatore molecolare del Disturbo dello Spettro Autistico e relativo metodo diagnostico in vitro, kit diagnostico e usi medici (2012).GAUDI S F 116
Permanent Epigenetic Gene Silencing 114
SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS 110
INCREASE OF MYELOID MICROVESICLES IN THE CEREBROSPINAL FLUID AS BIOMARKER OF MICROGLIA/MACROPHAGE ACTIVATION IN NEUROLOGICAL DISORDERS 105
GENE SILENCING 104
RECOMBINANT LENTIVIRAL VECTOR FOR STEM CELL-BASED GENE THERAPY OF SICKLE CELL DISORDER 103
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION 103
Treatment and Prevention of Cancer with HMGB1 Antagonists 100
Sistema per svolgere attività fisica, e relativo procedimento 99
ACETYLATED HMGB1 PROTEIN 99
Use of HMGB2 and HMGB3 proteins for medical applications 96
HMGB1 inhibitors and antagonista for the inhibition of atherosclerosis pathogenesis and development 95
Dispositivo di cannulazione vascolare 95
Adjuvant incorporation in immunoanotherapeutics 89
VIRAL VECTOR COMBINING GENE THERAPY AND GENOME EDITING APPROACHES FOR GENE THERAPY OF GENETIC DISORDERS 88
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells 86
Novel biomarkers 82
HMGB1 protein inhibitors for the regulation of smooth muscle cells and endothelial cells proliferation 82
VECTOR PRODUCTION 78
PROCEDIMENTO E SISTEMA PER LA RILEVAZIONE DI RISPOSTE BINARIE TRAMITE ANALISI DEL DIAMETRO PUPILLARE DI UN SOGGETTO 77
Methods and compositions for targeted integration 75
Agents regulating vascular permeability 74
Formulations to administer SUMO2/3 72
Bottone anastomotico frammentabile 68
Spinginodo 68
Inhibitors of hepatitis B virus 67
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 66
Structure and function of the salicyclic acid binding sites on human hmgb1 and methods of use thereof for the rational design of both salicyclic acid derivatives and other agents that alter animal and plant hmgbs activities 66
MEZZO PER VEDERE UNA VALVOLA CARDIACA IN FASE INTRAOPERATORIA 65
Method for the preparation of new oligoclonal antibodies 64
Tricuspid valve repair using tension 64
Anti-idiotype monoclonal antibodies as mimotopes of the HIV gp120 antigen 63
Use of IL-7 and IL-15 for the genetic modification of memory T lymphocytes 63
Vaccine nanotechnology 63
Anti-idiotype monoclonal antibody directed against anti-TNF antibodies 62
Hmgb1 variants and uses thereof 62
Delivery tool for implantation of spool assembly coupled to a helical anchor 62
Collagen Scaffold in nervous system regeneration 61
Monoclonal antibodies against the TNF type-I receptor, process for their production and use thereofAnticorpi monoclonali anti-recettore di tipo 1 del TNF alfa, procedimento per la loro produzione e loro uso 61
Dispositivo per la chirurgia endoscopica transanale 61
Tricyclic inhibitors of hepatitis B virus 61
Human monoclonal recombinant antibody against NS3 HCV protein and methods therefor 60
Cytokine conjugates (IL-12 –peptide conjugates) 60
Suturatrice meccanica circolare 60
Monoclonal antibodies having homosubtype cross-neutralization properties against influenza A viruses subtype H1 60
Cyclic inhibitors of hepatitis B virus 60
Anti-urokinase monoclonal antibody, matrix bearing it, test method, biochemical test kits which use it. 59
Phage Display Technology 59
Cromogranina A per uso come reagente in un metodo diagnostico o prognostico 59
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen 59
Monoclonal antibodies as a medicament for the therapeutic and/or prophylactic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections 58
“Non-invasive ventilation mask and use thereof” 58
Magnetically Guided Catheter With Flexible Tip 58
INFLUENZA VIRUS AND TYPE 1 DIABETES 58
DISPOSITIVO PER USO IN EMODINAMICA 58
Selective immunoassay for the detection of pro-urokinase and urokinase 57
Fusion of cytokines and targeting peptides 57
Receptor-antibody sandwich assay. 57
Method and apparatus for tricuspid valve repair using tension 57
Methods for treating cardiac reperfusion injury 57
Control for a Remote Navigation System 57
PROTESI ANULARE PER VALVOLA MITRALE 57
Suturatrice meccanica circolare 56
Suturatrice automatica per borsa di tabacco 56
Method of treating cardiac arrhythmias 56
System and methods for locating and ablating arrhythomogenic tissues 56
Nicotine immunonanotherapeutics 56
Targeting of antigen presenting cells with immunonanotherapeutics 56
RETAINING MECHANISMS FOR PROSTHETIC VALVES 56
Immobilized oligopeptides 55
Liver gene expression associated with the inhibition of HBV replication or transcription 55
Irrigated Catheter with Improved fluid flow 55
CARDIAC TISSUE CINCHING 55
FOSSA OVALIS PENETRATION USING PROBING ELEMENTS 55
FOSSA OVALIS PENETRATION APPARATUS 55
Real heart case simulator 55
SULFONAMIDES USEFUL IN THE PREVENTION OF DIABETES 54
Dispositivo anastomotico ad anelli 54
Human Monoclonal Antibody Fab Fragments directed against HCV E2 glycoprotein and endowed with neutralizing activity 53
Réparation de valve tricuspide à l'aide d'une tension 53
Strumento automatico per suture a borsa di tabacco 53
Dispositivo ad anelli frammentabili 53
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 53
System and Network for Remote Medical Procedures 53
Multi-Electrode Irrigated Balloon Catheter 53
METHOD AND SYSTEM FOR DETECTING VOLUNTARY BINARY RESPONSES BY ANALYZING THE PUPIL DIAMETER OF A SUBJECT 53
SUMO and uses thereof 53
PERCUTANEOUS TETHER LOCKING 53
IMPLANTATION OF REPAIR CHORDS IN THE HEART 53
Non linear peptides hydropathically complementary to know amino acid sequences, process for the production and used thereof 52
INHIBITORS OF CXCR1/2 AS ADJUVANTS IN THE TRANSPLANT OF PANCREATIC ISLETS 52
Dispositivo anastomotico ad anelli 52
Combination product (Use of IDO inhibitors in cancer therapy with targeted interferon gamma) 51
Strumento automatico per suture a borsa di tabacco 51
Solid-phase receptor assay for antibiotics of the vancomycin class. 51
Modified cytokines for therapeutic use 51
Use of common gamma-chain cytokines for the visualization, isolation and genetic modification of memory T lymphocytes 51
Totale 6.913
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022138 0 0 0 84 4 4 3 9 10 12 6 6
2022/2023933 299 260 109 3 1 113 8 36 58 11 15 20
2023/2024473 40 11 132 32 23 46 12 29 0 31 12 105
2024/20252.186 259 38 61 86 33 166 320 158 351 224 252 238
2025/20266.214 480 602 500 898 474 171 488 449 1.730 312 70 40
2026/2027204 202 2 0 0 0 0 0 0 0 0 0 0
Totale 10.179