IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
AS - Asia 6.173
NA - Nord America 3.198
EU - Europa 2.665
SA - Sud America 2.101
AF - Africa 132
OC - Oceania 22
Continente sconosciuto - Info sul continente non disponibili 2
Totale 14.293
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Nazione #
US - Stati Uniti d'America 3.074
SG - Singapore 2.755
BR - Brasile 1.748
CN - Cina 1.571
SE - Svezia 1.177
HK - Hong Kong 803
VN - Vietnam 548
IT - Italia 406
RU - Federazione Russa 340
DE - Germania 203
AR - Argentina 137
FI - Finlandia 119
IN - India 118
GB - Regno Unito 93
EC - Ecuador 81
IE - Irlanda 68
BD - Bangladesh 66
AT - Austria 60
JP - Giappone 56
CA - Canada 53
ID - Indonesia 53
ZA - Sudafrica 48
MX - Messico 43
NL - Olanda 38
FR - Francia 36
IQ - Iraq 36
PL - Polonia 36
PY - Paraguay 32
TR - Turchia 28
CO - Colombia 27
MA - Marocco 24
CL - Cile 22
ES - Italia 21
PK - Pakistan 21
AU - Australia 20
PE - Perù 19
DZ - Algeria 17
VE - Venezuela 17
UA - Ucraina 16
CH - Svizzera 14
UY - Uruguay 14
EG - Egitto 13
SA - Arabia Saudita 12
UZ - Uzbekistan 11
TN - Tunisia 10
AE - Emirati Arabi Uniti 9
IR - Iran 9
KR - Corea 9
IL - Israele 8
KZ - Kazakistan 8
AZ - Azerbaigian 7
KE - Kenya 6
LT - Lituania 6
HN - Honduras 5
KG - Kirghizistan 5
KW - Kuwait 5
PA - Panama 5
AL - Albania 4
AM - Armenia 4
GR - Grecia 4
JM - Giamaica 4
JO - Giordania 4
MK - Macedonia 4
MY - Malesia 4
NG - Nigeria 4
NP - Nepal 4
BB - Barbados 3
BO - Bolivia 3
DM - Dominica 3
DO - Repubblica Dominicana 3
HU - Ungheria 3
NO - Norvegia 3
PS - Palestinian Territory 3
SC - Seychelles 3
TW - Taiwan 3
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
BH - Bahrain 2
CI - Costa d'Avorio 2
CY - Cipro 2
DK - Danimarca 2
GE - Georgia 2
ML - Mali 2
NZ - Nuova Zelanda 2
PH - Filippine 2
SK - Slovacchia (Repubblica Slovacca) 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
XK - ???statistics.table.value.countryCode.XK??? 2
BW - Botswana 1
BY - Bielorussia 1
EE - Estonia 1
ET - Etiopia 1
GD - Grenada 1
GT - Guatemala 1
KH - Cambogia 1
LB - Libano 1
LU - Lussemburgo 1
LV - Lettonia 1
OM - Oman 1
Totale 14.288
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Città #
Singapore 952
Hong Kong 793
Dallas 540
Shanghai 434
Ashburn 395
Hefei 375
Lawrence 370
Princeton 370
Ho Chi Minh City 203
Beijing 169
New York 164
São Paulo 153
Moscow 111
Milan 109
Hanoi 108
Helsinki 97
Los Angeles 75
Rio de Janeiro 68
Dublin 64
Nuremberg 56
Tokyo 40
Boardman 38
Pune 35
Belo Horizonte 32
Quito 30
Vienna 30
Curitiba 29
Warsaw 29
Brasília 27
Porto Alegre 27
Guayaquil 26
Brooklyn 25
Washington 24
Guangzhou 23
Munich 23
Seattle 23
Da Nang 22
Johannesburg 21
Haiphong 20
Orem 20
Phoenix 20
Thái Bình 20
Montreal 19
Poplar 19
Turku 19
Campinas 18
Denver 18
Biên Hòa 17
London 17
San Jose 17
Goiânia 16
Guarulhos 16
Salvador 16
Santo André 16
Stockholm 16
Boston 15
Santa Clara 14
Tianjin 14
Chennai 13
Council Bluffs 13
Fortaleza 13
Hangzhou 13
Lima 13
Ankara 12
Atlanta 12
Cape Town 12
Dhaka 12
Houston 12
Manaus 12
Montes Claros 12
Montevideo 12
São José 12
The Dalles 12
Toronto 12
Borås 11
Monza 11
Naples 11
Sydney 11
São José dos Campos 11
Can Tho 10
Chicago 10
Hải Dương 10
Itajaí 10
Manchester 10
Ninh Bình 10
Pelotas 10
Reston 10
Ribeirão Preto 10
Rome 10
Turin 10
Belém 9
Buenos Aires 9
Caxias do Sul 9
Frankfurt am Main 9
Hanover 9
Mexico City 9
Mumbai 9
Shenzhen 9
Shijiazhuang 9
Sorocaba 9
Totale 6.909
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 327
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 192
Loss of mismatched HLA in leukemia after stem-cell transplantation 135
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 132
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 124
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 115
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 106
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 94
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 90
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 90
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 88
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 86
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 85
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 82
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 82
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 81
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 79
A dual role for genetically modified lymphocytes in cancer immunotherapy 77
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 76
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 76
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 75
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 71
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 70
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 68
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 67
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 67
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 66
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 66
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 66
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 64
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 64
A family of rapidly evolving genes from the sex reversal critical region in Xp21 63
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 63
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 63
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 61
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 59
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 59
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 59
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency 59
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 58
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 57
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 57
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 56
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 56
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 55
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 55
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 55
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 54
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 53
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 52
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 51
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 51
Coronaviridae and SARS-associated coronavirus strain HSR1 51
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 50
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 50
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 50
Terapia genica e malattia ereditaria 50
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 50
SUICIDE GENE TRANSFER INTO DONOR LYMPHOCYTES ALLOWS EARLY AND EFFECTIVE IMMUNE-RECONSTITUTION AFTER FAMILY HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LEUKEMIAS: RESULTS OF THE TK007 STUDY 50
The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity 49
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 49
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 48
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 47
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 47
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 47
CD44v6 is associated with chemoresistance induced by bone marrow-derived mesenchymal stromal cells 47
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 47
Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites. 47
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival 46
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 45
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 45
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 45
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 45
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 45
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 44
Improving the safety of cell therapy with the TK-suicide gene. 44
A new chance for SCID gene therapy 43
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 43
Editing human lymphocyte specificity for safe and effective adoptive immunotherapy of leukemia 43
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 42
Retroviral vector gene-transfer into donor peripheral-blood lymphocytes for in-vitro selection and in-vivo immunomodulation of donor antitumor immunity after allo-BMT 42
Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT 42
Gene-transfer into peripheral-blood lymphocytes for in-vivo immunomodulation of donor antitumor immunity in a patient affected by EBV-induced lymphoma 42
Loss of Mismatched HLA as a Mechanism of Leukemia Immune Escape in Family Haploidentical and Unrelated HSCT: Analysis of 103 Transplants From Alternative Donors 42
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 41
Naive-Derived Memory Stem T Cells: A Novel Promising Platform for Cancer Immune-Gene Therapy 41
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor promoting neutrophils. 41
Editing human lymphocytes specificity for safe and effective adoptive immunoterapy of leukemia 41
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 41
Inhibition of natural killer activity by human bronchoalveolar macrophages. 40
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 40
Dual Transgenesis of T Cells with a CD44v6 CAR and a Suicide Gene for the Safe Eradication of Myeloid Leukemia and Myeloma 40
Kinetics of acute and chronic GvHD control by ganciclovir in-vivo HSV-TK suicide gene activation: long-term GvHD-free survival in 57 patients after haploidentical TK-cells 40
Gene Therapy 39
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement 39
STRUCTURAL BASIS FOR THE INTERATION OF ISODGR WITH RGD-BINDING SITE OF αvβ3 INTEGRIN 39
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours 39
Long-term safety and correction of immune and metabolic defects in ADA-SCID children treated with gene therapy 39
Suicide gene transduced T-cells for the regulation of the graft-versus-leukemia effect 39
In vivo and in vitro models for analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency 39
Totale 6.272
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Categoria #
all - tutte 133.876
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 133.876
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20214 0 0 0 0 0 0 1 0 3 0 0 0
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.133 854 480 134 14 19 263 75 127 98 25 26 18
2023/2024997 66 60 98 158 60 195 54 65 6 52 44 139
2024/20254.505 593 67 49 137 111 345 553 350 909 639 372 380
2025/20266.432 984 1.184 1.081 2.186 790 207 0 0 0 0 0 0
Totale 14.422