IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
AS - Asia 7.619
EU - Europa 6.958
NA - Nord America 5.343
SA - Sud America 2.197
AF - Africa 156
Continente sconosciuto - Info sul continente non disponibili 132
OC - Oceania 26
Totale 22.431
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Nazione #
US - Stati Uniti d'America 5.102
RU - Federazione Russa 3.955
SG - Singapore 2.888
CN - Cina 2.452
BR - Brasile 1.806
SE - Svezia 1.179
HK - Hong Kong 881
VN - Vietnam 704
IT - Italia 559
FR - Francia 373
DE - Germania 230
GB - Regno Unito 173
IN - India 152
AR - Argentina 147
BD - Bangladesh 146
FI - Finlandia 121
CA - Canada 99
EC - Ecuador 91
IE - Irlanda 70
MX - Messico 66
AT - Austria 62
JP - Giappone 61
ID - Indonesia 60
NL - Olanda 55
ZA - Sudafrica 54
IQ - Iraq 50
PL - Polonia 39
TR - Turchia 37
CO - Colombia 34
PY - Paraguay 34
ES - Italia 33
MA - Marocco 26
AU - Australia 24
CL - Cile 23
PK - Pakistan 22
VE - Venezuela 21
DZ - Algeria 19
PE - Perù 19
UA - Ucraina 19
UY - Uruguay 16
CH - Svizzera 15
SA - Arabia Saudita 15
UZ - Uzbekistan 15
EG - Egitto 14
JM - Giamaica 14
TN - Tunisia 14
CR - Costa Rica 12
MY - Malesia 12
AE - Emirati Arabi Uniti 11
KR - Corea 10
NP - Nepal 10
AZ - Azerbaigian 9
IR - Iran 9
JO - Giordania 9
AL - Albania 8
IL - Israele 8
KZ - Kazakistan 8
CZ - Repubblica Ceca 7
HN - Honduras 7
LT - Lituania 7
PH - Filippine 7
GR - Grecia 6
HU - Ungheria 6
KE - Kenya 6
PA - Panama 6
BE - Belgio 5
KG - Kirghizistan 5
KW - Kuwait 5
MD - Moldavia 5
NG - Nigeria 5
NI - Nicaragua 5
PR - Porto Rico 5
SV - El Salvador 5
AM - Armenia 4
BB - Barbados 4
BH - Bahrain 4
BO - Bolivia 4
CY - Cipro 4
KH - Cambogia 4
MK - Macedonia 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
TT - Trinidad e Tobago 4
TW - Taiwan 4
BY - Bielorussia 3
DM - Dominica 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
GT - Guatemala 3
NO - Norvegia 3
RO - Romania 3
SC - Seychelles 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
DK - Danimarca 2
GE - Georgia 2
HR - Croazia 2
LC - Santa Lucia 2
Totale 22.272
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Città #
Singapore 1.018
Moscow 925
Hong Kong 864
San Jose 666
Ashburn 624
Dallas 552
Shanghai 455
Council Bluffs 383
Hefei 376
Lawrence 370
Princeton 370
Lauterbourg 325
Ho Chi Minh City 259
New York 218
Beijing 212
São Paulo 159
Hanoi 146
Milan 125
Santa Clara 114
Helsinki 98
Los Angeles 92
Rio de Janeiro 72
Dublin 66
Nuremberg 58
London 45
Tokyo 43
Orem 41
Boardman 40
Phoenix 37
Quito 37
Brooklyn 36
Pune 35
Rome 34
Belo Horizonte 33
Guangzhou 33
Vienna 32
Warsaw 32
Boston 30
Curitiba 30
Da Nang 30
Haiphong 29
Guayaquil 28
Porto Alegre 28
Brasília 27
Seattle 27
Washington 26
Chicago 25
Johannesburg 25
Montreal 24
Munich 23
Manchester 22
Atlanta 20
Denver 20
Frankfurt am Main 20
Naples 20
Poplar 20
Thái Bình 20
Biên Hòa 19
Chennai 19
Toronto 19
Turku 19
Campinas 18
Houston 18
Las Vegas 18
Mexico City 18
Stockholm 18
Tianjin 18
Goiânia 17
Guarulhos 17
Salvador 17
Santo André 16
Shenzhen 16
Hangzhou 15
Fortaleza 14
Hải Dương 14
Montevideo 14
Mumbai 14
Turin 14
Baghdad 13
Dhaka 13
Lima 13
The Dalles 13
Ankara 12
Buffalo 12
Can Tho 12
Cape Town 12
Manaus 12
Montes Claros 12
Monza 12
Philadelphia 12
San Francisco 12
São José 12
Tashkent 12
Borås 11
Buenos Aires 11
Cambridge 11
Itajaí 11
Ninh Bình 11
Pelotas 11
Reston 11
Totale 10.132
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 430
Loss of mismatched HLA in leukemia after stem-cell transplantation 217
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 213
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 185
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 178
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 172
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 147
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 140
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 140
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 129
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 128
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 123
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 123
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 121
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 120
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 117
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 116
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 116
A dual role for genetically modified lymphocytes in cancer immunotherapy 115
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 113
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 112
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 112
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 109
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 106
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 105
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 105
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 105
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 104
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 103
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 102
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 101
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 101
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 100
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 98
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 96
A family of rapidly evolving genes from the sex reversal critical region in Xp21 95
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 95
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 93
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 92
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 92
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 91
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 91
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 87
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 86
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency 86
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 85
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 85
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 84
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 83
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 82
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 80
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 79
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 78
The IL-1/IL-1 receptor axis and tumor cell released inflammasome adaptor ASC are key regulators of TSLP secretion by cancer associated fibroblasts in pancreatic cancer 77
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival 76
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours 76
Coronaviridae and SARS-associated coronavirus strain HSR1 76
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors 76
A new chance for SCID gene therapy 75
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 75
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 75
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 74
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 74
SUICIDE GENE TRANSFER INTO DONOR LYMPHOCYTES ALLOWS EARLY AND EFFECTIVE IMMUNE-RECONSTITUTION AFTER FAMILY HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LEUKEMIAS: RESULTS OF THE TK007 STUDY 74
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 73
Changes in T-cell responses against human herpes virus-8 correlate with the disease course of latrogenic kaposi’s sarcoma in a patient with undifferentiated arthritis 72
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 72
Terapia genica e malattia ereditaria 72
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 71
The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity 71
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 70
Inhibition of natural killer activity by human bronchoalveolar macrophages. 69
Dual Transgenesis of T Cells with a CD44v6 CAR and a Suicide Gene for the Safe Eradication of Myeloid Leukemia and Myeloma 69
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 68
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 68
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 68
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 67
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 67
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors 66
Safety of retroviral gene marking with a truncated NGF receptor 66
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 66
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 65
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 65
Retroviral vector gene-transfer into donor peripheral-blood lymphocytes for in-vitro selection and in-vivo immunomodulation of donor antitumor immunity after allo-BMT 65
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 65
Targeting chemoresistant myeloid leukaemia and multiple myeloma through genetic redirection of T cells against CD44 variant 6. Presented at the 19th Annual Meeting of the European Society of Gene and Cellular Therapy 64
Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA- Immunodeficient Patients 64
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells 64
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 64
STRUCTURAL BASIS FOR THE INTERATION OF ISODGR WITH RGD-BINDING SITE OF αvβ3 INTEGRIN 63
Improving the safety of cell therapy with the TK-suicide gene. 63
Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation 63
Editing human lymphocyte specificity for safe and effective adoptive immunotherapy of leukemia 63
Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT 63
Gene-transfer into peripheral-blood lymphocytes for in-vivo immunomodulation of donor antitumor immunity in a patient affected by EBV-induced lymphoma 63
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 62
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 62
T-cell depleted bone marrow transplants for leukemia: mechanisms of graft rejection and resistance to leukemic relapse 62
Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites. 62
Totale 9.494
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Categoria #
all - tutte 163.830
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 163.830
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.133 854 480 134 14 19 263 75 127 98 25 26 18
2023/2024997 66 60 98 158 60 195 54 65 6 52 44 139
2024/20254.505 593 67 49 137 111 345 553 350 909 639 372 380
2025/202613.556 984 1.184 1.081 2.186 790 386 1.189 900 3.578 713 329 236
2026/2027885 282 603 0 0 0 0 0 0 0 0 0 0
Totale 22.431