IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
AS - Asia 7.367
EU - Europa 6.812
NA - Nord America 4.099
SA - Sud America 2.181
AF - Africa 152
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 3
Totale 20.639
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Nazione #
RU - Federazione Russa 3.952
US - Stati Uniti d'America 3.938
SG - Singapore 2.837
CN - Cina 2.355
BR - Brasile 1.797
SE - Svezia 1.179
HK - Hong Kong 870
VN - Vietnam 696
IT - Italia 471
FR - Francia 372
DE - Germania 226
IN - India 149
AR - Argentina 146
GB - Regno Unito 140
FI - Finlandia 121
EC - Ecuador 87
BD - Bangladesh 84
IE - Irlanda 70
CA - Canada 64
AT - Austria 62
JP - Giappone 60
ID - Indonesia 57
MX - Messico 57
NL - Olanda 52
ZA - Sudafrica 52
IQ - Iraq 48
PL - Polonia 39
TR - Turchia 35
PY - Paraguay 34
CO - Colombia 32
ES - Italia 30
MA - Marocco 26
AU - Australia 23
CL - Cile 23
PK - Pakistan 22
VE - Venezuela 21
DZ - Algeria 19
PE - Perù 19
UA - Ucraina 19
UY - Uruguay 16
SA - Arabia Saudita 15
UZ - Uzbekistan 15
CH - Svizzera 14
EG - Egitto 14
TN - Tunisia 14
AE - Emirati Arabi Uniti 9
AZ - Azerbaigian 9
IR - Iran 9
JO - Giordania 9
KR - Corea 9
MY - Malesia 9
IL - Israele 8
KZ - Kazakistan 8
AL - Albania 7
LT - Lituania 7
NP - Nepal 7
PH - Filippine 7
HU - Ungheria 6
JM - Giamaica 6
KE - Kenya 6
PA - Panama 6
BE - Belgio 5
CR - Costa Rica 5
CZ - Repubblica Ceca 5
GR - Grecia 5
HN - Honduras 5
KG - Kirghizistan 5
KW - Kuwait 5
NG - Nigeria 5
AM - Armenia 4
BH - Bahrain 4
BO - Bolivia 4
CY - Cipro 4
MK - Macedonia 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
BB - Barbados 3
BY - Bielorussia 3
DM - Dominica 3
DO - Repubblica Dominicana 3
KH - Cambogia 3
NO - Norvegia 3
PR - Porto Rico 3
SC - Seychelles 3
TW - Taiwan 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
DK - Danimarca 2
ET - Etiopia 2
GE - Georgia 2
HR - Croazia 2
ML - Mali 2
NZ - Nuova Zelanda 2
RO - Romania 2
SN - Senegal 2
SR - Suriname 2
SV - El Salvador 2
SY - Repubblica araba siriana 2
Totale 20.620
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Città #
Singapore 1.001
Moscow 924
Hong Kong 854
Ashburn 571
Dallas 542
San Jose 519
Shanghai 451
Hefei 376
Lawrence 370
Princeton 370
Lauterbourg 325
Ho Chi Minh City 256
Beijing 193
New York 184
São Paulo 157
Hanoi 143
Milan 116
Helsinki 98
Los Angeles 79
Rio de Janeiro 71
Dublin 66
Nuremberg 58
Tokyo 43
Santa Clara 40
Boardman 39
Orem 36
Pune 35
Quito 34
Belo Horizonte 33
Vienna 32
Warsaw 32
Guangzhou 31
Curitiba 30
Da Nang 30
Haiphong 29
Porto Alegre 28
Brasília 27
Guayaquil 27
Brooklyn 26
Johannesburg 25
Washington 24
Munich 23
Seattle 23
Phoenix 22
London 21
Rome 21
Montreal 20
Poplar 20
Thái Bình 20
Biên Hòa 19
Chennai 19
Denver 19
Turku 19
Campinas 18
Frankfurt am Main 18
Stockholm 18
Boston 17
Guarulhos 17
Manchester 17
Salvador 17
Tianjin 17
Goiânia 16
Santo André 16
Shenzhen 16
Atlanta 15
Chicago 15
Council Bluffs 15
Hangzhou 14
Houston 14
Hải Dương 14
Montevideo 14
Toronto 14
Baghdad 13
Dhaka 13
Fortaleza 13
Lima 13
Mumbai 13
The Dalles 13
Ankara 12
Can Tho 12
Cape Town 12
Manaus 12
Mexico City 12
Montes Claros 12
Naples 12
São José 12
Tashkent 12
Turin 12
Borås 11
Buenos Aires 11
Itajaí 11
Monza 11
Ninh Bình 11
Pelotas 11
Reston 11
Ribeirão Preto 11
Sydney 11
São José dos Campos 11
Belém 9
Cambridge 9
Totale 9.199
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 372
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 212
Loss of mismatched HLA in leukemia after stem-cell transplantation 182
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 161
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 161
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 146
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 134
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 133
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 120
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 119
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 117
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 117
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 116
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 113
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 112
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 112
A dual role for genetically modified lymphocytes in cancer immunotherapy 110
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 109
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 104
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 102
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 102
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 101
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 100
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 98
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 97
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 96
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 95
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 95
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 94
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 93
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 92
A family of rapidly evolving genes from the sex reversal critical region in Xp21 91
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 91
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 90
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 89
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 88
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 86
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 85
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 85
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency 84
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 83
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 82
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 82
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 80
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 79
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 79
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 77
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival 75
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 74
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 74
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 73
A new chance for SCID gene therapy 72
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 72
Coronaviridae and SARS-associated coronavirus strain HSR1 72
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 71
SUICIDE GENE TRANSFER INTO DONOR LYMPHOCYTES ALLOWS EARLY AND EFFECTIVE IMMUNE-RECONSTITUTION AFTER FAMILY HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LEUKEMIAS: RESULTS OF THE TK007 STUDY 71
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 70
The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity 69
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 69
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 69
Terapia genica e malattia ereditaria 68
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 67
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 67
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 67
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 67
Inhibition of natural killer activity by human bronchoalveolar macrophages. 66
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 66
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors 65
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 64
Safety of retroviral gene marking with a truncated NGF receptor 64
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 64
Dual Transgenesis of T Cells with a CD44v6 CAR and a Suicide Gene for the Safe Eradication of Myeloid Leukemia and Myeloma 64
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 62
Gene-transfer into peripheral-blood lymphocytes for in-vivo immunomodulation of donor antitumor immunity in a patient affected by EBV-induced lymphoma 62
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 61
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 61
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 61
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 61
Retroviral vector gene-transfer into donor peripheral-blood lymphocytes for in-vitro selection and in-vivo immunomodulation of donor antitumor immunity after allo-BMT 61
Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT 61
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 61
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors 60
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 60
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 60
Editing human lymphocyte specificity for safe and effective adoptive immunotherapy of leukemia 60
CD44v6 is associated with chemoresistance induced by bone marrow-derived mesenchymal stromal cells 60
Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites. 60
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 60
Improving the safety of cell therapy with the TK-suicide gene. 59
Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA- Immunodeficient Patients 59
Editing human lymphocytes specificity for safe and effective adoptive immunoterapy of leukemia 59
Loss of Mismatched HLA as a Mechanism of Leukemia Immune Escape in Family Haploidentical and Unrelated HSCT: Analysis of 103 Transplants From Alternative Donors 59
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 59
Gene Therapy 58
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor promoting neutrophils. 58
Transfer of the ADA gene into human ADA-deficient T Lymphocytes reconstitutes specific immune functions 58
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 58
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells 57
Totale 8.697
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Categoria #
all - tutte 146.642
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 146.642
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.133 854 480 134 14 19 263 75 127 98 25 26 18
2023/2024997 66 60 98 158 60 195 54 65 6 52 44 139
2024/20254.505 593 67 49 137 111 345 553 350 909 639 372 380
2025/202612.778 984 1.184 1.081 2.186 790 386 1.189 900 3.578 500 0 0
Totale 20.768