IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
EU - Europa 2.007
NA - Nord America 1.500
AS - Asia 1.115
SA - Sud America 26
OC - Oceania 17
AF - Africa 12
Totale 4.677
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Nazione #
US - Stati Uniti d'America 1.488
SE - Svezia 1.158
CN - Cina 589
SG - Singapore 395
RU - Federazione Russa 303
IT - Italia 241
FI - Finlandia 99
IE - Irlanda 66
IN - India 62
DE - Germania 57
GB - Regno Unito 29
JP - Giappone 20
BR - Brasile 19
AU - Australia 15
FR - Francia 12
NL - Olanda 12
CA - Canada 11
HK - Hong Kong 8
IR - Iran 8
CH - Svizzera 7
DZ - Algeria 7
KR - Corea 7
IL - Israele 6
AT - Austria 4
ES - Italia 4
PL - Polonia 4
AR - Argentina 3
IQ - Iraq 3
NO - Norvegia 3
PE - Perù 3
SA - Arabia Saudita 3
BG - Bulgaria 2
DK - Danimarca 2
EG - Egitto 2
ID - Indonesia 2
KG - Kirghizistan 2
MA - Marocco 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
TR - Turchia 2
TW - Taiwan 2
EC - Ecuador 1
EE - Estonia 1
LU - Lussemburgo 1
MY - Malesia 1
NG - Nigeria 1
PA - Panama 1
PH - Filippine 1
PK - Pakistan 1
PT - Portogallo 1
UA - Ucraina 1
VN - Vietnam 1
Totale 4.677
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Città #
Shanghai 421
Lawrence 370
Princeton 370
Singapore 257
Ashburn 169
New York 106
Moscow 105
Helsinki 96
Milan 86
Dublin 64
Pune 35
Boardman 32
Washington 22
Los Angeles 21
Seattle 17
Guangzhou 15
Beijing 13
Borås 11
Dallas 11
London 10
Hanover 9
Monza 9
Rome 7
Sydney 7
Cambridge 6
Hyderabad 6
Mountain View 6
Shijiazhuang 6
São Paulo 6
Wuxi 6
Brisbane 5
Falls Church 5
Florence 5
Genoa 5
Naples 5
Overland Park 5
Perugia 5
Philadelphia 5
Redwood City 5
San Jose 5
Santa Marinella 5
Shenzhen 5
Turin 5
Verona 5
Bengaluru 4
Chevy Chase 4
Chicago 4
Delhi 4
Hamburg 4
Jiaxing 4
Moreno Valley 4
Quanzhou 4
Salerno 4
Tokyo 4
Vauderens 4
Xi'an 4
Aci Sant'Antonio 3
Algiers 3
Andover 3
Beaverton 3
Boston 3
Central 3
Chiyoda-ku 3
Florianópolis 3
Gijang-gun 3
Harbor Springs 3
Iowa City 3
Lappeenranta 3
Lima 3
Loughton 3
Melbourne 3
Moorestown 3
Oberndorf bei Salzburg 3
Paris 3
Park City 3
Phoenix 3
Pomona 3
Santa Clara 3
Santo André 3
St Petersburg 3
Toronto 3
Warsaw 3
Winnipeg 3
Zanjan 3
Zhengzhou 3
Zurich 3
Albuquerque 2
Ankara 2
Athlone 2
Aurich 2
Aurora 2
Belluno 2
Berlin 2
Bethesda 2
Birmingham 2
Bishkek 2
Bordeaux 2
Brooklyn 2
Buenos Aires 2
Bussero 2
Totale 2.535
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 230
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 80
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 63
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 60
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 51
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 48
Loss of mismatched HLA in leukemia after stem-cell transplantation 41
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 41
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 40
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 35
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 27
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 27
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 26
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 26
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 26
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 25
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 25
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 25
A dual role for genetically modified lymphocytes in cancer immunotherapy 25
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 24
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 23
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 23
A family of rapidly evolving genes from the sex reversal critical region in Xp21 23
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 23
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 22
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 22
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 22
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 21
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 21
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 21
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 21
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 21
Infusion of HSV-tk genetically-engineered donor lymphocytes restores anti-viral immunity early after allogeneic BMT. 20
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 20
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 20
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 20
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 20
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 20
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 20
Safety and Efficacy of Donor T Cells Engineered with Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK Cells) Given after T-Cell Depleted (TCD) Haploidentical Hematopoietic Transplantation (Haplo-HSCT): Results of a 14-Year Follow-Up in 45 Patients 19
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 19
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 19
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 19
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 19
Coronaviridae and SARS-associated coronavirus strain HSR1 19
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 18
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 18
Human insulin production and amelioration of diabetes in mice by electrotransfer-enhanced plasmid DNA gene transfer to the skeletal muscle 18
Improving the safety of cell therapy with the TK-suicide gene. 18
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 18
Attività citotossica e capacità di immunoregolazione dei macrofagi alveolari umani. 18
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 18
Terapia genica e malattia ereditaria 18
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 18
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 18
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 18
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 18
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 18
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency 18
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation 17
A new chance for SCID gene therapy 17
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 17
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 17
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 17
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 17
Suicide gene transduced T-cells for the regulation of the graft-versus-leukemia effect 17
Allogeneic transplants depleted of T-cells by soybean lectin agglutination and E rosette depletion. 17
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 17
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 17
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 16
Long term follow-up in 30 patients receiving HSV-TK transduced donor lymphocytes after allo-BMT. 16
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours 16
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 16
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 16
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 16
Genomic loss of mismatched HLA in leukemia is a major mechanism of in vivo escape from T cell immunosurveillance following haploidentical hematopoietic stem cell transplantation 16
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 16
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 16
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 16
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 16
Type 1 T regulatory cells 15
Gene therapy for adenosine deaminase deficiency 15
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 15
Inhibition of natural killer activity by human bronchoalveolar macrophages. 15
Changes in T-cell responses against human herpes virus-8 correlate with the disease course of latrogenic kaposi’s sarcoma in a patient with undifferentiated arthritis 15
Graft-versus-Tumor effect (GvT) in advanced solid tumors following reduced-intensity stem cell allografting and Donor Lymphocyte Infusion (DLI) 15
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 15
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 15
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement 15
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 15
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 15
Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA- Immunodeficient Patients 15
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor promoting neutrophils. 15
The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity 15
Clonal analyses of retroviral vector integrations in ADA-SCID patients treated with stem cell gene therapy 15
TRANSFER OF THE HSV-TK GENE INTO DONOR PERIPHERAL-BLOOD LYMPHOCYTES FOR IN-VIVO IMMUNOMODULATION OF DONOR ANTITUMOR IMMUNITY AFTER ALLO-BMT 15
The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice 15
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 15
Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites. 15
Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) 14
Totale 2.359
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Categoria #
all - tutte 92.133
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 92.133
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201 0 0 0 0 0 0 0 0 1 0 0 0
2020/20215 0 0 0 1 0 0 1 0 3 0 0 0
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.133 854 480 134 14 19 263 75 127 98 25 26 18
2023/2024997 66 60 98 158 60 195 54 65 6 52 44 139
2024/20251.321 593 67 49 137 111 345 19 0 0 0 0 0
Totale 4.806