IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
AS - Asia 7.669
EU - Europa 7.464
NA - Nord America 6.991
SA - Sud America 2.204
AF - Africa 156
Continente sconosciuto - Info sul continente non disponibili 134
OC - Oceania 26
Totale 24.644
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Nazione #
US - Stati Uniti d'America 6.579
RU - Federazione Russa 3.955
SG - Singapore 2.902
CN - Cina 2.468
BR - Brasile 1.809
SE - Svezia 1.180
IT - Italia 1.027
HK - Hong Kong 889
VN - Vietnam 705
FR - Francia 373
DE - Germania 235
CA - Canada 195
GB - Regno Unito 192
IN - India 153
AR - Argentina 147
BD - Bangladesh 147
FI - Finlandia 121
EC - Ecuador 91
IE - Irlanda 71
MX - Messico 68
AT - Austria 62
ID - Indonesia 62
JP - Giappone 62
NL - Olanda 60
ZA - Sudafrica 54
IQ - Iraq 50
PL - Polonia 39
TR - Turchia 38
CO - Colombia 36
ES - Italia 34
PY - Paraguay 34
JM - Giamaica 27
MA - Marocco 26
AU - Australia 24
CL - Cile 24
CR - Costa Rica 24
PK - Pakistan 22
VE - Venezuela 22
DZ - Algeria 19
PE - Perù 19
UA - Ucraina 19
UY - Uruguay 16
CH - Svizzera 15
SA - Arabia Saudita 15
UZ - Uzbekistan 15
EG - Egitto 14
HN - Honduras 14
MY - Malesia 14
SV - El Salvador 14
TN - Tunisia 14
NI - Nicaragua 13
KR - Corea 12
AE - Emirati Arabi Uniti 11
PR - Porto Rico 11
NP - Nepal 10
AZ - Azerbaigian 9
GT - Guatemala 9
IR - Iran 9
JO - Giordania 9
AL - Albania 8
IL - Israele 8
KZ - Kazakistan 8
PH - Filippine 8
TT - Trinidad e Tobago 8
CZ - Repubblica Ceca 7
LT - Lituania 7
RO - Romania 7
GR - Grecia 6
HU - Ungheria 6
KE - Kenya 6
PA - Panama 6
BB - Barbados 5
BE - Belgio 5
KG - Kirghizistan 5
KW - Kuwait 5
MD - Moldavia 5
NG - Nigeria 5
AM - Armenia 4
BH - Bahrain 4
BO - Bolivia 4
CY - Cipro 4
KH - Cambogia 4
MK - Macedonia 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
TW - Taiwan 4
BS - Bahamas 3
BY - Bielorussia 3
DM - Dominica 3
DO - Repubblica Dominicana 3
EE - Estonia 3
ET - Etiopia 3
NO - Norvegia 3
SC - Seychelles 3
XK - ???statistics.table.value.countryCode.XK??? 3
BA - Bosnia-Erzegovina 2
BG - Bulgaria 2
CI - Costa d'Avorio 2
CW - ???statistics.table.value.countryCode.CW??? 2
DK - Danimarca 2
Totale 24.476
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Città #
Singapore 1.028
Ashburn 1.026
Moscow 925
Hong Kong 872
San Jose 784
Dallas 556
Shanghai 457
Council Bluffs 402
Hefei 376
Princeton 371
Lawrence 370
Lauterbourg 325
Milan 312
Ho Chi Minh City 260
Beijing 222
New York 221
São Paulo 159
Hanoi 146
Santa Clara 137
Los Angeles 103
Helsinki 98
Phoenix 88
Rio de Janeiro 72
Dublin 68
Miano 65
Nuremberg 58
London 53
North Bergen 45
Tokyo 44
Rome 42
Brooklyn 41
Orem 41
Boardman 40
Quito 37
Pune 35
Atlanta 34
Boston 34
Belo Horizonte 33
Chicago 33
Guangzhou 33
Montreal 33
Vienna 32
Warsaw 32
Curitiba 30
Da Nang 30
Haiphong 29
Seattle 29
Washington 29
Brasília 28
Guayaquil 28
Porto Alegre 28
Toronto 26
Johannesburg 25
Manchester 24
Naples 24
Munich 23
Denver 22
Chennai 20
Frankfurt am Main 20
Houston 20
Philadelphia 20
Poplar 20
Thái Bình 20
Biên Hòa 19
Stockholm 19
Turku 19
Campinas 18
Las Vegas 18
Mexico City 18
Tianjin 18
Buffalo 17
Goiânia 17
Guarulhos 17
Salvador 17
San José 17
Santo André 16
Shenzhen 16
Hangzhou 15
The Dalles 15
Turin 15
Fortaleza 14
Hải Dương 14
Kingston 14
Montevideo 14
Mumbai 14
San Francisco 14
Baghdad 13
Dhaka 13
Lima 13
Monza 13
Winnipeg 13
Ankara 12
Cambridge 12
Can Tho 12
Cape Town 12
Columbus 12
Managua 12
Manaus 12
Montes Claros 12
Queens 12
Totale 11.186
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 456
Loss of mismatched HLA in leukemia after stem-cell transplantation 237
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 218
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 192
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 185
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 185
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 153
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 149
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 149
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 141
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 140
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 132
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 131
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 127
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 126
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 126
A dual role for genetically modified lymphocytes in cancer immunotherapy 126
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 126
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 123
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 122
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 121
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 118
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 118
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 117
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 116
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 113
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 111
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 111
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 110
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 110
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 109
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 107
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 107
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 104
A family of rapidly evolving genes from the sex reversal critical region in Xp21 102
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 102
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 101
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 101
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 99
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 98
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 98
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 97
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 95
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors 94
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 93
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 93
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 92
An in vivo model of somatic cell gene therapy for human severe combined immunodeficiency 92
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 91
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 91
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 91
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 89
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 88
The IL-1/IL-1 receptor axis and tumor cell released inflammasome adaptor ASC are key regulators of TSLP secretion by cancer associated fibroblasts in pancreatic cancer 88
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 87
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 87
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 85
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 82
Coronaviridae and SARS-associated coronavirus strain HSR1 82
A new chance for SCID gene therapy 81
Changes in T-cell responses against human herpes virus-8 correlate with the disease course of latrogenic kaposi’s sarcoma in a patient with undifferentiated arthritis 81
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours 81
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 78
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival 78
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 78
Targeting chemoresistant myeloid leukaemia and multiple myeloma through genetic redirection of T cells against CD44 variant 6. Presented at the 19th Annual Meeting of the European Society of Gene and Cellular Therapy 78
SUICIDE GENE TRANSFER INTO DONOR LYMPHOCYTES ALLOWS EARLY AND EFFECTIVE IMMUNE-RECONSTITUTION AFTER FAMILY HAPLOIDENTICAL HEMATOPOIETIC STEM CELL TRANSPLANTATION FOR LEUKEMIAS: RESULTS OF THE TK007 STUDY 78
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 77
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 75
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 75
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 75
Terapia genica e malattia ereditaria 75
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 75
The effect of donor-recipient KIR ligand incompatibility after haploidentical hematopoietic stem cell transplantation is overruled by biological characteristics of early reconstituting NK cells with impaired graft versus leukemia activity 75
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 74
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 74
Dual Transgenesis of T Cells with a CD44v6 CAR and a Suicide Gene for the Safe Eradication of Myeloid Leukemia and Myeloma 74
Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA- Immunodeficient Patients 74
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 73
Inhibition of natural killer activity by human bronchoalveolar macrophages. 73
Improving the safety of cell therapy with the TK-suicide gene. 73
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 73
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors 72
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 72
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 72
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 71
Safety of retroviral gene marking with a truncated NGF receptor 71
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 71
Extracellular NGFR spacers allow efficient tracking and enrichment of fully functional car-t cells co-expressing a suicide gene 71
Gene therapy for adenosine deaminase deficiency 70
Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells 70
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 69
Editing human lymphocyte specificity for safe and effective adoptive immunotherapy of leukemia 69
Temporal, quantitative and functional characteristics of Single-KIR positive alloreactive NK cell recovery account for impaired graft versus leukemia activity after haploidentical HSCT 69
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 69
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 68
Retroviral vector gene-transfer into donor peripheral-blood lymphocytes for in-vitro selection and in-vivo immunomodulation of donor antitumor immunity after allo-BMT 68
CD44v6 is associated with chemoresistance induced by bone marrow-derived mesenchymal stromal cells 68
Loss of Mismatched HLA as a Mechanism of Leukemia Immune Escape in Family Haploidentical and Unrelated HSCT: Analysis of 103 Transplants From Alternative Donors 68
STRUCTURAL BASIS FOR THE INTERATION OF ISODGR WITH RGD-BINDING SITE OF αvβ3 INTEGRIN 67
Totale 10.237
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Categoria #
all - tutte 173.994
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 173.994
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.133 854 480 134 14 19 263 75 127 98 25 26 18
2023/2024997 66 60 98 158 60 195 54 65 6 52 44 139
2024/20254.505 593 67 49 137 111 345 553 350 909 639 372 380
2025/202613.556 984 1.184 1.081 2.186 790 386 1.189 900 3.578 713 329 236
2026/20273.098 282 862 706 1.248 0 0 0 0 0 0 0 0
Totale 24.644