IRIS
BORDIGNON, CLAUDIO
 Distribuzione geografica
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Continente #
EU - Europa 1.600
NA - Nord America 1.376
AS - Asia 218
OC - Oceania 11
AF - Africa 10
SA - Sud America 9
Totale 3.224
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Nazione #
US - Stati Uniti d'America 1.367
SE - Svezia 1.159
IT - Italia 160
FI - Finlandia 98
CN - Cina 93
IE - Irlanda 66
IN - India 52
DE - Germania 47
GB - Regno Unito 26
JP - Giappone 20
SG - Singapore 17
FR - Francia 12
AU - Australia 9
CA - Canada 9
IR - Iran 8
DZ - Algeria 7
HK - Hong Kong 7
KR - Corea 7
RU - Federazione Russa 7
BR - Brasile 6
AT - Austria 4
CH - Svizzera 4
ES - Italia 4
NL - Olanda 4
AR - Argentina 3
IL - Israele 3
SA - Arabia Saudita 3
BG - Bulgaria 2
DK - Danimarca 2
EG - Egitto 2
ID - Indonesia 2
NO - Norvegia 2
NZ - Nuova Zelanda 2
PL - Polonia 2
TW - Taiwan 2
IQ - Iraq 1
MY - Malesia 1
NG - Nigeria 1
PH - Filippine 1
PK - Pakistan 1
UA - Ucraina 1
Totale 3.224
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Città #
Lawrence 371
Princeton 371
Ashburn 164
New York 104
Helsinki 98
Dublin 64
Milan 59
Shanghai 44
Pune 33
Washington 23
Los Angeles 17
Seattle 17
Borås 11
Hanover 9
London 7
Beijing 6
Cambridge 6
Hyderabad 6
Mountain View 6
Shijiazhuang 6
Falls Church 5
Naples 5
Overland Park 5
Perugia 5
Redwood City 5
Rome 5
San Jose 5
Santa Marinella 5
Turin 5
Chevy Chase 4
Delhi 4
Moreno Valley 4
Sydney 4
Tokyo 4
Vauderens 4
Aci Sant'Antonio 3
Algiers 3
Andover 3
Brisbane 3
Central 3
Chiyoda-ku 3
Florence 3
Genoa 3
Gijang-gun 3
Iowa City 3
Loughton 3
Moorestown 3
Oberndorf bei Salzburg 3
Paris 3
Park City 3
Philadelphia 3
Phoenix 3
Pomona 3
St Petersburg 3
Toronto 3
Verona 3
Winnipeg 3
Zanjan 3
Zhengzhou 3
Albuquerque 2
Athlone 2
Aurora 2
Belluno 2
Berlin 2
Bethesda 2
Birmingham 2
Bordeaux 2
Brooklyn 2
Buenos Aires 2
Castelli Calepio 2
Cherry Hill 2
Chicago 2
Copenhagen 2
Council Bluffs 2
Dayton 2
Daytona Beach 2
Ekimaedori 2
Falkenstein 2
Farmington 2
Ferrara 2
Gangnam-gu 2
Gorgonzola 2
Harrow 2
Hong Kong 2
Kingston upon Thames 2
Kolkata 2
Las Vegas 2
Livorno 2
L’Aquila 2
Madrid 2
Maple 2
Melbourne 2
Melendugno 2
Nagpur 2
Newtown 2
Palo Alto 2
Plovdiv 2
Roslindale 2
Ruislip 2
Salerno 2
Totale 1.645
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 175
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 58
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 55
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 51
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 34
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 28
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 28
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 28
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 26
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 22
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 21
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 20
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 20
Loss of mismatched HLA in leukemia after stem-cell transplantation 19
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 19
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 18
An approach to HIV gene therapy by transduction of multifunctional retroviral vectors in primary human T Lymphocytes 17
Infusion of HSV-tk genetically-engineered donor lymphocytes restores anti-viral immunity early after allogeneic BMT. 17
A family of rapidly evolving genes from the sex reversal critical region in Xp21 17
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 17
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 16
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 16
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 16
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 16
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 16
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 16
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 16
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 16
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 15
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 15
A clinical protocol for transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA deficient SCID 15
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 15
A human PBL immunodeficient mouse model for in vivo preclinical studies of human gene therapy. 15
24-hydroxycholesterol participates in pancreatic neuroendocrine tumor development 15
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 14
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 14
Acquisition of intact allogeneic HLA molecules by human dendritic cells. 14
Suicide gene transduced T-cells for the regulation of the graft-versus-leukemia effect 14
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 14
Safety and Efficacy of Donor T Cells Engineered with Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK Cells) Given after T-Cell Depleted (TCD) Haploidentical Hematopoietic Transplantation (Haplo-HSCT): Results of a 14-Year Follow-Up in 45 Patients 13
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 13
Graft-versus-Tumor effect (GvT) in advanced solid tumors following reduced-intensity stem cell allografting and Donor Lymphocyte Infusion (DLI) 13
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 13
Abrogation of prostaglandin E2/EP4 signaling impairs the development of rag1+ lymphoid precursors in the thymus of zebrafish embryos 13
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 13
A dual role for genetically modified lymphocytes in cancer immunotherapy 13
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 13
Alternative alla trasfusione di sangue omologo nel paziente chirurgico oncologico 13
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 13
Improving the antitumor activity of R-CHOP with NGR-hTNF in primary CNS lymphoma: Final results of a phase 2 trial 13
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 13
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 13
Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer 13
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation 12
Hematopoietic histoincompatibility reactions by NK cells in vitro: model for genetic resistance to marrow grafts 12
Clinical and molecular remissions can be achieved in advanced leukemias and lymphomas using reduced intensity conditioning followed by allografting of hematopoietc cells 12
Human insulin production and amelioration of diabetes in mice by electrotransfer-enhanced plasmid DNA gene transfer to the skeletal muscle 12
Long term follow-up in 30 patients receiving HSV-TK transduced donor lymphocytes after allo-BMT. 12
Various cells retrovirally transduced with N-acetylgalactosamine-6-sulphate sulphatase correct morquio skin fibroblasts in vitro 12
ACQUISITION OF INTACT ALLOGENEIC HUMAN LEUKOCYTE ANTIGEN MOLECULES BY HUMAN DENDRITIC CELLS 12
Improving the safety of cell therapy with the TK-suicide gene. 12
Clinical protocol: transfer of the ADA gene into bone marrow cells and peripheral blood lymphocytes for the treatment of patients affected by ADA-deficient SCID 12
Absence of metabolic cross-correction in Tay-Sachs cells: implication in gene therapy 12
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 12
Attività citotossica e capacità di immunoregolazione dei macrofagi alveolari umani. 12
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 12
Haploidentical HSCT: a 15-year experience at San Raffaele. 12
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 12
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 12
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 12
Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) 11
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors 11
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 11
Type 1 T regulatory cells 11
A new chance for SCID gene therapy 11
Gene therapy and apheresis 11
Les espoirs de la thérapie génique 11
Gene Therapy 11
Inhibition of natural killer activity by human bronchoalveolar macrophages. 11
Programmed infusions of Tk-transduced donor lymphocytes for immune reconstitution and relapse prevention in haplo-identical T-depleted SCT. 11
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 11
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms. 11
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 11
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 11
A direct gene transfer strategy via brain internal capsule reverses the biochemical defect in Tay-Sachs disease 11
Defining the optimal biological dose of NGR-hTNF, a selective vascular targeting agent, in advanced solid tumours 11
In vivo and in vitro models for the analysis of retroviral vector mediated expression of human ADA in ADA deficient cells from patients affected by severe combined immunodeficiency. 11
Terapia genica e malattia ereditaria 11
Phase I study of NGR-hTNF, a selective vascular targeting agent, in combination with cisplatin in refractory solid tumors. 11
The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor promoting neutrophils. 11
Clinical and immunologic responses in melanoma patients vaccinated with MAGE-A3-genetically modified lymphocytes 11
Clonal analyses of retroviral vector integrations in ADA-SCID patients treated with stem cell gene therapy 11
TRANSFER OF THE HSV-TK GENE INTO DONOR PERIPHERAL-BLOOD LYMPHOCYTES FOR IN-VIVO IMMUNOMODULATION OF DONOR ANTITUMOR IMMUNITY AFTER ALLO-BMT 11
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 11
Factors affecting efficacy of HSV-TK-transduced donor peripheral blood lymphocytes after allo-BMT. 11
The administration of drugs inhibiting cholesterol/oxysterol synthesis is safe and increases the efficacy of immunotherapeutic regimens in tumor-bearing mice 11
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 11
Natural cytotoxicity on tumour cells of human macrophages obtained from diverse anatomical sites. 11
Efficient gene transfer into primitive hematopoietic progenitores using a bone marrow microenvironment cell line engineered to produce retroviral vectors 10
Graft failures after T cell depleted marrow tranplants for leukemia: clinical and in vitro characteristics. 10
Totale 1.692
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Categoria #
all - tutte 61.438
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 61.438
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202019 15 1 0 2 0 0 0 0 1 0 0 0
2020/20215 0 0 0 1 0 0 1 0 3 0 0 0
2021/2022283 0 0 0 125 22 14 8 16 7 62 5 24
2022/20232.140 858 482 134 14 19 264 75 127 98 25 26 18
2023/2024857 66 60 99 159 64 195 54 65 6 52 37 0
Totale 3.352