Extending the interval between the end of neoadjuvant chemoradiotherapy (CRT) and surgery may enhance tumor response in patients with locally advanced rectal cancer. However, data on the association of delaying surgery with long-term outcome in patients who had a minor or poor response are lacking.
Association of Delayed Surgery With Oncologic Long-term Outcomes in Patients With Locally Advanced Rectal Cancer Not Responding to Preoperative Chemoradiation / Deidda, Simona; Elmore, Ugo; Rosati, Riccardo; De Nardi, Paola; Vignali, Andrea; Puccetti, Francesco; Spolverato, Gaya; Capelli, Giulia; Zuin, Matteo; Muratore, Andrea; Danna, Riccardo; Calabrò, Marcello; Guerrieri, Mario; Ortenzi, Monica; Ghiselli, Roberto; Scabini, Stefano; Aprile, Alessandra; Pertile, Davide; Sammarco, Giuseppe; Gallo, Gaetano; Sena, Giuseppe; Coco, Claudio; Rizzo, Gianluca; Pafundi, Donato Paolo; Belluco, Claudio; Innocente, Roberto; Degiuli, Maurizio; Reddavid, Rossella; Puca, Lucia; Delrio, Paolo; Rega, Daniela; Conti, Pietro; Pastorino, Alessandro; Zorcolo, Luigi; Pucciarelli, Salvatore; Aschele, Carlo; Restivo, Angelo. - In: JAMA SURGERY. - ISSN 2168-6254. - 156:12(2021), pp. 1141-1149. [10.1001/jamasurg.2021.4566]
Association of Delayed Surgery With Oncologic Long-term Outcomes in Patients With Locally Advanced Rectal Cancer Not Responding to Preoperative Chemoradiation
Elmore, UgoSecondo
;Rosati, Riccardo;Vignali, Andrea;Puccetti, Francesco;
2021-01-01
Abstract
Extending the interval between the end of neoadjuvant chemoradiotherapy (CRT) and surgery may enhance tumor response in patients with locally advanced rectal cancer. However, data on the association of delaying surgery with long-term outcome in patients who had a minor or poor response are lacking.| File | Dimensione | Formato | |
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