IRIS
6 Brevetti
 Distribuzione geografica
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Continente #
EU - Europa 3.511
AS - Asia 3.293
NA - Nord America 2.579
SA - Sud America 837
Continente sconosciuto - Info sul continente non disponibili 81
AF - Africa 67
OC - Oceania 1
Totale 10.369
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Nazione #
US - Stati Uniti d'America 2.445
RU - Federazione Russa 1.992
SG - Singapore 1.309
CN - Cina 1.037
BR - Brasile 674
SE - Svezia 629
HK - Hong Kong 388
VN - Vietnam 304
IT - Italia 251
FR - Francia 187
DE - Germania 160
FI - Finlandia 109
IN - India 79
CA - Canada 71
GB - Regno Unito 58
AR - Argentina 57
ZA - Sudafrica 34
EC - Ecuador 31
MX - Messico 30
CO - Colombia 29
BD - Bangladesh 28
PL - Polonia 27
ID - Indonesia 24
IQ - Iraq 23
NL - Olanda 21
ES - Italia 13
PY - Paraguay 13
TR - Turchia 12
UA - Ucraina 12
AT - Austria 11
CL - Cile 10
VE - Venezuela 10
IR - Iran 9
JP - Giappone 9
MA - Marocco 9
PK - Pakistan 9
RO - Romania 9
AE - Emirati Arabi Uniti 7
JM - Giamaica 6
KE - Kenya 6
KZ - Kazakistan 6
SA - Arabia Saudita 6
TN - Tunisia 6
UY - Uruguay 6
IE - Irlanda 5
JO - Giordania 5
MY - Malesia 5
OM - Oman 5
AZ - Azerbaigian 4
CH - Svizzera 4
EG - Egitto 4
IL - Israele 4
PA - Panama 4
PE - Perù 4
UZ - Uzbekistan 4
AL - Albania 3
BO - Bolivia 3
CR - Costa Rica 3
CZ - Repubblica Ceca 3
DO - Repubblica Dominicana 3
ET - Etiopia 3
RS - Serbia 3
TT - Trinidad e Tobago 3
AM - Armenia 2
BH - Bahrain 2
BY - Bielorussia 2
DZ - Algeria 2
GT - Guatemala 2
HN - Honduras 2
LT - Lituania 2
MD - Moldavia 2
NP - Nepal 2
PH - Filippine 2
PR - Porto Rico 2
SV - El Salvador 2
TW - Taiwan 2
BE - Belgio 1
BG - Bulgaria 1
BS - Bahamas 1
CG - Congo 1
CI - Costa d'Avorio 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
HR - Croazia 1
KN - Saint Kitts e Nevis 1
LB - Libano 1
LC - Santa Lucia 1
MK - Macedonia 1
NI - Nicaragua 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PT - Portogallo 1
QA - Qatar 1
SI - Slovenia 1
SN - Senegal 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TL - Timor Orientale 1
VG - Isole Vergini Britanniche 1
Totale 10.288
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Città #
Dallas 550
Singapore 432
Moscow 395
Hong Kong 383
Ashburn 245
Shanghai 243
San Jose 212
Council Bluffs 182
Hefei 174
Beijing 152
Lauterbourg 148
Lawrence 136
Princeton 136
Ho Chi Minh City 107
Helsinki 83
New York 78
Hanoi 62
São Paulo 58
Los Angeles 55
Milan 54
Orem 51
Santa Clara 35
Munich 34
Washington 29
Turku 24
Boardman 23
Bologna 23
Pune 23
Warsaw 23
Ancona 22
Guangzhou 20
Chennai 19
Denver 19
Johannesburg 19
Rio de Janeiro 19
Da Nang 18
Montreal 18
Nuremberg 18
Rome 18
Brooklyn 16
Stockholm 16
Brasília 15
Curitiba 15
Poplar 15
Toronto 15
Atlanta 14
Guarulhos 13
Haiphong 13
Baghdad 12
Guayaquil 12
Houston 12
Hải Dương 12
London 12
Mexico City 12
Phoenix 12
Quito 11
Amsterdam 10
Campinas 10
Chicago 10
Dhaka 10
Frankfurt am Main 10
Manchester 10
Miami 10
Perugia 10
Shenzhen 10
Tokyo 9
Bogotá 8
Cape Town 8
Naples 8
New Delhi 8
Porto Alegre 8
Seattle 8
Turin 8
Boston 7
Buenos Aires 7
Hangzhou 7
Nova Iguaçu 7
Tianjin 7
Charlotte 6
Falkenstein 6
Nairobi 6
Piracicaba 6
Salvador 6
San Francisco 6
Santo André 6
São Bernardo do Campo 6
Thái Bình 6
Thái Nguyên 6
Asunción 5
Fortaleza 5
Limeira 5
Manaus 5
Montevideo 5
Ottawa 5
Santiago de Cali 5
Tehran 5
Amman 4
Ankara 4
Baku 4
Belo Horizonte 4
Totale 4.873
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Nome #
System for physical activity, and related method 239
[Severe aortic stenosis successfully treated with percutaneous aortic valve implantation] 157
Ablation catheter with flexible tip and methods of making the same 128
2) HERV-H per l'uso come marcatore molecolare del Disturbo dello Spettro Autistico e relativo metodo diagnostico in vitro, kit diagnostico e usi medici (2012).GAUDI S F 118
Permanent Epigenetic Gene Silencing 115
SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS 111
INCREASE OF MYELOID MICROVESICLES IN THE CEREBROSPINAL FLUID AS BIOMARKER OF MICROGLIA/MACROPHAGE ACTIVATION IN NEUROLOGICAL DISORDERS 106
GENE SILENCING 105
RECOMBINANT LENTIVIRAL VECTOR FOR STEM CELL-BASED GENE THERAPY OF SICKLE CELL DISORDER 104
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION 104
Treatment and Prevention of Cancer with HMGB1 Antagonists 101
ACETYLATED HMGB1 PROTEIN 101
Sistema per svolgere attività fisica, e relativo procedimento 100
Use of HMGB2 and HMGB3 proteins for medical applications 97
HMGB1 inhibitors and antagonista for the inhibition of atherosclerosis pathogenesis and development 96
Dispositivo di cannulazione vascolare 96
Adjuvant incorporation in immunoanotherapeutics 90
VIRAL VECTOR COMBINING GENE THERAPY AND GENOME EDITING APPROACHES FOR GENE THERAPY OF GENETIC DISORDERS 89
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells 88
Novel biomarkers 83
HMGB1 protein inhibitors for the regulation of smooth muscle cells and endothelial cells proliferation 83
VECTOR PRODUCTION 80
PROCEDIMENTO E SISTEMA PER LA RILEVAZIONE DI RISPOSTE BINARIE TRAMITE ANALISI DEL DIAMETRO PUPILLARE DI UN SOGGETTO 78
Methods and compositions for targeted integration 76
Agents regulating vascular permeability 75
Formulations to administer SUMO2/3 73
Spinginodo 71
Bottone anastomotico frammentabile 69
Inhibitors of hepatitis B virus 68
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 67
Structure and function of the salicyclic acid binding sites on human hmgb1 and methods of use thereof for the rational design of both salicyclic acid derivatives and other agents that alter animal and plant hmgbs activities 67
MEZZO PER VEDERE UNA VALVOLA CARDIACA IN FASE INTRAOPERATORIA 66
Method for the preparation of new oligoclonal antibodies 65
Tricuspid valve repair using tension 65
Anti-idiotype monoclonal antibodies as mimotopes of the HIV gp120 antigen 64
Use of IL-7 and IL-15 for the genetic modification of memory T lymphocytes 64
Vaccine nanotechnology 64
Anti-idiotype monoclonal antibody directed against anti-TNF antibodies 63
Hmgb1 variants and uses thereof 63
Delivery tool for implantation of spool assembly coupled to a helical anchor 63
Collagen Scaffold in nervous system regeneration 62
Monoclonal antibodies against the TNF type-I receptor, process for their production and use thereofAnticorpi monoclonali anti-recettore di tipo 1 del TNF alfa, procedimento per la loro produzione e loro uso 62
Dispositivo per la chirurgia endoscopica transanale 62
Tricyclic inhibitors of hepatitis B virus 62
Human monoclonal recombinant antibody against NS3 HCV protein and methods therefor 61
Cytokine conjugates (IL-12 –peptide conjugates) 61
Suturatrice meccanica circolare 61
Monoclonal antibodies having homosubtype cross-neutralization properties against influenza A viruses subtype H1 61
Cyclic inhibitors of hepatitis B virus 61
Anti-urokinase monoclonal antibody, matrix bearing it, test method, biochemical test kits which use it. 60
Phage Display Technology 60
Cromogranina A per uso come reagente in un metodo diagnostico o prognostico 60
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen 60
Monoclonal antibodies as a medicament for the therapeutic and/or prophylactic treatment of swine-origin influenza A (H1N1) virus (S-OIV) infections 59
Method and apparatus for tricuspid valve repair using tension 59
“Non-invasive ventilation mask and use thereof” 59
Magnetically Guided Catheter With Flexible Tip 59
INFLUENZA VIRUS AND TYPE 1 DIABETES 59
DISPOSITIVO PER USO IN EMODINAMICA 59
Selective immunoassay for the detection of pro-urokinase and urokinase 58
Fusion of cytokines and targeting peptides 58
Receptor-antibody sandwich assay. 58
Methods for treating cardiac reperfusion injury 58
Control for a Remote Navigation System 58
PROTESI ANULARE PER VALVOLA MITRALE 58
Suturatrice meccanica circolare 57
Suturatrice automatica per borsa di tabacco 57
Method of treating cardiac arrhythmias 57
System and methods for locating and ablating arrhythomogenic tissues 57
Nicotine immunonanotherapeutics 57
Targeting of antigen presenting cells with immunonanotherapeutics 57
RETAINING MECHANISMS FOR PROSTHETIC VALVES 57
Immobilized oligopeptides 56
Liver gene expression associated with the inhibition of HBV replication or transcription 56
Irrigated Catheter with Improved fluid flow 56
CARDIAC TISSUE CINCHING 56
FOSSA OVALIS PENETRATION USING PROBING ELEMENTS 56
FOSSA OVALIS PENETRATION APPARATUS 56
Real heart case simulator 56
SULFONAMIDES USEFUL IN THE PREVENTION OF DIABETES 55
Dispositivo anastomotico ad anelli 55
Human Monoclonal Antibody Fab Fragments directed against HCV E2 glycoprotein and endowed with neutralizing activity 54
Réparation de valve tricuspide à l'aide d'une tension 54
Strumento automatico per suture a borsa di tabacco 54
Dispositivo ad anelli frammentabili 54
Anti-HCV monoclonal antibody as a medicament for the therapeutic treatment and prevention of HCV infections 54
System and Network for Remote Medical Procedures 54
Multi-Electrode Irrigated Balloon Catheter 54
METHOD AND SYSTEM FOR DETECTING VOLUNTARY BINARY RESPONSES BY ANALYZING THE PUPIL DIAMETER OF A SUBJECT 54
SUMO and uses thereof 54
PERCUTANEOUS TETHER LOCKING 54
IMPLANTATION OF REPAIR CHORDS IN THE HEART 54
Non linear peptides hydropathically complementary to know amino acid sequences, process for the production and used thereof 53
INHIBITORS OF CXCR1/2 AS ADJUVANTS IN THE TRANSPLANT OF PANCREATIC ISLETS 53
Dispositivo anastomotico ad anelli 53
Combination product (Use of IDO inhibitors in cancer therapy with targeted interferon gamma) 52
Strumento automatico per suture a borsa di tabacco 52
Solid-phase receptor assay for antibiotics of the vancomycin class. 52
Modified cytokines for therapeutic use 52
Use of common gamma-chain cytokines for the visualization, isolation and genetic modification of memory T lymphocytes 52
Totale 7.021
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022138 0 0 0 84 4 4 3 9 10 12 6 6
2022/2023933 299 260 109 3 1 113 8 36 58 11 15 20
2023/2024473 40 11 132 32 23 46 12 29 0 31 12 105
2024/20252.186 259 38 61 86 33 166 320 158 351 224 252 238
2025/20266.214 480 602 500 898 474 171 488 449 1.730 312 70 40
2026/2027394 202 192 0 0 0 0 0 0 0 0 0 0
Totale 10.369