IRIS
SITIA, ROBERTO
 Distribuzione geografica
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Continente #
NA - Nord America 3.911
EU - Europa 3.825
AS - Asia 3.723
SA - Sud America 980
Continente sconosciuto - Info sul continente non disponibili 237
AF - Africa 76
OC - Oceania 7
Totale 12.759
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Nazione #
US - Stati Uniti d'America 3.695
RU - Federazione Russa 2.224
SG - Singapore 1.350
CN - Cina 1.221
BR - Brasile 823
SE - Svezia 513
IT - Italia 481
HK - Hong Kong 454
VN - Vietnam 341
FR - Francia 176
DE - Germania 111
CA - Canada 90
IN - India 86
GB - Regno Unito 76
FI - Finlandia 53
BD - Bangladesh 51
AR - Argentina 46
AT - Austria 36
MX - Messico 36
PL - Polonia 31
TR - Turchia 31
JP - Giappone 28
ID - Indonesia 25
IQ - Iraq 25
IE - Irlanda 24
CO - Colombia 23
EC - Ecuador 23
NL - Olanda 21
ZA - Sudafrica 21
VE - Venezuela 19
ES - Italia 17
JM - Giamaica 17
PY - Paraguay 15
UZ - Uzbekistan 15
CR - Costa Rica 12
MA - Marocco 12
PK - Pakistan 12
RO - Romania 12
PE - Perù 11
CL - Cile 10
HN - Honduras 10
LT - Lituania 10
MY - Malesia 10
SV - El Salvador 10
AE - Emirati Arabi Uniti 9
KE - Kenya 9
SA - Arabia Saudita 9
UA - Ucraina 9
EG - Egitto 8
NI - Nicaragua 7
BE - Belgio 6
KR - Corea 6
TN - Tunisia 6
AU - Australia 5
AZ - Azerbaigian 5
DO - Repubblica Dominicana 5
GT - Guatemala 5
PH - Filippine 5
PR - Porto Rico 5
UY - Uruguay 5
BO - Bolivia 4
MK - Macedonia 4
NP - Nepal 4
TT - Trinidad e Tobago 4
BB - Barbados 3
BN - Brunei Darussalam 3
CI - Costa d'Avorio 3
ET - Etiopia 3
GD - Grenada 3
GP - Guadalupe 3
IL - Israele 3
JO - Giordania 3
MD - Moldavia 3
NG - Nigeria 3
OM - Oman 3
PS - Palestinian Territory 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
TH - Thailandia 3
AO - Angola 2
BG - Bulgaria 2
BH - Bahrain 2
CW - ???statistics.table.value.countryCode.CW??? 2
DZ - Algeria 2
IR - Iran 2
KG - Kirghizistan 2
LB - Libano 2
NZ - Nuova Zelanda 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BS - Bahamas 1
BY - Bielorussia 1
BZ - Belize 1
CM - Camerun 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
HT - Haiti 1
Totale 12.505
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Città #
Ashburn 658
Singapore 528
San Jose 506
Moscow 490
Hong Kong 449
Dallas 294
Shanghai 209
Council Bluffs 204
Milan 185
Hefei 184
Princeton 176
Lawrence 175
Lauterbourg 156
Ho Chi Minh City 124
New York 122
Beijing 106
Santa Clara 86
Los Angeles 83
Hanoi 69
São Paulo 67
Phoenix 42
Washington 42
Orem 35
Helsinki 31
The Dalles 31
Warsaw 30
Boardman 29
Guangzhou 29
Belo Horizonte 26
Pune 26
Rio de Janeiro 26
Atlanta 25
Chicago 25
Miano 25
Nuremberg 24
Stockholm 24
Dublin 23
Montreal 23
Munich 23
Tokyo 21
Brooklyn 20
Boston 19
Houston 19
Rome 19
Columbus 17
London 17
San Francisco 17
Turku 17
Denver 16
Vienna 16
Campinas 15
Chennai 14
Da Nang 14
Poplar 14
Seattle 14
Brasília 13
Mexico City 13
Porto Alegre 13
Ankara 12
Johannesburg 12
Naples 12
Tashkent 12
Haiphong 11
North Bergen 11
Quito 11
San José 11
Toronto 11
Kingston 10
Manchester 10
Newark 10
Amsterdam 9
Biên Hòa 9
Dhaka 9
Hangzhou 9
Lima 9
San Salvador 9
Shenzhen 9
Buffalo 8
Florence 8
Frankfurt am Main 8
Mumbai 8
Nairobi 8
Tianjin 8
Uberlândia 8
Baghdad 7
Betim 7
Caracas 7
Charlotte 7
Curitiba 7
Genoa 7
Goiânia 7
Las Vegas 7
Managua 7
Nha Trang 7
Palermo 7
Ribeirão Preto 7
Salvador 7
Santiago 7
Sorocaba 7
Thái Bình 7
Totale 6.082
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Nome #
CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells 164
A pH-Regulated Quality Control Cycle for Surveillance of Secretory Protein Assembly 127
A RIDDle solved: why an intact IRE1α/XBP-1 signaling relay is key for humoral immune responses 127
A dynamic study of protein secretion and aggregation in the secretory pathway 127
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria 125
Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics. 123
A peptide extension dictates IgM polymerization 120
MHC Class II Transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity 120
Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum-Mitochondria Interface (MAM) 119
Iron increases the susceptibility of multiple myeloma cells to bortezomib 114
ANTIBODY SYNTHESIS AND ASSEMBLY 114
Profound architectural and functional readjustments of the secretory pathway in decidualization of endometrial stromal cells 114
A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment 113
Progressive quality control of secretory proteins in the early secretory compartment by ERp44 112
A novel pathway for secretory proteins? 111
Progressive waves of IL-1β release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways 111
Inadequate BiP availability defines endoplasmic reticulum stress 111
Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome 111
Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks 111
Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors 109
Plasma cells require autophagy for sustainable immunoglobulin production 106
A New Fluorogenic Peptide Determines Proteasome Activity in Single Cells 106
Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 105
Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail 105
A computer-driven approach to PCR-based differential screening, alternative to differential display 104
Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44 104
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 100
Mechanisms of Oxidative Protein Folding and Thiol-Dependent Quality Control: Tales of Cysteines and Cystines, Tiziana Anelli and Roberto Sitia 100
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway 100
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells 99
Pathogenesis of ER Storage Disorders: Modulating Russell Body Biogenesis by Altering Proximal and Distal Quality Control 98
Aggresomes and Russell bodies. Symptoms of cellular indigestion? 96
Biochemical nature of Russell Bodies. 96
Aspects of gene regulation during the unfolded protein response in human cells 95
Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants. 94
A novel secretory pathway for interleukin 1ß, a protein lacking a signal sequence 93
ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family 93
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation 92
Author Correction: Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 91
Dampening Ab responses using proteasome inhibitors following in vivo B cell activation 91
A persulfidation-based mechanism controls aquaporin-8 conductance 91
Physiology and pathology of proteostasis in the early secretory compartment 90
Two conserved cysteine triads in human Ero1alpha cooperate for efficient disulfide bond formation in the endoplasmic reticulum 89
Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane 81
A spatial association between membrane IgD and the receptor for C3b (CR1) at the cell surface of murine B lymphocytes 80
Regulation of calcium fluxes by GPX8, a type-II transmembrane peroxidase enriched at the mitochondria-associated endoplasmic reticulum membrane 80
Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway 80
Peroxides and Peroxidases in the Endoplasmic Reticulum: Integrating Redox Homeostasis and Oxidative Folding 79
Stress regulates aquaporin-8 permeability to impact cell growth and survival 79
The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha 79
A novel secretory pathway with possible implications in antigen processing and presentation 78
Glutathione peroxidase 7 utilizes hydrogen peroxide generated by Ero1a to promote oxidative folding 75
Molecular bases of cyclic and specific disulfide interchange between human ERO1alpha protein and protein-disulfide isomerase (PDI). 75
Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude 75
Proteostasis and "redoxtasis" in the secretory pathway: Tales of tails from ERp44 and immunoglobulins. 75
B- to Plasma-Cell Terminal Differentiation Entails Oxidative Stress and Profound Reshaping of the Antioxidant Responses 74
The endoplasmic reticulum: a dynamic patchwork of specialized subregions 72
Sialylation of N-Linked Glycans Influences the Immunomodulatory Effects of IgM on T Cells 71
The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19 71
IRON CONTRIBUTES TO BORTEZOMIB SENSITIVITY IN MULTIPLE MYELOMA CELLS 70
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44 70
Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents 70
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion 70
Protein quality control in the early secretory pathway 70
Crystal structures of human Ero1α reveal the mechanisms of regulated and targeted oxidation of PDI 70
Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity 70
CD36 is a ditopic glycoprotein with the N-Terminal domain implicated in intracellular transport 69
Expression of mutant or cytosolic PrP in transgenic mice and cells is not associated with endoplasmic reticulum stress or proteasome dysfunction. 69
Dysregulated IL-1β Secretion in Autoinflammatory Diseases: A Matter of Stress? 69
The endoplasmic reticulum 69
Expression of a receptor for sheep erythrocytes by B lymphocytes from a chronic lymphocytic leukemia patient. 68
Cellular stress 68
Monitoring cytosolic H2O2 fluctuations arising from altered plasma membrane gradients or from mitochondrial activity 68
The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation 68
Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface 68
Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages 68
Tyrosine kinase signal modulation: a matter of H2O2 membrane permeability? 67
Increased TG lymphocytes in a case of Congenital Hypoplastic Anemia (Blackfan-Diamond Syndrome) 67
Stress as an intercellular signal: the emergence of stress associated molecular patterns (SAMP) 67
Role of the early secretory pathway in SARS-CoV-2 infection 67
Oxidative protein folding in the secretory pathway and redox-signaling across compartments and cells 66
PROGRESSIVELY IMPAIRED PROTEASOMAL CAPACITY DURING TERMINAL PLASMA CELL DIFFERENTIATION 66
Synthesis and processing of the a heavy chains of secreted and membrane-bound IgA 65
Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum 65
Expression of two immunoglobulin isotypes, IgM and IgA, with identical idiotype in the B cell lymphoma I.29 64
Crystal structure of the ERp44-peroxiredoxin 4 complex reveals the molecular mechanisms of thiol-mediated protein retention 64
Different redox sensitivity of endoplasmic reticulum associated degradation clients suggests a novel role for disulphide bonds in secretory proteins 64
Chemo-metabolic regulation of immune responses by Tregs 63
KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23 63
Mitochondrial Aquaporin-8: A Functional Peroxiporin? Response to Marinelli and Marchissio 63
Stress, protein (mis)folding, and signaling: the redox connection 62
Quality control in the endoplasmic reticulum protein factory 61
Manipulation of Oxidative Protein Folding and PDI Redox State in Mammalian Cells 61
Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. 61
Dynamic regulation of Ero1α and Prx4 localization in the secretory pathway* 61
Quality control of ER synthetized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation 60
Sequential steps and checkpoints in the early exocytic compartment during secretory IgM biogenesis 60
Role of SELENOF as a gatekeeper of secreted disulfide-rich glycoproteins 60
High rates of thioredoxin secretion correlate with growth arrest in hepatoma cells 59
COLTURE CELLULARI: TECNICHE DI BASE E APPLICAZIONI IN ONCOLOGIA 59
Totale 8.534
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Categoria #
all - tutte 85.525
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 85.525
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202266 0 0 0 23 1 3 9 0 12 2 6 10
2022/2023937 380 228 57 16 5 119 19 59 27 7 2 18
2023/2024563 6 23 66 32 54 168 26 53 1 31 30 73
2024/20252.282 259 29 43 75 74 217 276 175 419 348 172 195
2025/20267.131 530 518 432 1.074 484 216 739 555 1.960 391 84 148
2026/20271.544 172 369 347 656 0 0 0 0 0 0 0 0
Totale 12.759