IRIS
SITIA, ROBERTO
 Distribuzione geografica
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Continente #
AS - Asia 3.633
EU - Europa 3.525
NA - Nord America 2.702
SA - Sud America 964
AF - Africa 75
OC - Oceania 7
Totale 10.906
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Nazione #
US - Stati Uniti d'America 2.585
RU - Federazione Russa 2.223
SG - Singapore 1.330
CN - Cina 1.187
BR - Brasile 817
SE - Svezia 513
HK - Hong Kong 443
VN - Vietnam 336
IT - Italia 206
FR - Francia 176
DE - Germania 111
IN - India 86
GB - Regno Unito 68
CA - Canada 54
FI - Finlandia 53
AR - Argentina 46
BD - Bangladesh 41
AT - Austria 36
MX - Messico 34
PL - Polonia 30
TR - Turchia 30
JP - Giappone 26
ID - Indonesia 25
IQ - Iraq 25
IE - Irlanda 24
ZA - Sudafrica 21
CO - Colombia 20
EC - Ecuador 20
NL - Olanda 20
VE - Venezuela 17
ES - Italia 16
PY - Paraguay 15
UZ - Uzbekistan 15
MA - Marocco 12
PK - Pakistan 12
CL - Cile 10
LT - Lituania 10
PE - Perù 10
AE - Emirati Arabi Uniti 9
KE - Kenya 9
SA - Arabia Saudita 9
EG - Egitto 8
MY - Malesia 7
UA - Ucraina 7
KR - Corea 6
TN - Tunisia 6
AU - Australia 5
AZ - Azerbaigian 5
JM - Giamaica 5
UY - Uruguay 5
BE - Belgio 4
CR - Costa Rica 4
DO - Repubblica Dominicana 4
MK - Macedonia 4
NP - Nepal 4
PH - Filippine 4
BN - Brunei Darussalam 3
BO - Bolivia 3
CI - Costa d'Avorio 3
ET - Etiopia 3
IL - Israele 3
JO - Giordania 3
MD - Moldavia 3
OM - Oman 3
PS - Palestinian Territory 3
RO - Romania 3
SK - Slovacchia (Repubblica Slovacca) 3
SN - Senegal 3
SV - El Salvador 3
TT - Trinidad e Tobago 3
AO - Angola 2
BB - Barbados 2
BG - Bulgaria 2
BH - Bahrain 2
DZ - Algeria 2
HN - Honduras 2
IR - Iran 2
KG - Kirghizistan 2
LB - Libano 2
NG - Nigeria 2
NZ - Nuova Zelanda 2
PR - Porto Rico 2
RS - Serbia 2
SY - Repubblica araba siriana 2
TW - Taiwan 2
AL - Albania 1
BA - Bosnia-Erzegovina 1
BY - Bielorussia 1
CM - Camerun 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
GT - Guatemala 1
HU - Ungheria 1
IS - Islanda 1
KW - Kuwait 1
KZ - Kazakistan 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MG - Madagascar 1
MN - Mongolia 1
Totale 10.895
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Città #
Singapore 513
Moscow 490
Hong Kong 441
Ashburn 431
San Jose 404
Dallas 290
Shanghai 208
Hefei 184
Lawrence 175
Princeton 175
Lauterbourg 156
Ho Chi Minh City 123
New York 120
Beijing 95
Milan 91
Los Angeles 76
Hanoi 68
São Paulo 67
Santa Clara 42
Orem 35
Helsinki 31
Washington 31
Boardman 29
Guangzhou 29
Warsaw 29
Belo Horizonte 26
Pune 26
Rio de Janeiro 25
Nuremberg 24
Stockholm 24
Dublin 23
Munich 23
Montreal 22
The Dalles 21
Tokyo 21
Boston 18
Brooklyn 17
Columbus 17
Houston 17
Turku 17
Chicago 16
London 16
Vienna 16
Campinas 15
Atlanta 14
Chennai 14
Da Nang 14
Denver 14
Phoenix 14
Poplar 14
Brasília 13
Council Bluffs 13
Porto Alegre 13
San Francisco 13
Ankara 12
Johannesburg 12
Seattle 12
Tashkent 12
Haiphong 11
Mexico City 11
Biên Hòa 9
Dhaka 9
Hangzhou 9
Manchester 9
Shenzhen 9
Amsterdam 8
Frankfurt am Main 8
Lima 8
Mumbai 8
Nairobi 8
Newark 8
Quito 8
Tianjin 8
Toronto 8
Uberlândia 8
Baghdad 7
Betim 7
Caracas 7
Curitiba 7
Goiânia 7
Nha Trang 7
Ribeirão Preto 7
Salvador 7
Santiago 7
Sorocaba 7
Thái Bình 7
Trento 7
Aracaju 6
Contagem 6
Dubai 6
Guarulhos 6
Halle 6
Hanover 6
New Delhi 6
Querétaro 6
Recife 6
Shijiazhuang 6
São Bernardo do Campo 6
Baku 5
Bauru 5
Totale 5.208
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Nome #
CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells 154
A RIDDle solved: why an intact IRE1α/XBP-1 signaling relay is key for humoral immune responses 121
A pH-Regulated Quality Control Cycle for Surveillance of Secretory Protein Assembly 113
A dynamic study of protein secretion and aggregation in the secretory pathway 112
Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics. 107
A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment 105
Profound architectural and functional readjustments of the secretory pathway in decidualization of endometrial stromal cells 105
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria 103
Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum-Mitochondria Interface (MAM) 103
Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks 103
A novel pathway for secretory proteins? 101
ANTIBODY SYNTHESIS AND ASSEMBLY 101
Progressive quality control of secretory proteins in the early secretory compartment by ERp44 99
A peptide extension dictates IgM polymerization 99
Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail 99
Inadequate BiP availability defines endoplasmic reticulum stress 99
MHC Class II Transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity 99
Iron increases the susceptibility of multiple myeloma cells to bortezomib 97
A New Fluorogenic Peptide Determines Proteasome Activity in Single Cells 97
A computer-driven approach to PCR-based differential screening, alternative to differential display 96
Mechanisms of Oxidative Protein Folding and Thiol-Dependent Quality Control: Tales of Cysteines and Cystines, Tiziana Anelli and Roberto Sitia 96
Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors 94
Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome 94
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells 92
Biochemical nature of Russell Bodies. 90
Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44 90
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 89
Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 88
Aggresomes and Russell bodies. Symptoms of cellular indigestion? 88
ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family 88
Aspects of gene regulation during the unfolded protein response in human cells 87
Plasma cells require autophagy for sustainable immunoglobulin production 85
Physiology and pathology of proteostasis in the early secretory compartment 84
A novel secretory pathway for interleukin 1ß, a protein lacking a signal sequence 83
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation 83
Pathogenesis of ER Storage Disorders: Modulating Russell Body Biogenesis by Altering Proximal and Distal Quality Control 82
Author Correction: Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 81
Dampening Ab responses using proteasome inhibitors following in vivo B cell activation 81
A persulfidation-based mechanism controls aquaporin-8 conductance 80
Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants. 79
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway 77
The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha 74
Regulation of calcium fluxes by GPX8, a type-II transmembrane peroxidase enriched at the mitochondria-associated endoplasmic reticulum membrane 74
A spatial association between membrane IgD and the receptor for C3b (CR1) at the cell surface of murine B lymphocytes 73
Two conserved cysteine triads in human Ero1alpha cooperate for efficient disulfide bond formation in the endoplasmic reticulum 73
Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane 72
A novel secretory pathway with possible implications in antigen processing and presentation 71
Peroxides and Peroxidases in the Endoplasmic Reticulum: Integrating Redox Homeostasis and Oxidative Folding 71
Glutathione peroxidase 7 utilizes hydrogen peroxide generated by Ero1a to promote oxidative folding 70
Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway 70
Proteostasis and "redoxtasis" in the secretory pathway: Tales of tails from ERp44 and immunoglobulins. 70
Stress regulates aquaporin-8 permeability to impact cell growth and survival 68
Molecular bases of cyclic and specific disulfide interchange between human ERO1alpha protein and protein-disulfide isomerase (PDI). 67
Progressive waves of IL-1β release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways 67
The endoplasmic reticulum: a dynamic patchwork of specialized subregions 66
Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude 65
Protein quality control in the early secretory pathway 64
IRON CONTRIBUTES TO BORTEZOMIB SENSITIVITY IN MULTIPLE MYELOMA CELLS 63
Sialylation of N-Linked Glycans Influences the Immunomodulatory Effects of IgM on T Cells 62
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44 62
Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents 62
The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation 62
Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface 62
Cellular stress 61
The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19 61
Crystal structures of human Ero1α reveal the mechanisms of regulated and targeted oxidation of PDI 61
The endoplasmic reticulum 61
Expression of two immunoglobulin isotypes, IgM and IgA, with identical idiotype in the B cell lymphoma I.29 60
Expression of a receptor for sheep erythrocytes by B lymphocytes from a chronic lymphocytic leukemia patient. 60
Crystal structure of the ERp44-peroxiredoxin 4 complex reveals the molecular mechanisms of thiol-mediated protein retention 60
Tyrosine kinase signal modulation: a matter of H2O2 membrane permeability? 60
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion 60
Monitoring cytosolic H2O2 fluctuations arising from altered plasma membrane gradients or from mitochondrial activity 59
Increased TG lymphocytes in a case of Congenital Hypoplastic Anemia (Blackfan-Diamond Syndrome) 59
Stress as an intercellular signal: the emergence of stress associated molecular patterns (SAMP) 59
Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity 59
Synthesis and processing of the a heavy chains of secreted and membrane-bound IgA 58
Russell bodies: a general response of secretory cells to synthesis of a mutant immunoglobulin which can neither exit from, nor be degraded in, the endoplasmic reticulum 58
CD36 is a ditopic glycoprotein with the N-Terminal domain implicated in intracellular transport 58
Mitochondrial Aquaporin-8: A Functional Peroxiporin? Response to Marinelli and Marchissio 58
Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages 58
KIF3C, a novel member of the kinesin superfamily: sequence, expression, and mapping to human chromosome 2 at 2p23 57
PROGRESSIVELY IMPAIRED PROTEASOMAL CAPACITY DURING TERMINAL PLASMA CELL DIFFERENTIATION 57
Role of the early secretory pathway in SARS-CoV-2 infection 57
Chemo-metabolic regulation of immune responses by Tregs 56
B- to Plasma-Cell Terminal Differentiation Entails Oxidative Stress and Profound Reshaping of the Antioxidant Responses 56
Oxidative protein folding in the secretory pathway and redox-signaling across compartments and cells 55
COLTURE CELLULARI: TECNICHE DI BASE E APPLICAZIONI IN ONCOLOGIA 55
Stress, protein (mis)folding, and signaling: the redox connection 55
Different redox sensitivity of endoplasmic reticulum associated degradation clients suggests a novel role for disulphide bonds in secretory proteins 55
Quality control of ER synthetized proteins: an exposed thiol group as a three-way switch mediating assembly, retention and degradation 54
Dynamic regulation of Ero1α and Prx4 localization in the secretory pathway* 54
Role of SELENOF as a gatekeeper of secreted disulfide-rich glycoproteins 54
High rates of thioredoxin secretion correlate with growth arrest in hepatoma cells 53
Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. 53
Transfer of H2O2 from Mitochondria to the endoplasmic reticulum via Aquaporin-11 52
Quality control in the endoplasmic reticulum protein factory 52
Manipulation of Oxidative Protein Folding and PDI Redox State in Mammalian Cells 52
Dysregulated IL-1β Secretion in Autoinflammatory Diseases: A Matter of Stress? 52
Cysteines as Redox Molecular Switches and Targets of Disease. 52
Totale 7.513
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Categoria #
all - tutte 76.616
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 76.616
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202266 0 0 0 23 1 3 9 0 12 2 6 10
2022/2023937 380 228 57 16 5 119 19 59 27 7 2 18
2023/2024563 6 23 66 32 54 168 26 53 1 31 30 73
2024/20252.282 259 29 43 75 74 217 276 175 419 348 172 195
2025/20267.055 530 518 432 1.074 484 216 739 555 1.960 391 84 72
Totale 11.139