IRIS
SITIA, ROBERTO
 Distribuzione geografica
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Continente #
AS - Asia 2.898
NA - Nord America 1.853
EU - Europa 1.191
SA - Sud America 913
AF - Africa 56
OC - Oceania 7
Totale 6.918
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Nazione #
US - Stati Uniti d'America 1.780
SG - Singapore 1.285
BR - Brasile 790
CN - Cina 758
SE - Svezia 507
HK - Hong Kong 423
VN - Vietnam 206
IT - Italia 171
RU - Federazione Russa 167
DE - Germania 100
IN - India 63
FI - Finlandia 52
GB - Regno Unito 44
AR - Argentina 40
AT - Austria 35
CA - Canada 33
PL - Polonia 29
MX - Messico 26
IE - Irlanda 21
TR - Turchia 21
EC - Ecuador 18
ID - Indonesia 18
JP - Giappone 18
CO - Colombia 17
ZA - Sudafrica 17
BD - Bangladesh 16
IQ - Iraq 15
VE - Venezuela 15
PY - Paraguay 13
ES - Italia 12
NL - Olanda 12
UZ - Uzbekistan 12
MA - Marocco 10
FR - Francia 9
PK - Pakistan 9
AE - Emirati Arabi Uniti 8
PE - Perù 8
KE - Kenya 7
LT - Lituania 7
CL - Cile 6
KR - Corea 6
UA - Ucraina 6
AU - Australia 5
AZ - Azerbaigian 4
BE - Belgio 4
EG - Egitto 4
SA - Arabia Saudita 4
TN - Tunisia 4
BN - Brunei Darussalam 3
BO - Bolivia 3
CI - Costa d'Avorio 3
DO - Repubblica Dominicana 3
IL - Israele 3
MY - Malesia 3
SK - Slovacchia (Repubblica Slovacca) 3
UY - Uruguay 3
BB - Barbados 2
BG - Bulgaria 2
BH - Bahrain 2
DZ - Algeria 2
ET - Etiopia 2
IR - Iran 2
JM - Giamaica 2
JO - Giordania 2
KG - Kirghizistan 2
MK - Macedonia 2
NZ - Nuova Zelanda 2
OM - Oman 2
PH - Filippine 2
PS - Palestinian Territory 2
SN - Senegal 2
SV - El Salvador 2
TW - Taiwan 2
AL - Albania 1
AO - Angola 1
BA - Bosnia-Erzegovina 1
CM - Camerun 1
CR - Costa Rica 1
CZ - Repubblica Ceca 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
IS - Islanda 1
KW - Kuwait 1
KZ - Kazakistan 1
LB - Libano 1
LK - Sri Lanka 1
LU - Lussemburgo 1
MN - Mongolia 1
MU - Mauritius 1
NG - Nigeria 1
NO - Norvegia 1
PA - Panama 1
SI - Slovenia 1
SO - Somalia 1
SY - Repubblica araba siriana 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
Totale 6.918
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Città #
Singapore 490
Hong Kong 422
Dallas 285
Ashburn 271
Shanghai 203
Hefei 184
Lawrence 175
Princeton 175
New York 103
Beijing 86
Ho Chi Minh City 84
Milan 82
Los Angeles 67
São Paulo 66
Moscow 54
Hanoi 33
Helsinki 31
Washington 30
Boardman 28
Warsaw 28
Guangzhou 26
Pune 26
Santa Clara 26
Belo Horizonte 25
Rio de Janeiro 25
Munich 23
Nuremberg 21
The Dalles 21
Dublin 20
Stockholm 18
Montreal 17
Turku 17
Boston 16
Columbus 16
Orem 16
Tokyo 16
Vienna 15
Brooklyn 14
Campinas 14
Denver 14
Brasília 13
London 13
Poplar 13
Porto Alegre 13
Houston 12
Seattle 12
Atlanta 11
San Francisco 11
Ankara 10
Chicago 10
Council Bluffs 10
Johannesburg 10
Biên Hòa 9
Chennai 9
Hangzhou 9
Tashkent 9
Haiphong 8
Phoenix 8
Uberlândia 8
Betim 7
Curitiba 7
Da Nang 7
Goiânia 7
Mexico City 7
Mumbai 7
Quito 7
Ribeirão Preto 7
Salvador 7
Shenzhen 7
Sorocaba 7
Trento 7
Aracaju 6
Caracas 6
Contagem 6
Dhaka 6
Dubai 6
Halle 6
Hanover 6
Lima 6
Nairobi 6
Recife 6
Shijiazhuang 6
São Bernardo do Campo 6
Thái Bình 6
Tianjin 6
Amsterdam 5
Bauru 5
Buenos Aires 5
Falkenstein 5
Guarulhos 5
Juiz de Fora 5
Osasco 5
Suzano 5
Taboão da Serra 5
Americana 4
Baghdad 4
Baku 4
Belém 4
Calgary 4
Cambridge 4
Totale 3.718
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Nome #
CREB3L1 and CREB3L2 control Golgi remodelling during decidualization of endometrial stromal cells 104
A RIDDle solved: why an intact IRE1α/XBP-1 signaling relay is key for humoral immune responses 88
A dynamic study of protein secretion and aggregation in the secretory pathway 78
ANTIBODY SYNTHESIS AND ASSEMBLY 74
A pH-Regulated Quality Control Cycle for Surveillance of Secretory Protein Assembly 71
Profound architectural and functional readjustments of the secretory pathway in decidualization of endometrial stromal cells 71
Mechanisms of Oxidative Protein Folding and Thiol-Dependent Quality Control: Tales of Cysteines and Cystines, Tiziana Anelli and Roberto Sitia 69
Assessing Heterogeneity of Osteolytic Lesions in Multiple Myeloma by ¹H HR-MAS NMR Metabolomics. 68
Iron increases the susceptibility of multiple myeloma cells to bortezomib 66
A peptide extension dictates IgM polymerization 65
Inadequate BiP availability defines endoplasmic reticulum stress 64
A computer-driven approach to PCR-based differential screening, alternative to differential display 63
A virtuous cycle operated by ERp44 and ERGIC-53 guarantees proteostasis in the early secretory compartment 63
Progressive quality control of secretory proteins in the early secretory compartment by ERp44 62
Pivotal Advance: Protein synthesis modulates responsiveness of differentiating and malignant plasma cells to proteasome inhibitors 62
Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail 62
MHC Class II Transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity 62
Atypical IgM on T cells predict relapse and steroid dependence in idiopathic nephrotic syndrome 62
A New Fluorogenic Peptide Determines Proteasome Activity in Single Cells 62
Endoplasmic reticulum oxidoreductase 1 alpha modulates prostate cancer hallmarks 61
Ero1α Regulates Ca2+ Fluxes at the Endoplasmic Reticulum-Mitochondria Interface (MAM) 60
Biochemical nature of Russell Bodies. 60
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria 59
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells 58
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 58
Regulation of calcium fluxes by GPX8, a type-II transmembrane peroxidase enriched at the mitochondria-associated endoplasmic reticulum membrane 57
Plasma cells require autophagy for sustainable immunoglobulin production 56
ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family 56
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation 56
Two conserved cysteine triads in human Ero1alpha cooperate for efficient disulfide bond formation in the endoplasmic reticulum 54
Zinc regulates ERp44-dependent protein quality control in the early secretory pathway 54
Biogenesis of secretory immunoglobulin M requires intermediate non-native disulfide bonds and engagement of the protein disulfide isomerase ERp44 54
A novel pathway for secretory proteins? 53
A persulfidation-based mechanism controls aquaporin-8 conductance 53
Pathogenesis of ER Storage Disorders: Modulating Russell Body Biogenesis by Altering Proximal and Distal Quality Control 52
Aggresomes and Russell bodies. Symptoms of cellular indigestion? 52
A novel secretory pathway for interleukin 1ß, a protein lacking a signal sequence 52
Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway 52
Physiology and pathology of proteostasis in the early secretory compartment 52
The CXXCXXC motif determines the folding, structure and stability of human Ero1-Lalpha 51
Dampening Ab responses using proteasome inhibitors following in vivo B cell activation 51
Proteostasis and "redoxtasis" in the secretory pathway: Tales of tails from ERp44 and immunoglobulins. 51
Peroxides and Peroxidases in the Endoplasmic Reticulum: Integrating Redox Homeostasis and Oxidative Folding 49
Glutathione peroxidase 7 utilizes hydrogen peroxide generated by Ero1a to promote oxidative folding 49
Aberrant disulphide bonding contributes to the ER retention of alpha1-antitrypsin deficiency variants. 49
Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 48
Aspects of gene regulation during the unfolded protein response in human cells 47
The secretory capacity of a cell depends on the efficiency of endoplasmic reticulum-associated degradation 47
Stress as an intercellular signal: the emergence of stress associated molecular patterns (SAMP) 47
Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane 47
Author Correction: Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface 45
Cellular stress 45
Molecular bases of cyclic and specific disulfide interchange between human ERO1alpha protein and protein-disulfide isomerase (PDI). 45
Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface 45
The endoplasmic reticulum: a dynamic patchwork of specialized subregions 44
Sialylation of N-Linked Glycans Influences the Immunomodulatory Effects of IgM on T Cells 44
Redox crosstalk at endoplasmic reticulum (ER) membrane contact sites (MCS) uses toxic waste to deliver messages 44
Tyrosine kinase signal modulation: a matter of H2O2 membrane permeability? 43
Progressive waves of IL-1β release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways 43
Ratiometric sensing of BiP-client versus BiP levels by the unfolded protein response determines its signaling amplitude 43
The endoplasmic reticulum 43
A spatial association between membrane IgD and the receptor for C3b (CR1) at the cell surface of murine B lymphocytes 42
Crystal structure of the ERp44-peroxiredoxin 4 complex reveals the molecular mechanisms of thiol-mediated protein retention 42
A novel secretory pathway with possible implications in antigen processing and presentation 41
Stress regulates aquaporin-8 permeability to impact cell growth and survival 41
COLTURE CELLULARI: TECNICHE DI BASE E APPLICAZIONI IN ONCOLOGIA 41
Mitochondrial Aquaporin-8: A Functional Peroxiporin? Response to Marinelli and Marchissio 41
The Importance Of Naturally Attenuated Sars-Cov-2 In The Fight Against Covid-19 41
Protein quality control in the early secretory pathway 40
Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity 40
Chemo-metabolic regulation of immune responses by Tregs 39
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44 39
PROGRESSIVELY IMPAIRED PROTEASOMAL CAPACITY DURING TERMINAL PLASMA CELL DIFFERENTIATION 39
Secretion of immunoglobulin M assembly intermediates in the presence of reducing agents 39
Dysregulated IL-1β Secretion in Autoinflammatory Diseases: A Matter of Stress? 39
Stress, protein (mis)folding, and signaling: the redox connection 39
Role of SELENOF as a gatekeeper of secreted disulfide-rich glycoproteins 39
Crystal structures of human Ero1α reveal the mechanisms of regulated and targeted oxidation of PDI 39
Expression of a receptor for sheep erythrocytes by B lymphocytes from a chronic lymphocytic leukemia patient. 38
Synthesis and processing of the a heavy chains of secreted and membrane-bound IgA 37
Oxidative protein folding in the secretory pathway and redox-signaling across compartments and cells 37
Redox-Dependent Circuits Regulating B Lymphocyte Physiology 37
IRON CONTRIBUTES TO BORTEZOMIB SENSITIVITY IN MULTIPLE MYELOMA CELLS 36
Expression of two immunoglobulin isotypes, IgM and IgA, with identical idiotype in the B cell lymphoma I.29 36
Dynamic regulation of Ero1α and Prx4 localization in the secretory pathway* 36
Glycoprotein quality control in the endoplasmic reticulum: Mannose trimming by ER Mannosidase I times the proteasomal degradation of unassembled immunoglobulin subunits 36
Role of the early secretory pathway in SARS-CoV-2 infection 36
Different redox sensitivity of endoplasmic reticulum associated degradation clients suggests a novel role for disulphide bonds in secretory proteins 36
Manipulation of Oxidative Protein Folding and PDI Redox State in Mammalian Cells 35
Monitoring cytosolic H2O2 fluctuations arising from altered plasma membrane gradients or from mitochondrial activity 35
Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish. 35
Production of H2O2 in the Endoplasmic Reticulum Promotes In Vivo Disulfide Bond Formation 35
Increased TG lymphocytes in a case of Congenital Hypoplastic Anemia (Blackfan-Diamond Syndrome) 35
The unconventional secretion of IL-1b: handling a dangerous weapon to optimize inflammatory responses 35
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion 34
Reduction of inter-chain disulfide bonds precedes the dislocation of Ig-µ chains from the endoplasmic reticulum to the cytosol for proteasomal degradation 34
Proteostenosis and Plasma Cell Pathophysiology 34
B- to Plasma-Cell Terminal Differentiation Entails Oxidative Stress and Profound Reshaping of the Antioxidant Responses 33
Managing and exploiting stress in the antibody factory 33
Membrane-bound and secreted IgA contain structurally different a chains 33
Totale 4.902
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Categoria #
all - tutte 64.827
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 64.827
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20216 0 0 0 0 0 0 1 0 1 0 4 0
2021/202266 0 0 0 23 1 3 9 0 12 2 6 10
2022/2023937 380 228 57 16 5 119 19 59 27 7 2 18
2023/2024563 6 23 66 32 54 168 26 53 1 31 30 73
2024/20252.282 259 29 43 75 74 217 276 175 419 348 172 195
2025/20263.066 530 518 432 1.074 484 28 0 0 0 0 0 0
Totale 7.150