IRIS
CURNIS, FLAVIO
 Distribuzione geografica
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Continente #
AS - Asia 1.174
NA - Nord America 936
EU - Europa 923
SA - Sud America 349
Continente sconosciuto - Info sul continente non disponibili 46
AF - Africa 28
OC - Oceania 2
Totale 3.458
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Nazione #
US - Stati Uniti d'America 894
RU - Federazione Russa 550
SG - Singapore 432
CN - Cina 392
BR - Brasile 293
HK - Hong Kong 135
SE - Svezia 128
VN - Vietnam 99
IT - Italia 96
FR - Francia 56
BD - Bangladesh 31
DE - Germania 28
AR - Argentina 20
GB - Regno Unito 20
IN - India 20
CA - Canada 18
EC - Ecuador 13
FI - Finlandia 13
ID - Indonesia 13
IE - Irlanda 10
ZA - Sudafrica 10
AT - Austria 7
CO - Colombia 7
MX - Messico 7
PY - Paraguay 7
JP - Giappone 6
IQ - Iraq 5
MA - Marocco 5
MY - Malesia 5
NP - Nepal 5
UZ - Uzbekistan 5
AE - Emirati Arabi Uniti 4
PK - Pakistan 4
AZ - Azerbaigian 3
CL - Cile 3
CR - Costa Rica 3
NI - Nicaragua 3
NL - Olanda 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
VE - Venezuela 3
AL - Albania 2
AU - Australia 2
DZ - Algeria 2
ES - Italia 2
HN - Honduras 2
IR - Iran 2
JM - Giamaica 2
JO - Giordania 2
KR - Corea 2
LB - Libano 2
LT - Lituania 2
NG - Nigeria 2
PE - Perù 2
RO - Romania 2
TR - Turchia 2
UA - Ucraina 2
XK - ???statistics.table.value.countryCode.XK??? 2
AO - Angola 1
BB - Barbados 1
BE - Belgio 1
BM - Bermuda 1
BO - Bolivia 1
BW - Botswana 1
DM - Dominica 1
DO - Repubblica Dominicana 1
ET - Etiopia 1
GA - Gabon 1
GE - Georgia 1
KE - Kenya 1
KG - Kirghizistan 1
PT - Portogallo 1
SA - Arabia Saudita 1
SC - Seychelles 1
TH - Thailandia 1
TW - Taiwan 1
Totale 3.414
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Città #
Singapore 157
Ashburn 137
Moscow 136
Hong Kong 131
San Jose 118
Dallas 85
Council Bluffs 59
Hefei 59
Lawrence 59
Princeton 59
Shanghai 58
Lauterbourg 50
Milan 48
Ho Chi Minh City 34
Beijing 30
São Paulo 29
Hanoi 25
New York 20
Phoenix 16
Santa Clara 16
Rio de Janeiro 14
Nuremberg 13
Dublin 11
Helsinki 11
The Dalles 10
Los Angeles 9
Hangzhou 8
Miano 8
Columbus 7
Pune 7
Verona 7
Da Nang 6
Philadelphia 6
Brasília 5
Chicago 5
Curitiba 5
Dhaka 5
Haiphong 5
Jakarta 5
Seattle 5
Tokyo 5
Belo Horizonte 4
Biên Hòa 4
Boston 4
Criciúma 4
Goiânia 4
Guangzhou 4
Guayaquil 4
Hải Dương 4
Johannesburg 4
Manchester 4
Mexico City 4
Quito 4
Salvador 4
São Bernardo do Campo 4
Toronto 4
Atlanta 3
Baku 3
Boardman 3
Brooklyn 3
Campinas 3
Cape Town 3
Chennai 3
Cleveland 3
Dubai 3
Franca 3
Houston 3
Kathmandu 3
Managua 3
Porto Alegre 3
Santa Rita 3
Santiago 3
Staten Island 3
Tashkent 3
Amman 2
Appleton 2
Araguaína 2
Belém 2
Berlin 2
Borås 2
Buffalo 2
Bình Tân 2
Campina Grande 2
Can Tho 2
Canoas 2
Caratinga 2
Chapecó 2
Charleston 2
Chengdu 2
Cotia 2
Deer Park 2
Diamantina 2
Duhok 2
Duque de Caxias 2
Etobicoke 2
Fort Lauderdale 2
Fortaleza 2
Guarulhos 2
Ha Long 2
Hamilton 2
Totale 1.649
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Nome #
Tumor pretargeting with avidin improves the therapeutic index of biotinylated tumor necrosis factor alpha in mouse models 100
R-CHOP preceded by blood-brain barrier permeabilization with engineered tumor necrosis factor-α in primary CNS lymphoma 96
A stapled chromogranin A-derived peptide is a potent dual ligand for integrins αvβ6 and αvβ8 95
A new chromogranin A-dependent angiogenic switch activated by thrombin 86
Spatiotemporal regulation of tumor angiogenesis by circulating chromogranin a cleavage and neuropilin-1 engagement 79
Tumor targeting with biotinylated tumor necrosis factor alpha: Structure-activity relationships and mechanism of action on avidin pretargeted tumor cells 75
Isoaspartate-glycine-arginine: A new tumor vasculature-targeting motif 73
Enhancement of tumor necrosis factor a antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13) 73
Succinimide-Based Conjugates Improve IsoDGR Cyclopeptide Affinity to αvβ3 without Promoting Integrin Allosteric Activation 73
T cells redirected to a minor histocompatibility antigen instruct intratumoral TNFα expression and empower adoptive cell therapy for solid tumors 71
Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells 68
Roles of tumor necrosis factor p55 and p75 receptors in TNF-alpha-induced vascular permeability 67
Chromogranin A Restricts Drug Penetration and Limits the Ability of NGR-TNF to Enhance Chemotherapeutic Efficacy 67
Chromogranin A is preferentially cleaved into pro-angiogenic peptides in the bone marrow of multiple myeloma patients 67
STRUCTURAL BASIS FOR THE INTERATION OF ISODGR WITH RGD-BINDING SITE OF αvβ3 INTEGRIN 66
Regulation of tumor growth by circulating full-length chromogranin A 63
Oxidation-induced structural changes of ceruloplasmin foster NGR-motifs deamidation that promote integrin binding and signaling 63
Structure-activity relationships of chromogranin A in cell adhesion - Identification of an adhesion site for fibroblasts and smooth muscle cells 61
NGR-Tagged Nano-Gold: a new CD13-selective carrier for cytokine delivery to tumors 61
Targeting TNF-alpha to Neoangiogenic Vessels Enhances Lymphocyte Infiltration in Tumors and Increases the Therapeutic Potential of Immunotherapy 61
Synergistic damage of tumor vessels with ultra low-dose endothelial-monocyte activating polypeptide-II and neovasculature-targeted tumor necrosis factor-alpha 61
Critical Role of Flanking Residues in NGR-to-isoDGR Transition and CD13/Integrin Receptor Switching 60
Chromogranin A protects vessels against tumor necrosis factor alpha-induced vascular leakage 60
Chromogranin A expression in neoplastic cells affects tumor growth and morphogenesis in mouse models 59
Structure-activity relationships of linear and cyclic peptides containing the NGR tumor-homing motif 59
Targeted drug delivery and penetration into solid tumors. 58
Targeted delivery of IFN gamma to tumor vessels uncouples antitumor from counterregulatory mechanisms 58
Isoaspartate-dependent molecular switches for integrin-ligand recognition 57
Boosting Interleukin-12 Antitumor Activity and Synergism with Immunotherapy by Targeted Delivery with isoDGR-Tagged Nanogold 55
Role of vasostatin-1 C-terminal region in fibroblast cell adhesion 54
The neovasculature homing motif NGR: more than meets the eye 53
Cleavage of chromogranin A N-terminal domain by plasmin provides a new mechanism for regulating cell adhesion 53
Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function 52
Synergistic antitumor activity of cisplatin, paclitaxel, and gemcitabine with tumor vasculature-targeted tumor necrosis factor-alpha 52
Enhancement of Tumor Homing by Chemotherapy-Loaded Nanoparticles 52
Crucial role for interferon gamma in the synergism between tumor vasculature-targeted tumor necrosis factor alpha (NGR-TNF) and doxorubicin 51
Peptide-mediated Targeting of Cytokines to Tumor Vasculature: the NGR-hTNF Example 51
Biochemical characterization and crystal structure of a recombinant hen avidin and its acidic mutant expressed in Escherichia coli 51
Coupling tumor necrosis factor-alpha with alpha(v) integrin ligands improves its antineoplastic activity 51
IsoDGR-tagged Albumin: a New αvβ3 Selective Carrier for Nanodrug Delivery to Tumors 50
Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration 50
Spontaneous formation of L-isoaspartate and gain of function in fibronectin 50
Novel phage display-derived neuroblastoma-targeting peptides potentiate the effect of drug nanocarriers in preclinical settings 49
Combined targeting of perivascular and endothelial tumor cells enhances anti-tumor efficacy of liposomal chemotherapy in neuroblastoma 49
Chromogranin A binds to alphavbeta6-integrin and promotes wound healing in mice. 48
Immunogenic and structural properties of the Asn-Gly-Arg (NGR) tumor neovasculature-homing motif 48
Targeting tumor vasculature with TNF leads effector t cells to the tumor and enhances therapeutic efficacy of immune checkpoint blockers in combination with adoptive cell therapy 48
The Importance of Detail: How Differences in Ligand Structures Determine Distinct Functional Responses in Integrin α v β 3 48
Caspase inhibition reveals functional cooperation between p55-and p75-TNF receptors in cell necrosis 47
Overcoming Biological Barriers in Neuroblastoma Therapy: The Vascular Targeting Approach with Liposomal Drug Nanocarriers 47
Critical role of indoleamine 2,3-dioxygenase in tumor resistance to repeated treatments with targeted IFN gamma 46
Production and structure characterisation of recombinant chromogranin A N-terminal fragments (vasostatins) - Evidence of dimer-monomer equilibria 46
Glycine N-Methylation in NGR-Tagged Nanocarriers Prevents Isoaspartate Formation and Integrin Binding without Impairing CD13 Recognition and Tumor Homing 46
Neuroblastoma-targeted nanocarriers improve drug delivery and penetration, delay tumor growth and abrogate metastatic diffusion 45
Tumor Vasculature Targeting Through NGR Peptide-Based Drug Delivery Systems 43
Regulation of endothelial cell shape and barrier function by chromogranin A 43
Ceruloplasmin functional changes in Parkinson’s disease-cerebrospinal fluid 42
Selective imaging of the angiogenic relevant integrins αvβ3 and α5β1 42
Biotinylation sites of tumor necrosis factor-alpha determined by liquid chromatography-mass spectrometry 39
Peptides for Inhibiting Tumor Growth 1
Production and characterization of recombinant human and murine TNF 1
CERULOPLASMIN OXIDATION, A FEATURE OF PARKINSON'S AND ALZHEIMER'S DISEASES CSF, INHIBITS FERROXIDASE ACTIVITY AND PROMOTES CELLULAR IRON RETENTION 1
Novel tumor-homing peptides, conjugation products thereof and their use in diagnostic and therapy 1
The molecular microenvironment critically affects the formation of isoDGR-dependent integrin binding sites in fibronectin 1
Antitumor activity and mechanism of action of ultra-low dose endothelial-monocyte activating polypeptide-II combined with a tumor targeting derivative of TNF 1
Tumor-penetrating peptide-coated nanoparticles as a novel strategy for the targeted therapy of neuroblastoma 1
R-CHOP PRECEDED BY BLOOD-BRAIN BARRIER PERMEABILIZATION WITH ENGINEERED TUMOR NECROSIS FACTOR (TNF) IN RELAPSED OR REFRACTORY PRIMARY DIFFUSE LARGE B-CELL LYMPHOMA OF THE CNS (RPCNSL): FINAL RESULTS OF THE INGRID TRIAL 1
Chromogranin A-derived vasostatin-1 contains a sequence homologous to ezrin-radixin-moesin binding phosphoprotein 50 (EBP50) that regulates cell adhesion 1
Chromogranin A-derived peptides and uses thereof 1
NGR CONJUGATES AND USES THEREOF 1
Characterization and anti-tumor functionality of a neuroblastoma-specific peptide, either free or conjugated to nanocarriers 1
Enhancement of tumor penetration by drug-loaded nanoparticles: An innovative targeted strategy for neuroblastoma 1
NGR-TNF, a Selective Vessel-Targeting Agent, Increases the Therapeutic Potential of Chemo-Immunotherapy 1
Myocardial production and secretion of chromogranin A in hyperthrophic cardiomyopathy 1
Myocardial production of Chromogranin A: a new regulatory peptide of myocyte function 1
New approaches to improve the therapeutic index of Tumor Necrosis Factor α (TNF). 1
Structural basis for L-isoDGIR stereospecific recognition of alpha v beta 3 1
Effect of systemic administration of chromogranin A on tumor metastatization in animal models 1
A critical assessment of force field accuracy against NMR data for cyclic peptides containing beta-amino acids 1
Totale 3.458
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Categoria #
all - tutte 26.182
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.182
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202218 0 0 0 10 0 3 1 1 0 0 0 3
2022/2023268 134 33 28 1 0 34 9 13 11 0 2 3
2023/202450 0 0 4 4 1 10 4 6 0 2 6 13
2024/2025677 97 6 7 15 11 55 113 51 144 93 46 39
2025/20261.925 132 188 146 321 107 26 180 137 497 84 31 76
2026/2027494 57 123 121 193 0 0 0 0 0 0 0 0
Totale 3.458