IRIS
GRITTI, ANGELA
 Distribuzione geografica
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Continente #
AS - Asia 2.061
NA - Nord America 1.033
EU - Europa 672
SA - Sud America 393
AF - Africa 25
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 4.187
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Nazione #
SG - Singapore 967
US - Stati Uniti d'America 963
CN - Cina 646
BR - Brasile 345
HK - Hong Kong 278
DE - Germania 146
IT - Italia 123
RU - Federazione Russa 99
GB - Regno Unito 65
VN - Vietnam 58
FI - Finlandia 57
CA - Canada 44
SE - Svezia 41
JP - Giappone 27
FR - Francia 24
NL - Olanda 24
MX - Messico 21
PL - Polonia 19
LT - Lituania 17
AR - Argentina 16
IN - India 16
BD - Bangladesh 15
ES - Italia 15
AT - Austria 14
ZA - Sudafrica 14
EC - Ecuador 11
TR - Turchia 9
CO - Colombia 8
IQ - Iraq 8
UZ - Uzbekistan 8
IE - Irlanda 6
PK - Pakistan 6
PT - Portogallo 6
UA - Ucraina 6
ID - Indonesia 5
VE - Venezuela 5
BE - Belgio 4
CZ - Repubblica Ceca 3
EG - Egitto 3
JO - Giordania 3
KE - Kenya 3
OM - Oman 3
UY - Uruguay 3
AU - Australia 2
AZ - Azerbaigian 2
BH - Bahrain 2
CH - Svizzera 2
IL - Israele 2
MA - Marocco 2
NP - Nepal 2
PE - Perù 2
PY - Paraguay 2
SA - Arabia Saudita 2
AE - Emirati Arabi Uniti 1
CL - Cile 1
DM - Dominica 1
DO - Repubblica Dominicana 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
HN - Honduras 1
IR - Iran 1
JM - Giamaica 1
SI - Slovenia 1
TT - Trinidad e Tobago 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 4.187
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Città #
Singapore 456
Hong Kong 278
Dallas 185
Ashburn 156
Beijing 139
Shanghai 130
Hefei 121
Munich 46
Los Angeles 40
São Paulo 40
New York 37
Boardman 31
Frankfurt am Main 30
Helsinki 28
Milan 28
Moscow 26
Turku 26
Ho Chi Minh City 24
Nuremberg 23
Pisa 22
Tokyo 21
San Francisco 17
Warsaw 17
Denver 16
Montreal 16
Orem 15
Belo Horizonte 14
Falkenstein 14
London 14
Poplar 14
Guangzhou 13
Houston 13
Lawrence 13
Princeton 13
Santa Clara 13
Atlanta 12
Manchester 12
Charlotte 11
Johannesburg 11
Phoenix 11
Boston 10
Hanoi 10
Mexico City 10
Toronto 10
Brooklyn 9
Amsterdam 8
Naples 8
Secaucus 8
Washington 8
Chicago 7
Jiaxing 7
Ribeirão Preto 7
Tashkent 7
Brasília 6
Cambridge 6
Chennai 6
Dublin 6
Ottawa 6
Rio de Janeiro 6
Seattle 6
Vienna 6
Ankara 5
Curitiba 5
Fortaleza 5
North Bergen 5
Quito 5
Shenzhen 5
Stockholm 5
Bologna 4
Brussels 4
Cesano Boscone 4
Fuzhou 4
Goiânia 4
Guarulhos 4
Hangzhou 4
Lannion 4
Mumbai 4
Pelotas 4
Shelburne 4
São Gonçalo 4
Tianjin 4
Turin 4
Amman 3
Aveiro 3
Baghdad 3
Bagnolo San Vito 3
Berlin 3
Biên Hòa 3
Buffalo 3
Columbus 3
Franca 3
Lappeenranta 3
Marília 3
Milwaukee 3
Monza 3
Ninh Bình 3
Omsk 3
Pittsburgh 3
Potomac 3
Recife 3
Totale 2.448
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Nome #
In vivo Gene Therapy to the Liver and Nervous System: Promises and Challenges 94
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 74
Investigating the Role of Vector DNA Sensing and Transgene Expression on Innate Immune Signaling and Cell Toxicity upon AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 70
AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain 69
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 69
Human iPSC-derived neural stem cells display a radial glia-like signaturein vitroand favorable long-term safety in transplanted mice 67
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System 66
Exploring the identity and safety of hiPSC-derived neural stem/progenitor cells: implications for cell therapy approaches 66
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy 64
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 62
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 61
Development of editing technologies for allele-specific silencing or precise correction of mutation hotspots affecting Alexander disease's patients 61
Isolation and Culture of Neural Stem/Progenitor Cells from the Postnatal Periventricular Region 59
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS model 57
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 56
Genome-wide analyses of regulatory regions and transcripts in hiPSC-derived neural stem/progenitor cells to define their safety and efficacy in cell therapy approaches for neurological disorders 56
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 56
Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases 55
Effect of hyperthermia on rhodamine 123 cytotoxicity in doxorubicin-sensitive and doxorubicin-resistant human breast carcinoma cell lines in vitro 53
Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy 52
A Human IPSC-Based Model of Globoid Cell Leukodystrophy Uncovers Early Neurodevelopmental Defects 52
Adult neural stem cells 51
Dissecting the Transcriptional and Epigenetic Landscape of hiPSC-Derived Neural Stem and Progenitor Cells: Implications for Cell Therapy Approaches 51
Clonal analyses and cryopreservation of neural stem cell cultures 50
Generation of neuronal/glial mixed cultures from human induced pluripotent stem cells (hiPSCs) 50
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy 50
Site-specific integration and tailoring of cassette design for sustainable gene transfer 49
Intracerebroventricular transplantation of human iPSC-derived neural stem cells (hiPSC-NSCs) into neonatal mice 48
Chimeric Lysosomal Enzymes with Improved Bioavailability to Advance Gene Therapy Strategies for Globoid Cell Leukodystrophy 46
Investigating the Role of Innate Immune Signaling in AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 46
Developing Allele-Specific Gene Editing Technologies for Silencing or Precise Correction of GFAP Mutations Causing Alexander's Disease 46
A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: Implication for metachromatic leukodystrophy diagnosis 46
Complete enzymatic correction of CNS tissue following intracerebral LV-mediated gene therapy in a murine model of GLD 45
Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS 45
Adult neurogenesis in serotonin transporter deficient mice 44
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 44
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes 43
In vitro Validation of Chimeric β-Galactosylceramidase Enzymes With Improved Enzymatic Activity and Increased Secretion 43
Clonal analyses and cryopreservation of neural stem cell cultures 43
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy 43
Human iPSC-derived neural stem cells displaying radial glia signature exhibit long-term safety in mice 42
Development of cutting-edge editing technologies to treat Alexander disease 42
Lentiviral Vector Gene Transfer is limited by the proteasome at post-entry steps in various Types of Stem Cells 42
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 41
Composition and organization of the SCZ: A large germinal layer containing neural stem Cells in the adult mammalian brain 41
Adult neural stem cells: Plasticity and developmental potential 39
Adult murine CNS stem cells express aquaporin channels 38
Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene 37
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS models 36
Neural stem cells: An overview 36
Optimized bicistronic lentiviral vectors to correct b-hexosaminidase deficiency in neural and hematopoietic stem/progenitor cells and progeny 35
Production of IL-10 in demyelinating inflammatory processes in the central nervous system [Cellule produttrici di IL-10 nei processi infiammatori demielinizzanti nel sistema nervoso centrale] 35
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis 35
Neuronal and glial cells derived from a murine model of GM2-gangliosidosis display typical hallmarks of pathology and represent a valuable model to test gene therapy strategies 34
Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: Relevance for in vivo cell tracking 34
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells 33
Patient-specific gene-corrected iPSC-derived neural stem/progenitor cells for autologous cell therapy applications in lysosomal storage diseases 33
Therapeutic potential of genetically modified neural stem cells (NSCs) in a mouse model of Globoid Cell Leukodystrophy (GLD) 32
Direct Intra-Brain LV-Mediated Gene Delivery Leads to Widespread Transgene Distribution and High-Level Enzymatic Correction in the Whole CNS of Twitcher Mice 32
Novel bicistronic lentiviral vectors correct β-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis 32
Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche. 32
Human brain endothelial cells and astrocytes produce IL-1β but not IL-10 30
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models 30
Patient-specific induced pluripotent stem cells (iPSCs) to model metachromatic leukodystrophy 29
Integrated computational analysis highlights unique miRNA signatures in the subventricular zone and striatum of GM2 gangliosidosis animal models 29
Differential effects of CGRP on adenylyl cyclase in adult and embryonic rat brain 29
Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195 29
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy 29
Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation 28
Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor 28
Neural Stem Cell Gene Therapy Ameliorates Pathology and Function in a Mouse Model of Globoid Cell Leukodystrophy 28
The neural stem cells and their transdifferentiation capacity 28
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents 27
Gene delivery targeted to oligodendrocytes using a lentiviral vector 27
Skeletal myogenic potential of human and mouse neural stem cells 26
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential 26
Perspective on innovative therapies for globoid cell leukodystrophy 26
Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells 26
Exploiting targeted epigenetic editing to increase the yield, homogeneity and purity of human iPSCderived oligodendrocyte cell populations 26
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system 25
Genome-wide definition of regulatory regions and transcripts during the transition from pluripotent to neural restricted stem cells 25
Early sulfatide storage and progressive neuronal and glial cell dysfunction revealed by human iPSC-based models of metachromatic leukodystrophy are rescued by lentiviral-mediated restoration of ARSA activity 25
Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells 25
Specific determination of β-galactocerebrosidase activity via competitive inhibition of β-galactosidase 24
Soluble or bound laminin elicit in human neuroblastoma cells short- or long-term potentiation of a K+ inwardly rectifying current: Relevance to neuritogenesis 24
Plasma membrane-associated glycohydrolases along differentiation of murine neural stem cells 24
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma 24
Region- and age-dependent alterations of glial-neuronal metabolic interactions correlate with CNS pathology in a mouse model of globoid cell leukodystrophy 24
Genome-Wide Definition of Regulatory Regions and Transcripts During the Transition from Pluripotent to Neural-Restricted Stem Cells 24
The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-natal CNS development 24
Neural stem cells: Plasticity and their transdifferentiation potential 24
Therapeutic advantages of combined gene/cell therapy strategies in a murine model of {GM}2 gangliosidosis 24
GENERATION OF SENSORY NEURONS AND SCHWANN CELLS FROM HUMAN-IPS CELLS OF CMT PATIENTS: A SUITABLE TOOL TO TEST NEW DEVELOPING DRUGS 24
Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury 24
Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology 24
Unique expression and localization of aquaporin- 4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny 24
Modelling globoid cell leukodystrophy using integration-free human induced pluripotent stem cells (hiPSC) 23
Gene therapy for lysosomal storage disorders 23
NEURAL PRECURSOR CELL CULTURES FROM GM2-GANGLIOSIDOSIS MURINE MODELS RECAPITULATE THE BIOCHEMICAL HALLMARKS OF THE BRAIN PATHOLOGY 22
Excitable properties in astrocytes derived from human embryonic CNS stem cells 22
Totale 3.966
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Categoria #
all - tutte 26.414
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.414
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20224 0 0 0 4 0 0 0 0 0 0 0 0
2022/202393 30 12 3 0 0 18 8 7 2 4 9 0
2023/2024373 1 1 10 16 12 7 6 11 0 5 247 57
2024/20251.727 165 8 26 98 82 135 295 192 307 113 145 161
2025/20262.164 475 337 237 634 455 26 0 0 0 0 0 0
Totale 4.366