IRIS
GRITTI, ANGELA
 Distribuzione geografica
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Continente #
AS - Asia 2.564
EU - Europa 2.446
NA - Nord America 2.384
SA - Sud America 418
Continente sconosciuto - Info sul continente non disponibili 186
AF - Africa 40
OC - Oceania 2
Totale 8.040
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Nazione #
US - Stati Uniti d'America 2.256
RU - Federazione Russa 1.612
SG - Singapore 1.022
CN - Cina 848
BR - Brasile 357
HK - Hong Kong 300
IT - Italia 210
VN - Vietnam 196
DE - Germania 154
FR - Francia 135
GB - Regno Unito 86
CA - Canada 69
FI - Finlandia 57
SE - Svezia 43
IN - India 38
JP - Giappone 34
NL - Olanda 33
BD - Bangladesh 30
MX - Messico 30
AR - Argentina 22
ES - Italia 21
ZA - Sudafrica 20
PL - Polonia 19
LT - Lituania 17
IQ - Iraq 16
AT - Austria 15
TR - Turchia 13
CO - Colombia 11
EC - Ecuador 11
UZ - Uzbekistan 11
ID - Indonesia 8
IE - Irlanda 8
UA - Ucraina 8
KE - Kenya 7
MY - Malesia 7
PK - Pakistan 7
PT - Portogallo 7
JM - Giamaica 6
VE - Venezuela 6
GR - Grecia 5
BE - Belgio 4
CR - Costa Rica 4
HN - Honduras 4
IL - Israele 4
JO - Giordania 4
PH - Filippine 4
SA - Arabia Saudita 4
TT - Trinidad e Tobago 4
AZ - Azerbaigian 3
CH - Svizzera 3
CL - Cile 3
CZ - Repubblica Ceca 3
EG - Egitto 3
ET - Etiopia 3
OM - Oman 3
PE - Perù 3
QA - Qatar 3
UY - Uruguay 3
AL - Albania 2
AU - Australia 2
BH - Bahrain 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
LC - Santa Lucia 2
MA - Marocco 2
NP - Nepal 2
PY - Paraguay 2
SV - El Salvador 2
AE - Emirati Arabi Uniti 1
BY - Bielorussia 1
BZ - Belize 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DM - Dominica 1
GA - Gabon 1
GT - Guatemala 1
HU - Ungheria 1
IR - Iran 1
KG - Kirghizistan 1
MM - Myanmar 1
NI - Nicaragua 1
PR - Porto Rico 1
PS - Palestinian Territory 1
SI - Slovenia 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.855
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Città #
Singapore 487
San Jose 415
Ashburn 330
Moscow 315
Hong Kong 295
Dallas 191
Beijing 149
Shanghai 131
Council Bluffs 124
Hefei 121
Lauterbourg 104
Phoenix 71
Ho Chi Minh City 65
Milan 56
Los Angeles 54
New York 52
Munich 46
Hanoi 44
São Paulo 40
Santa Clara 38
Orem 35
Frankfurt am Main 34
Boardman 31
Helsinki 28
Turku 26
Atlanta 25
Montreal 24
Nuremberg 24
Pisa 22
Tokyo 22
Denver 19
Manchester 19
Houston 18
San Francisco 18
Warsaw 17
Guangzhou 16
London 16
Mexico City 16
Boston 15
Johannesburg 15
Poplar 15
Amsterdam 14
Belo Horizonte 14
Chicago 14
Falkenstein 14
Princeton 14
Brooklyn 13
Chennai 13
Lawrence 13
Rome 12
Seattle 12
Charlotte 11
Da Nang 11
Toronto 11
Washington 11
Miami 10
Naples 9
Tashkent 9
Dublin 8
Secaucus 8
Turin 8
Jiaxing 7
Mumbai 7
Ribeirão Preto 7
Ankara 6
Baghdad 6
Brasília 6
Cambridge 6
Curitiba 6
Fortaleza 6
Nairobi 6
Ottawa 6
Rio de Janeiro 6
Shenzhen 6
Stockholm 6
Vienna 6
Biên Hòa 5
Bologna 5
Buffalo 5
Bến Tre 5
Cleveland 5
Dhaka 5
Hải Dương 5
Milwaukee 5
North Bergen 5
Paris 5
Queens 5
Quito 5
Tianjin 5
Yachiyo 5
Amman 4
Athens 4
Brussels 4
Cesano Boscone 4
Fuzhou 4
Goiânia 4
Guarulhos 4
Haiphong 4
Hangzhou 4
Lannion 4
Totale 4.015
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Nome #
AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain 157
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 151
In vivo Gene Therapy to the Liver and Nervous System: Promises and Challenges 140
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 130
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System 115
Exploring the identity and safety of hiPSC-derived neural stem/progenitor cells: implications for cell therapy approaches 113
Investigating the Role of Vector DNA Sensing and Transgene Expression on Innate Immune Signaling and Cell Toxicity upon AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 109
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy 109
Effect of hyperthermia on rhodamine 123 cytotoxicity in doxorubicin-sensitive and doxorubicin-resistant human breast carcinoma cell lines in vitro 108
Human iPSC-derived neural stem cells display a radial glia-like signaturein vitroand favorable long-term safety in transplanted mice 105
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 104
A Human IPSC-Based Model of Globoid Cell Leukodystrophy Uncovers Early Neurodevelopmental Defects 104
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 99
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 98
Generation of neuronal/glial mixed cultures from human induced pluripotent stem cells (hiPSCs) 97
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS model 96
Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy 95
Genome-wide analyses of regulatory regions and transcripts in hiPSC-derived neural stem/progenitor cells to define their safety and efficacy in cell therapy approaches for neurological disorders 94
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 93
Clonal analyses and cryopreservation of neural stem cell cultures 92
Adult neural stem cells 91
Development of editing technologies for allele-specific silencing or precise correction of mutation hotspots affecting Alexander disease's patients 90
Dissecting the Transcriptional and Epigenetic Landscape of hiPSC-Derived Neural Stem and Progenitor Cells: Implications for Cell Therapy Approaches 89
Isolation and Culture of Neural Stem/Progenitor Cells from the Postnatal Periventricular Region 89
Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases 88
Chimeric Lysosomal Enzymes with Improved Bioavailability to Advance Gene Therapy Strategies for Globoid Cell Leukodystrophy 88
Intracerebroventricular transplantation of human iPSC-derived neural stem cells (hiPSC-NSCs) into neonatal mice 87
Developing Allele-Specific Gene Editing Technologies for Silencing or Precise Correction of GFAP Mutations Causing Alexander's Disease 86
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy 85
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 83
Human iPSC-derived neural stem cells displaying radial glia signature exhibit long-term safety in mice 83
Adult neurogenesis in serotonin transporter deficient mice 83
Investigating the Role of Innate Immune Signaling in AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 82
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes 79
Development of cutting-edge editing technologies to treat Alexander disease 79
A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: Implication for metachromatic leukodystrophy diagnosis 79
Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS 78
Clonal analyses and cryopreservation of neural stem cell cultures 78
Complete enzymatic correction of CNS tissue following intracerebral LV-mediated gene therapy in a murine model of GLD 77
Adult neural stem cells: Plasticity and developmental potential 76
Site-specific integration and tailoring of cassette design for sustainable gene transfer 75
Adult murine CNS stem cells express aquaporin channels 74
Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: Relevance for in vivo cell tracking 73
Composition and organization of the SCZ: A large germinal layer containing neural stem Cells in the adult mammalian brain 73
Novel bicistronic lentiviral vectors correct β-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis 71
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy 71
Production of IL-10 in demyelinating inflammatory processes in the central nervous system [Cellule produttrici di IL-10 nei processi infiammatori demielinizzanti nel sistema nervoso centrale] 70
In vitro Validation of Chimeric β-Galactosylceramidase Enzymes With Improved Enzymatic Activity and Increased Secretion 70
Lentiviral Vector Gene Transfer is limited by the proteasome at post-entry steps in various Types of Stem Cells 69
Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene 68
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS models 66
Chimeric enzymes enhance treatment potential for globoid cell leukodystrophy through hematopoietic stem cell gene therapy 66
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 66
Neural stem cells: An overview 65
Optimized bicistronic lentiviral vectors to correct b-hexosaminidase deficiency in neural and hematopoietic stem/progenitor cells and progeny 62
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells 62
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis 61
Integrated computational analysis highlights unique miRNA signatures in the subventricular zone and striatum of GM2 gangliosidosis animal models 59
Human brain endothelial cells and astrocytes produce IL-1β but not IL-10 58
Direct Intra-Brain LV-Mediated Gene Delivery Leads to Widespread Transgene Distribution and High-Level Enzymatic Correction in the Whole CNS of Twitcher Mice 58
Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195 58
Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche. 58
Soluble or bound laminin elicit in human neuroblastoma cells short- or long-term potentiation of a K+ inwardly rectifying current: Relevance to neuritogenesis 57
Neuronal and glial cells derived from a murine model of GM2-gangliosidosis display typical hallmarks of pathology and represent a valuable model to test gene therapy strategies 57
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system 56
Therapeutic potential of genetically modified neural stem cells (NSCs) in a mouse model of Globoid Cell Leukodystrophy (GLD) 55
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential 55
Patient-specific gene-corrected iPSC-derived neural stem/progenitor cells for autologous cell therapy applications in lysosomal storage diseases 55
Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor 55
Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells 55
Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation 53
Skeletal myogenic potential of human and mouse neural stem cells 53
Neural Stem Cell Gene Therapy Ameliorates Pathology and Function in a Mouse Model of Globoid Cell Leukodystrophy 53
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma 51
Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells 51
Gene therapy for lysosomal storage disorders 51
The neural stem cells and their transdifferentiation capacity 51
Perspective on innovative therapies for globoid cell leukodystrophy 50
Neural stem cells: Plasticity and their transdifferentiation potential 50
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy 50
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models 50
Exploiting targeted epigenetic editing to increase the yield, homogeneity and purity of human iPSCderived oligodendrocyte cell populations 50
Patient-specific induced pluripotent stem cells (iPSCs) to model metachromatic leukodystrophy 49
Genome-wide definition of regulatory regions and transcripts during the transition from pluripotent to neural restricted stem cells 49
Early sulfatide storage and progressive neuronal and glial cell dysfunction revealed by human iPSC-based models of metachromatic leukodystrophy are rescued by lentiviral-mediated restoration of ARSA activity 48
Differential effects of CGRP on adenylyl cyclase in adult and embryonic rat brain 48
Gene delivery targeted to oligodendrocytes using a lentiviral vector 48
Modelling globoid cell leukodystrophy using integration-free human induced pluripotent stem cells (hiPSC) 47
Plasma membrane-associated glycohydrolases along differentiation of murine neural stem cells 47
Excitable properties in astrocytes derived from human embryonic CNS stem cells 47
Genome-Wide Definition of Regulatory Regions and Transcripts During the Transition from Pluripotent to Neural-Restricted Stem Cells 47
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents 47
The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-natal CNS development 46
Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology 46
EFFICIENT LENTIVIRAL GENE DELIVERY TO SCHWANN CELLS 45
Region- and age-dependent alterations of glial-neuronal metabolic interactions correlate with CNS pathology in a mouse model of globoid cell leukodystrophy 45
Therapeutic advantages of combined gene/cell therapy strategies in a murine model of {GM}2 gangliosidosis 45
GENERATION OF SENSORY NEURONS AND SCHWANN CELLS FROM HUMAN-IPS CELLS OF CMT PATIENTS: A SUITABLE TOOL TO TEST NEW DEVELOPING DRUGS 45
Inorganic mercury changes the fate of murine CNS stem cells 44
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors 44
Totale 7.227
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Categoria #
all - tutte 40.138
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 40.138
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20224 0 0 0 4 0 0 0 0 0 0 0 0
2022/202393 30 12 3 0 0 18 8 7 2 4 9 0
2023/2024373 1 1 10 16 12 7 6 11 0 5 247 57
2024/20251.727 165 8 26 98 82 135 295 192 307 113 145 161
2025/20265.088 475 337 237 634 455 149 583 397 1.372 283 92 74
2026/2027750 106 300 303 41 0 0 0 0 0 0 0 0
Totale 8.040