IRIS
GRITTI, ANGELA
 Distribuzione geografica
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Continente #
AS - Asia 281
EU - Europa 230
NA - Nord America 133
Totale 644
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Nazione #
SG - Singapore 144
CN - Cina 134
US - Stati Uniti d'America 132
RU - Federazione Russa 80
IT - Italia 53
SE - Svezia 36
DE - Germania 27
FI - Finlandia 16
GB - Regno Unito 4
IE - Irlanda 4
FR - Francia 3
JP - Giappone 3
NL - Olanda 3
ES - Italia 2
CA - Canada 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
Totale 644
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Città #
Singapore 96
Shanghai 32
Boardman 31
Moscow 23
Pisa 20
Ashburn 19
Frankfurt am Main 17
Helsinki 16
Milan 16
Lawrence 13
Princeton 13
Guangzhou 10
Beijing 8
Los Angeles 6
Nuremberg 6
Secaucus 6
Jiaxing 5
Dallas 4
Dublin 4
Seattle 4
Fuzhou 3
Monza 3
Naples 3
Shenzhen 3
Wuxi 3
Barcelona 2
Bologna 2
Cambridge 2
Hangzhou 2
Lanciano 2
Mainz 2
New York 2
San Francisco 2
Sassari 2
Tower Hamlets 2
Turin 2
Washington 2
Xi'an 2
Amsterdam 1
Bad Muenstereifel 1
Biggleswade 1
Colchester 1
Fontana 1
Formia 1
Landshut 1
Olomouc 1
Paris 1
Rockville 1
S. Pietro 1
Shimotsuke 1
Totale 402
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Nome #
In vivo Gene Therapy to the Liver and Nervous System: Promises and Challenges 27
Site-specific integration and tailoring of cassette design for sustainable gene transfer 27
null 26
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System 21
Exploring the identity and safety of hiPSC-derived neural stem/progenitor cells: implications for cell therapy approaches 20
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy 20
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 18
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS model 17
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 15
Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy 15
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 15
Dissecting the Transcriptional and Epigenetic Landscape of hiPSC-Derived Neural Stem and Progenitor Cells: Implications for Cell Therapy Approaches 14
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy 13
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy 13
Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases 12
Optimized bicistronic lentiviral vectors to correct b-hexosaminidase deficiency in neural and hematopoietic stem/progenitor cells and progeny 12
Generation of neuronal/glial mixed cultures from human induced pluripotent stem cells (hiPSCs) 12
In vitro Validation of Chimeric β-Galactosylceramidase Enzymes With Improved Enzymatic Activity and Increased Secretion 12
Genome-wide analyses of regulatory regions and transcripts in hiPSC-derived neural stem/progenitor cells to define their safety and efficacy in cell therapy approaches for neurological disorders 11
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 11
Intracerebroventricular transplantation of human iPSC-derived neural stem cells (hiPSC-NSCs) into neonatal mice 11
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes 10
Chimeric Lysosomal Enzymes with Improved Bioavailability to Advance Gene Therapy Strategies for Globoid Cell Leukodystrophy 10
Novel bicistronic lentiviral vectors correct β-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis 10
A Human IPSC-Based Model of Globoid Cell Leukodystrophy Uncovers Early Neurodevelopmental Defects 10
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 10
Adult neural stem cells 9
Integrated computational analysis highlights unique miRNA signatures in the subventricular zone and striatum of GM2 gangliosidosis animal models 9
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis 9
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 8
Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS 8
Composition and organization of the SCZ: A large germinal layer containing neural stem Cells in the adult mammalian brain 8
Clonal analyses and cryopreservation of neural stem cell cultures 8
Differential effects of CGRP on adenylyl cyclase in adult and embryonic rat brain 8
Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195 8
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models 8
Effect of hyperthermia on rhodamine 123 cytotoxicity in doxorubicin-sensitive and doxorubicin-resistant human breast carcinoma cell lines in vitro 7
Complete enzymatic correction of CNS tissue following intracerebral LV-mediated gene therapy in a murine model of GLD 7
Direct Intra-Brain LV-Mediated Gene Delivery Leads to Widespread Transgene Distribution and High-Level Enzymatic Correction in the Whole CNS of Twitcher Mice 7
Neuronal and glial cells derived from a murine model of GM2-gangliosidosis display typical hallmarks of pathology and represent a valuable model to test gene therapy strategies 7
Clonal analyses and cryopreservation of neural stem cell cultures 7
Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells 7
Lentiviral Vector Gene Transfer is limited by the proteasome at post-entry steps in various Types of Stem Cells 7
Isolation and Culture of Neural Stem/Progenitor Cells from the Postnatal Periventricular Region 7
Exploiting targeted epigenetic editing to increase the yield, homogeneity and purity of human iPSCderived oligodendrocyte cell populations 7
Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation 6
Adult neurogenesis in serotonin transporter deficient mice 6
Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: Relevance for in vivo cell tracking 6
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 6
Therapeutic advantages of combined gene/cell therapy strategies in a murine model of {GM}2 gangliosidosis 6
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors 6
Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche. 6
Modelling globoid cell leukodystrophy using integration-free human induced pluripotent stem cells (hiPSC) 5
Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb 5
Genome-wide definition of regulatory regions and transcripts during the transition from pluripotent to neural restricted stem cells 5
Plasma membrane-associated glycohydrolases along differentiation of murine neural stem cells 5
Early sulfatide storage and progressive neuronal and glial cell dysfunction revealed by human iPSC-based models of metachromatic leukodystrophy are rescued by lentiviral-mediated restoration of ARSA activity 5
Adult murine CNS stem cells express aquaporin channels 5
Perspective on innovative therapies for globoid cell leukodystrophy 5
Adult neural stem cells: Plasticity and developmental potential 5
Novel combined gene/cell therapy strategies to provide full rescue of the Sandhoff pathological phenotype 5
Patient-specific gene-corrected iPSC-derived neural stem/progenitor cells for autologous cell therapy applications in lysosomal storage diseases 5
Notch signaling in astrocytes and neuroblasts of the adult subventricular zone in health and after cortical injury 5
Human Neural Stem Cells Ameliorate Autoimmune Encephalomyelitis in Non-human Primates 5
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy 5
Neural Stem Cell Gene Therapy Ameliorates Pathology and Function in a Mouse Model of Globoid Cell Leukodystrophy 5
A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: Implication for metachromatic leukodystrophy diagnosis 5
Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene 5
Efficient lentiviral vector-mediated delivery of hARSA in the brain of juvenile non-human primates 5
Patient-specific induced pluripotent stem cells (iPSCs) to model metachromatic leukodystrophy 4
Therapeutic potential of genetically modified neural stem cells (NSCs) in a mouse model of Globoid Cell Leukodystrophy (GLD) 4
Short and medium-term influence of physical activity on immune parametersa 4
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system 4
Human brain endothelial cells and astrocytes produce IL-1β but not IL-10 4
NEURAL PRECURSOR CELL CULTURES FROM GM2-GANGLIOSIDOSIS MURINE MODELS RECAPITULATE THE BIOCHEMICAL HALLMARKS OF THE BRAIN PATHOLOGY 4
Skeletal myogenic potential of human and mouse neural stem cells 4
EFFICIENT LENTIVIRAL GENE DELIVERY TO SCHWANN CELLS 4
Effects of developmental age, brain region, and time in culture on long-term proliferation and multipotency of neural stem cell populations 4
Genome-Wide Definition of Regulatory Regions and Transcripts During the Transition from Pluripotent to Neural-Restricted Stem Cells 4
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells 4
The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-natal CNS development 4
Production of IL-10 in demyelinating inflammatory processes in the central nervous system [Cellule produttrici di IL-10 nei processi infiammatori demielinizzanti nel sistema nervoso centrale] 4
Neural stem cells: An overview 4
Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells 4
Robust generation of oligodendrocyte progenitors from human neural stem cells and engraftment in experimental demyelination models in mice 4
GENERATION OF SENSORY NEURONS AND SCHWANN CELLS FROM HUMAN-IPS CELLS OF CMT PATIENTS: A SUITABLE TOOL TO TEST NEW DEVELOPING DRUGS 4
Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor 4
Unique expression and localization of aquaporin- 4 and aquaporin-9 in murine and human neural stem cells and in their glial progeny 4
The insulin tolerance test and ovine corticotrophin-releasing-hormone test in episodic cluster headache ii: Comparison with low back pain patients 4
Gene delivery targeted to oligodendrocytes using a lentiviral vector 4
Neural precursor cell cultures from GM2-gangliosidosis murine models recapitulate the biochemical hallmarks of the brain pathology 4
Specific determination of β-galactocerebrosidase activity via competitive inhibition of β-galactosidase 3
Excitable properties in astrocytes derived from human embryonic CNS stem cells 3
Region- and age-dependent alterations of glial-neuronal metabolic interactions correlate with CNS pathology in a mouse model of globoid cell leukodystrophy 3
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential 3
Neural stem cells: Plasticity and their transdifferentiation potential 3
Isolate and culture precursor cells from the adult periventricular area 3
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents 3
Inorganic mercury changes the fate of murine CNS stem cells 3
Human iPSC-derived neural stem cells display a radial glia-like signaturein vitroand favorable long-term safety in transplanted mice 3
Totale 780
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Categoria #
all - tutte 11.708
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 11.708
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20224 0 0 0 4 0 0 0 0 0 0 0 0
2022/202393 30 12 3 0 0 18 8 7 2 4 9 0
2023/2024373 1 1 10 16 12 7 6 11 0 5 247 57
2024/2025338 165 8 26 98 41 0 0 0 0 0 0 0
Totale 813