IRIS
GRITTI, ANGELA
 Distribuzione geografica
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Continente #
AS - Asia 2.495
EU - Europa 2.393
NA - Nord America 1.688
SA - Sud America 416
AF - Africa 40
OC - Oceania 2
Continente sconosciuto - Info sul continente non disponibili 1
Totale 7.035
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Nazione #
RU - Federazione Russa 1.612
US - Stati Uniti d'America 1.595
SG - Singapore 1.008
CN - Cina 819
BR - Brasile 357
HK - Hong Kong 296
VN - Vietnam 195
IT - Italia 161
DE - Germania 154
FR - Francia 135
GB - Regno Unito 83
FI - Finlandia 57
CA - Canada 54
SE - Svezia 43
IN - India 35
NL - Olanda 32
MX - Messico 29
JP - Giappone 28
BD - Bangladesh 24
AR - Argentina 22
ES - Italia 21
ZA - Sudafrica 20
PL - Polonia 19
LT - Lituania 17
IQ - Iraq 16
AT - Austria 15
TR - Turchia 13
EC - Ecuador 11
UZ - Uzbekistan 11
CO - Colombia 10
IE - Irlanda 8
UA - Ucraina 8
ID - Indonesia 7
KE - Kenya 7
PK - Pakistan 7
PT - Portogallo 7
VE - Venezuela 6
GR - Grecia 5
BE - Belgio 4
IL - Israele 4
JO - Giordania 4
MY - Malesia 4
PH - Filippine 4
SA - Arabia Saudita 4
AZ - Azerbaigian 3
CH - Svizzera 3
CZ - Repubblica Ceca 3
EG - Egitto 3
ET - Etiopia 3
OM - Oman 3
PE - Perù 3
QA - Qatar 3
TT - Trinidad e Tobago 3
UY - Uruguay 3
AL - Albania 2
AU - Australia 2
BH - Bahrain 2
CL - Cile 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
JM - Giamaica 2
MA - Marocco 2
NP - Nepal 2
PY - Paraguay 2
AE - Emirati Arabi Uniti 1
BY - Bielorussia 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DM - Dominica 1
GA - Gabon 1
GT - Guatemala 1
HN - Honduras 1
HU - Ungheria 1
IR - Iran 1
PS - Palestinian Territory 1
SI - Slovenia 1
TN - Tunisia 1
XK - ???statistics.table.value.countryCode.XK??? 1
Totale 7.035
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Città #
Singapore 476
Moscow 315
San Jose 306
Ashburn 303
Hong Kong 292
Dallas 190
Beijing 143
Shanghai 130
Hefei 121
Lauterbourg 104
Ho Chi Minh City 65
New York 50
Los Angeles 48
Munich 46
Hanoi 43
Milan 40
São Paulo 40
Orem 35
Frankfurt am Main 34
Boardman 31
Helsinki 28
Turku 26
Nuremberg 24
Montreal 23
Pisa 22
Tokyo 22
Manchester 19
Atlanta 18
Denver 18
San Francisco 18
Santa Clara 17
Warsaw 17
Guangzhou 16
Houston 16
Johannesburg 15
London 15
Mexico City 15
Poplar 15
Amsterdam 14
Belo Horizonte 14
Falkenstein 14
Phoenix 14
Chennai 13
Lawrence 13
Princeton 13
Boston 12
Brooklyn 12
Charlotte 11
Da Nang 11
Chicago 10
Seattle 10
Toronto 10
Naples 9
Tashkent 9
Dublin 8
Rome 8
Secaucus 8
Washington 8
Jiaxing 7
Ribeirão Preto 7
Ankara 6
Baghdad 6
Brasília 6
Cambridge 6
Curitiba 6
Fortaleza 6
Nairobi 6
Ottawa 6
Rio de Janeiro 6
Shenzhen 6
Stockholm 6
Vienna 6
Biên Hòa 5
Buffalo 5
Bến Tre 5
Dhaka 5
Hải Dương 5
Mumbai 5
North Bergen 5
Paris 5
Quito 5
Amman 4
Athens 4
Bologna 4
Brussels 4
Cesano Boscone 4
Fuzhou 4
Goiânia 4
Guarulhos 4
Haiphong 4
Hangzhou 4
Lannion 4
Milwaukee 4
Ninh Bình 4
Pelotas 4
Shelburne 4
São Gonçalo 4
Tianjin 4
Turin 4
Addis Ababa 3
Totale 3.583
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Nome #
AAV vectors trigger DNA damage response-dependent pro-inflammatory signalling in human iPSC-derived CNS models and mouse brain 141
In vivo Gene Therapy to the Liver and Nervous System: Promises and Challenges 129
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 121
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 118
Exploring the identity and safety of hiPSC-derived neural stem/progenitor cells: implications for cell therapy approaches 103
Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System 102
Generation of Human Induced Pluripotent Stem Cell-Derived Bona Fide Neural Stem Cells for Ex Vivo Gene Therapy of Metachromatic Leukodystrophy 101
Human iPSC-derived neural stem cells display a radial glia-like signaturein vitroand favorable long-term safety in transplanted mice 100
Investigating the Role of Vector DNA Sensing and Transgene Expression on Innate Immune Signaling and Cell Toxicity upon AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 99
A Human IPSC-Based Model of Globoid Cell Leukodystrophy Uncovers Early Neurodevelopmental Defects 98
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 97
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 93
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 87
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 87
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS model 86
Genome-wide analyses of regulatory regions and transcripts in hiPSC-derived neural stem/progenitor cells to define their safety and efficacy in cell therapy approaches for neurological disorders 85
Generation of neuronal/glial mixed cultures from human induced pluripotent stem cells (hiPSCs) 85
Effect of hyperthermia on rhodamine 123 cytotoxicity in doxorubicin-sensitive and doxorubicin-resistant human breast carcinoma cell lines in vitro 84
Adult neural stem cells 84
Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy 84
Development of editing technologies for allele-specific silencing or precise correction of mutation hotspots affecting Alexander disease's patients 84
Human iPSC-Based Models for the Development of Therapeutics Targeting Neurodegenerative Lysosomal Storage Diseases 83
Isolation and Culture of Neural Stem/Progenitor Cells from the Postnatal Periventricular Region 82
Dissecting the Transcriptional and Epigenetic Landscape of hiPSC-Derived Neural Stem and Progenitor Cells: Implications for Cell Therapy Approaches 80
Chimeric Lysosomal Enzymes with Improved Bioavailability to Advance Gene Therapy Strategies for Globoid Cell Leukodystrophy 79
Developing Allele-Specific Gene Editing Technologies for Silencing or Precise Correction of GFAP Mutations Causing Alexander's Disease 79
Clonal analyses and cryopreservation of neural stem cell cultures 77
Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy 77
Adult neurogenesis in serotonin transporter deficient mice 76
Improving gene therapy approaches for globoid cell leukodystrophy: pre-clinical testing of chimeric GALC enzymes with enhanced bioavailability in human neural and hematopoietic cells 75
Human iPSC-derived neural stem cells displaying radial glia signature exhibit long-term safety in mice 75
Human iPSC-based neurodevelopmental models of globoid cell leukodystrophy uncover patient- and cell type-specific disease phenotypes 75
Intracerebroventricular transplantation of human iPSC-derived neural stem cells (hiPSC-NSCs) into neonatal mice 75
Investigating the Role of Innate Immune Signaling in AAV-Mediated Gene Transfer in hiPSC-Derived CNS Models 74
Clonal analyses and cryopreservation of neural stem cell cultures 74
Complete enzymatic correction of CNS tissue following intracerebral LV-mediated gene therapy in a murine model of GLD 73
Development of cutting-edge editing technologies to treat Alexander disease 73
A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: Implication for metachromatic leukodystrophy diagnosis 73
Adult neural stem cells: Plasticity and developmental potential 72
Basic fibroblast growth factor supports the proliferation of epidermal growth factor-generated neuronal precursor cells of the adult mouse CNS 71
Adult murine CNS stem cells express aquaporin channels 69
Efficient in vitro labeling of human neural precursor cells with superparamagnetic iron oxide particles: Relevance for in vivo cell tracking 69
Site-specific integration and tailoring of cassette design for sustainable gene transfer 68
Composition and organization of the SCZ: A large germinal layer containing neural stem Cells in the adult mammalian brain 67
Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy 65
Novel bicistronic lentiviral vectors correct β-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis 64
In vitro Validation of Chimeric β-Galactosylceramidase Enzymes With Improved Enzymatic Activity and Increased Secretion 64
Production of IL-10 in demyelinating inflammatory processes in the central nervous system [Cellule produttrici di IL-10 nei processi infiammatori demielinizzanti nel sistema nervoso centrale] 63
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 63
Defective postnatal neurogenesis and disorganization of the rostral migratory stream in absence of the Vax1 homeobox gene 63
Lentiviral Vector Gene Transfer is limited by the proteasome at post-entry steps in various Types of Stem Cells 62
Neural stem cells: An overview 60
Chimeric enzymes enhance treatment potential for globoid cell leukodystrophy through hematopoietic stem cell gene therapy 57
Investigating the role of innate immune signaling in cell toxicity upon AAV-mediated gene transfer in hiPSC-derived CNS models 56
Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells 56
Optimized bicistronic lentiviral vectors to correct b-hexosaminidase deficiency in neural and hematopoietic stem/progenitor cells and progeny 55
Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195 54
Human brain endothelial cells and astrocytes produce IL-1β but not IL-10 53
Direct Intra-Brain LV-Mediated Gene Delivery Leads to Widespread Transgene Distribution and High-Level Enzymatic Correction in the Whole CNS of Twitcher Mice 53
Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis 53
Therapeutic potential of genetically modified neural stem cells (NSCs) in a mouse model of Globoid Cell Leukodystrophy (GLD) 50
Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation 50
Neuronal and glial cells derived from a murine model of GM2-gangliosidosis display typical hallmarks of pathology and represent a valuable model to test gene therapy strategies 50
Integrated computational analysis highlights unique miRNA signatures in the subventricular zone and striatum of GM2 gangliosidosis animal models 50
Isolation and intracerebral grafting of nontransformed multipotential embryonic human CNS stem cells 50
Emx2 regulates the proliferation of stem cells of the adult mammalian central nervous system 49
Soluble or bound laminin elicit in human neuroblastoma cells short- or long-term potentiation of a K+ inwardly rectifying current: Relevance to neuritogenesis 49
Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential 49
Regulation of neuronal differentiation in human CNS stem cell progeny by leukemia inhibitory factor 49
Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche. 49
Patient-specific gene-corrected iPSC-derived neural stem/progenitor cells for autologous cell therapy applications in lysosomal storage diseases 48
Serotonin depletion hampers survival and proliferation in neurospheres derived from adult neural stem cells 48
Skeletal myogenic potential of human and mouse neural stem cells 47
Widespread enzymatic correction of CNS tissues by a single intracerebral injection of therapeutic lentiviral vector in leukodystrophy mouse models 47
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma 45
Neural stem cells: Plasticity and their transdifferentiation potential 45
Differential effects of CGRP on adenylyl cyclase in adult and embryonic rat brain 45
Gene therapy for lysosomal storage disorders 45
Patient-specific induced pluripotent stem cells (iPSCs) to model metachromatic leukodystrophy 44
Perspective on innovative therapies for globoid cell leukodystrophy 44
Gene delivery targeted to oligodendrocytes using a lentiviral vector 44
Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy 44
Neural Stem Cell Gene Therapy Ameliorates Pathology and Function in a Mouse Model of Globoid Cell Leukodystrophy 44
Exploiting targeted epigenetic editing to increase the yield, homogeneity and purity of human iPSCderived oligodendrocyte cell populations 44
Genome-wide definition of regulatory regions and transcripts during the transition from pluripotent to neural restricted stem cells 43
Early sulfatide storage and progressive neuronal and glial cell dysfunction revealed by human iPSC-based models of metachromatic leukodystrophy are rescued by lentiviral-mediated restoration of ARSA activity 43
Therapeutic advantages of combined gene/cell therapy strategies in a murine model of {GM}2 gangliosidosis 43
The neural stem cells and their transdifferentiation capacity 43
Plasma membrane-associated glycohydrolases along differentiation of murine neural stem cells 42
Genome-Wide Definition of Regulatory Regions and Transcripts During the Transition from Pluripotent to Neural-Restricted Stem Cells 42
The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-natal CNS development 42
Multipotent neural stem cells reside into the rostral extension and olfactory bulb of adult rodents 42
Robust in vivo gene transfer into adult mammalian neural stem cells by lentiviral vectors 42
Modelling globoid cell leukodystrophy using integration-free human induced pluripotent stem cells (hiPSC) 41
Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology 41
Inorganic mercury changes the fate of murine CNS stem cells 41
Excitable properties in astrocytes derived from human embryonic CNS stem cells 40
EFFICIENT LENTIVIRAL GENE DELIVERY TO SCHWANN CELLS 40
Region- and age-dependent alterations of glial-neuronal metabolic interactions correlate with CNS pathology in a mouse model of globoid cell leukodystrophy 40
GENERATION OF SENSORY NEURONS AND SCHWANN CELLS FROM HUMAN-IPS CELLS OF CMT PATIENTS: A SUITABLE TOOL TO TEST NEW DEVELOPING DRUGS 39
Totale 6.518
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Categoria #
all - tutte 33.844
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 33.844
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20224 0 0 0 4 0 0 0 0 0 0 0 0
2022/202393 30 12 3 0 0 18 8 7 2 4 9 0
2023/2024373 1 1 10 16 12 7 6 11 0 5 247 57
2024/20251.727 165 8 26 98 82 135 295 192 307 113 145 161
2025/20265.015 475 337 237 634 455 149 583 397 1.372 283 92 1
Totale 7.217