IRIS
LOMBARDO, ANGELO LEONE
 Distribuzione geografica
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Continente #
EU - Europa 1.830
NA - Nord America 1.828
AS - Asia 1.613
SA - Sud America 282
Continente sconosciuto - Info sul continente non disponibili 171
AF - Africa 41
OC - Oceania 2
Totale 5.767
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Nazione #
US - Stati Uniti d'America 1.735
RU - Federazione Russa 1.064
CN - Cina 539
SG - Singapore 529
BR - Brasile 228
HK - Hong Kong 219
SE - Svezia 197
IT - Italia 187
VN - Vietnam 137
DE - Germania 96
FR - Francia 78
GB - Regno Unito 62
CA - Canada 48
BD - Bangladesh 37
IN - India 37
MX - Messico 26
PL - Polonia 23
ZA - Sudafrica 23
FI - Finlandia 21
AT - Austria 19
NL - Olanda 19
ES - Italia 18
IQ - Iraq 18
JP - Giappone 18
AR - Argentina 15
ID - Indonesia 14
CO - Colombia 12
EC - Ecuador 10
IE - Irlanda 9
LT - Lituania 9
PK - Pakistan 9
TR - Turchia 8
IR - Iran 6
MA - Marocco 6
PT - Portogallo 6
VE - Venezuela 6
CH - Svizzera 5
IL - Israele 5
JM - Giamaica 5
AE - Emirati Arabi Uniti 4
MY - Malesia 4
NP - Nepal 4
SA - Arabia Saudita 4
TH - Thailandia 4
BB - Barbados 3
BG - Bulgaria 3
CR - Costa Rica 3
KE - Kenya 3
PY - Paraguay 3
TN - Tunisia 3
UA - Ucraina 3
UY - Uruguay 3
AU - Australia 2
AZ - Azerbaigian 2
BE - Belgio 2
CL - Cile 2
EG - Egitto 2
HN - Honduras 2
HR - Croazia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MK - Macedonia 2
NI - Nicaragua 2
PE - Perù 2
UZ - Uzbekistan 2
AL - Albania 1
AM - Armenia 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GD - Grenada 1
GT - Guatemala 1
GY - Guiana 1
IM - Isola di Man 1
JO - Giordania 1
KR - Corea 1
LB - Libano 1
PA - Panama 1
PH - Filippine 1
PS - Palestinian Territory 1
RO - Romania 1
RS - Serbia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
Totale 5.596
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Città #
Ashburn 279
Singapore 256
Moscow 239
Hong Kong 212
Dallas 207
San Jose 197
New York 100
Beijing 97
Shanghai 94
Council Bluffs 86
Hefei 66
Los Angeles 59
Lauterbourg 57
Milan 56
Lawrence 47
Princeton 47
Ho Chi Minh City 41
Hanoi 35
Orem 33
Phoenix 31
Washington 31
Munich 27
Santa Clara 24
São Paulo 24
Boardman 23
Warsaw 21
Nuremberg 20
Denver 19
Montreal 18
Brooklyn 16
Tokyo 16
Johannesburg 15
San Francisco 15
Stockholm 15
Atlanta 14
Houston 14
Chennai 13
Rome 13
The Dalles 13
Boston 12
Guangzhou 12
Mexico City 11
Seattle 11
Toronto 11
Da Nang 10
Helsinki 10
Poplar 10
Baghdad 9
Chicago 9
Falkenstein 9
London 9
Manchester 9
Turku 9
Frankfurt am Main 8
Haiphong 8
Jiaxing 8
Perugia 8
Bogotá 7
Dublin 7
Hangzhou 7
Mumbai 7
Philadelphia 7
Shenzhen 7
Amsterdam 6
Curitiba 6
New Delhi 6
Rio de Janeiro 6
The Bronx 6
Vienna 6
Charlotte 5
Columbus 5
Monza 5
Barcelona 4
Belo Horizonte 4
Bologna 4
Genoa 4
Kingston 4
Lannion 4
Naples 4
Omaha 4
Ottawa 4
Reston 4
Rishon LeTsiyyon 4
Salvador 4
Tianjin 4
Xi'an 4
Zhengzhou 4
Ankara 3
Annapolis 3
Aveiro 3
Bangkok 3
Berlin 3
Biggleswade 3
Birmingham 3
Bridgetown 3
Buffalo 3
Cairo 3
Caraguatatuba 3
Cleveland 3
Dhaka 3
Totale 2.955
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Nome #
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering 149
In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing 148
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 146
miR-126 identifies a quiescent and chemo-resistant human B-ALL cell subset that correlates with minimal residual disease 122
A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice 121
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 120
Permanent Epigenetic Gene Silencing 116
Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors 115
Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement 114
An unbiased genome-wide analysis of zinc-finger nuclease specificity 113
SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS 112
null 112
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 110
GENE SILENCING 108
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION 105
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches 103
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 103
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 103
Durable and efficient gene silencing in vivo by hit-and-run epigenome editing 102
A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels 101
Genome editing: a tool for research and therapy: Targeted genome editing hits the clinic 100
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 96
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 95
Altered Cl− homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability 95
Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis 92
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells 88
iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF 87
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 85
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 84
Engineering of NK activating receptor ligands enhances immune compatibility of MHC-I-/- iPSC for cell therapy of type 1 diabetes 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 83
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy 83
VECTOR PRODUCTION 81
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 81
Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination. 81
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery 80
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose 79
Engineering of NK activating receptor ligands enhances immune compatibility of MHC-I-/- iPSC-derived β cells for cell therapy of type 1 diabetes 79
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 79
Methods and compositions for targeted integration 78
Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene 77
Site-specific integration and tailoring of cassette design for sustainable gene transfer 74
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1 74
In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors 73
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy 71
Targeted genome editing in human repopulating haematopoietic stem cells 70
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 70
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 67
Limited transgene immune response and long-term expression of human alpha-L-iduronidase in young adult mice with mucopolysaccharidosis type I by liver-directed gene therapy 67
Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis 65
Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector 64
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 64
Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency 62
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 62
Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy 62
Trattamento chirurgico della fibrillazione atriale associata a valvulopatia mitralica. “Maze Procedure” e chirurgia della mitrale. 61
Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice 61
Genomic instability in induced stem cells 60
Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients. 59
T Cell Receptor Gene Transfer into Naive and Central Memory Lymphocytes by Lentiviral Vectors for a Safe and Effective Adoptive Immune Therapy of Leukemia 58
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 58
Targeted gene therapy and cell reprogramming in Fanconi anemia 57
Targeted gene correction in osteopetrotic-induced pluripotent stem cells for the generation of functional osteoclasts 57
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity 56
Patient-Specific iPSC-Derived Endothelial Cells Provide Long-Term Phenotypic Correction of Hemophilia A 51
NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD 50
The immune response to lentiviral-delivered transgene is modulated in vivo by transgene expressing antigen presenting cells but not by CD4+CD25+ regulatory T cells 45
Selection of human hematopoietic stem cells bearing the intended functional edit by transient AND-gate reporters 13
Simultaneous orthogonal cell engineering by a single CRISPR-Cas9 polyfunctional editor 11
Intercepting YAP Activation in Prostate Cancer Blocks Neuroendocrine Progression 6
Role of S1PR1 in Modulating Airway Epithelial Responses to Pseudomonas aeruginosa in Cystic Fibrosis 6
Erratum: IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (Molecular Therapy (2017) 25(10) (2254–2269), (S1525001617303143), (10.1016/j.ymthe.2017.06.029)) 4
Totale 5.767
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Categoria #
all - tutte 31.360
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 31.360
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202232 0 0 0 19 2 0 5 0 3 0 0 3
2022/2023293 101 76 24 3 2 42 8 23 6 2 6 0
2023/2024348 2 15 38 59 41 99 4 21 2 11 16 40
2024/20251.156 93 16 29 79 74 106 196 114 183 82 86 98
2025/20263.495 262 242 221 481 363 118 289 262 946 147 69 95
2026/2027343 82 213 48 0 0 0 0 0 0 0 0 0
Totale 5.767