IRIS
LOMBARDO, ANGELO LEONE
 Distribuzione geografica
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Continente #
EU - Europa 1.779
AS - Asia 1.524
NA - Nord America 1.446
SA - Sud America 277
AF - Africa 41
OC - Oceania 2
Totale 5.069
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Nazione #
US - Stati Uniti d'America 1.380
RU - Federazione Russa 1.064
SG - Singapore 519
CN - Cina 503
BR - Brasile 226
HK - Hong Kong 216
SE - Svezia 197
IT - Italia 141
VN - Vietnam 132
DE - Germania 94
FR - Francia 78
GB - Regno Unito 61
CA - Canada 37
IN - India 34
MX - Messico 24
PL - Polonia 23
ZA - Sudafrica 23
FI - Finlandia 21
AT - Austria 19
ES - Italia 18
IQ - Iraq 18
JP - Giappone 18
NL - Olanda 17
AR - Argentina 15
BD - Bangladesh 14
ID - Indonesia 11
CO - Colombia 10
EC - Ecuador 9
IE - Irlanda 9
LT - Lituania 9
PK - Pakistan 9
TR - Turchia 8
IR - Iran 6
MA - Marocco 6
PT - Portogallo 6
VE - Venezuela 6
CH - Svizzera 5
IL - Israele 5
TH - Thailandia 4
AE - Emirati Arabi Uniti 3
BG - Bulgaria 3
KE - Kenya 3
MY - Malesia 3
NP - Nepal 3
PY - Paraguay 3
SA - Arabia Saudita 3
TN - Tunisia 3
UA - Ucraina 3
UY - Uruguay 3
AU - Australia 2
AZ - Azerbaigian 2
BE - Belgio 2
CL - Cile 2
EG - Egitto 2
HR - Croazia 2
KG - Kirghizistan 2
KZ - Kazakistan 2
MK - Macedonia 2
PE - Perù 2
AL - Albania 1
AM - Armenia 1
BB - Barbados 1
BH - Bahrain 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CY - Cipro 1
DK - Danimarca 1
DZ - Algeria 1
ET - Etiopia 1
GA - Gabon 1
GY - Guiana 1
IM - Isola di Man 1
JO - Giordania 1
KR - Corea 1
LB - Libano 1
NI - Nicaragua 1
PA - Panama 1
PS - Palestinian Territory 1
RO - Romania 1
RS - Serbia 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
UZ - Uzbekistan 1
Totale 5.069
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Città #
Ashburn 262
Singapore 251
Moscow 239
Hong Kong 210
Dallas 202
San Jose 126
Shanghai 93
New York 91
Beijing 89
Hefei 66
Lauterbourg 57
Los Angeles 54
Milan 51
Lawrence 47
Princeton 47
Ho Chi Minh City 38
Hanoi 35
Orem 33
Washington 30
Munich 27
São Paulo 24
Boardman 23
Warsaw 21
Nuremberg 20
Denver 19
Tokyo 16
Brooklyn 15
Johannesburg 15
Montreal 15
Stockholm 15
Chennai 13
Houston 13
San Francisco 13
The Dalles 13
Atlanta 12
Guangzhou 12
Santa Clara 12
Boston 11
Mexico City 11
Phoenix 11
Seattle 11
Toronto 11
Helsinki 10
Poplar 10
Baghdad 9
Council Bluffs 9
Falkenstein 9
London 9
Manchester 9
Turku 9
Da Nang 8
Frankfurt am Main 8
Haiphong 8
Jiaxing 8
Perugia 8
Chicago 7
Dublin 7
Hangzhou 7
Shenzhen 7
Amsterdam 6
Bogotá 6
Curitiba 6
Mumbai 6
New Delhi 6
Rio de Janeiro 6
Vienna 6
Columbus 5
Monza 5
Rome 5
Barcelona 4
Belo Horizonte 4
Bologna 4
Charlotte 4
Genoa 4
Lannion 4
Ottawa 4
Philadelphia 4
Reston 4
Rishon LeTsiyyon 4
Salvador 4
Tianjin 4
Xi'an 4
Zhengzhou 4
Ankara 3
Annapolis 3
Aveiro 3
Bangkok 3
Berlin 3
Biggleswade 3
Caraguatatuba 3
Dhaka 3
Ferrara 3
Franca 3
La Plata 3
Lyon 3
Manassas 3
Montevideo 3
Nairobi 3
Noisy-le-Sec 3
Nova Iguaçu 3
Totale 2.680
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Nome #
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering 137
In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing 129
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières syndrome astrocytes 117
A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice 117
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 116
miR-126 identifies a quiescent and chemo-resistant human B-ALL cell subset that correlates with minimal residual disease 113
Permanent Epigenetic Gene Silencing 108
SELECTION BY MEANS OF ARTIFICIAL TRANSACTIVATORS 107
Erratum: IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (Molecular Therapy (2017) 25(10) (2254–2269), (S1525001617303143), (10.1016/j.ymthe.2017.06.029)) 107
Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors 106
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 102
Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for β cell replacement 102
An unbiased genome-wide analysis of zinc-finger nuclease specificity 101
COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF HBV GENE EXPRESSION 100
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches 100
GENE SILENCING 100
Genome editing: a tool for research and therapy: Targeted genome editing hits the clinic 95
Durable and efficient gene silencing in vivo by hit-and-run epigenome editing 94
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 94
TRPML1 links lysosomal calcium to autophagosome biogenesis through the activation of the CaMKKβ/VPS34 pathway 89
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 89
Altered Cl− homeostasis hinders forebrain GABAergic interneuron migration in a mouse model of intellectual disability 89
Epigenome-editing strategies to enhance oligodendroglial differentiation from human induced pluripotent stem cells 86
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 82
Galectin-3 in Prostate Cancer Stem-Like Cells Is Immunosuppressive and Drives Early Metastasis 81
iPSC-derived neural precursors exert a neuroprotective role in immune-mediated demyelination via the secretion of LIF 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 77
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 77
Engineering of NK activating receptor ligands enhances immune compatibility of MHC-I-/- iPSC for cell therapy of type 1 diabetes 76
VECTOR PRODUCTION 76
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy 76
Engineering of NK activating receptor ligands enhances immune compatibility of MHC-I-/- iPSC-derived β cells for cell therapy of type 1 diabetes 75
Methods and compositions for targeted integration 75
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery 73
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 73
Deletion of a pseudogene within a fragile site triggers the oncogenic expression of the mitotic CCSER1 gene 69
Site-specific integration and tailoring of cassette design for sustainable gene transfer 68
Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination. 67
Targeted genome editing in human repopulating haematopoietic stem cells 66
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 66
Lipo-Xenopeptide Polyplexes for CRISPR/Cas9 based Gene editing at ultra-low dose 65
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next-generation human artificial chromosomes for Duchenne muscular dystrophy 65
In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors 64
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 63
Limited transgene immune response and long-term expression of human alpha-L-iduronidase in young adult mice with mucopolysaccharidosis type I by liver-directed gene therapy 63
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 62
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1 62
Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector 60
Trattamento chirurgico della fibrillazione atriale associata a valvulopatia mitralica. “Maze Procedure” e chirurgia della mitrale. 60
Leukocytes recruited by tumor-derived HMGB1 sustain peritoneal carcinomatosis 60
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 60
Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy 59
Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice 58
Genomic instability in induced stem cells 58
Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency 57
Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients. 56
T Cell Receptor Gene Transfer into Naive and Central Memory Lymphocytes by Lentiviral Vectors for a Safe and Effective Adoptive Immune Therapy of Leukemia 55
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 52
Targeted gene correction in osteopetrotic-induced pluripotent stem cells for the generation of functional osteoclasts 52
Targeted gene therapy and cell reprogramming in Fanconi anemia 50
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity 48
NY-ESO-1 Single Edited T Cells to Treat Multiple Myeloma without Inducing GvHD 46
Patient-Specific iPSC-Derived Endothelial Cells Provide Long-Term Phenotypic Correction of Hemophilia A 46
A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels 43
The immune response to lentiviral-delivered transgene is modulated in vivo by transgene expressing antigen presenting cells but not by CD4+CD25+ regulatory T cells 43
Totale 5.221
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Categoria #
all - tutte 26.854
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 26.854
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/202232 0 0 0 19 2 0 5 0 3 0 0 3
2022/2023293 101 76 24 3 2 42 8 23 6 2 6 0
2023/2024348 2 15 38 59 41 99 4 21 2 11 16 40
2024/20251.156 93 16 29 79 74 106 196 114 183 82 86 98
2025/20263.292 262 242 221 481 363 118 289 262 946 108 0 0
Totale 5.221