IRIS
NALDINI, LUIGI
 Distribuzione geografica
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Continente #
EU - Europa 1.482
NA - Nord America 1.341
AS - Asia 288
AF - Africa 10
OC - Oceania 8
SA - Sud America 4
Totale 3.133
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Nazione #
US - Stati Uniti d'America 1.330
SE - Svezia 1.018
IT - Italia 246
CN - Cina 160
FI - Finlandia 56
SG - Singapore 51
IE - Irlanda 36
IN - India 36
DE - Germania 33
RU - Federazione Russa 25
GB - Regno Unito 23
JP - Giappone 17
CA - Canada 11
NL - Olanda 10
FR - Francia 8
AU - Australia 7
ES - Italia 7
CH - Svizzera 6
TW - Taiwan 6
ET - Etiopia 5
HK - Hong Kong 5
KR - Corea 5
BE - Belgio 4
IR - Iran 4
AT - Austria 3
BR - Brasile 3
DZ - Algeria 3
BG - Bulgaria 2
ID - Indonesia 2
MK - Macedonia 2
PL - Polonia 2
AR - Argentina 1
EG - Egitto 1
NG - Nigeria 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
TR - Turchia 1
VN - Vietnam 1
Totale 3.133
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Città #
Princeton 316
Lawrence 315
Ashburn 177
Shanghai 132
New York 101
Milan 93
Boardman 63
Helsinki 55
Dublin 34
Washington 34
Pune 28
Singapore 22
Los Angeles 19
Seattle 13
Cambridge 10
Rome 8
Borås 7
Moscow 7
London 6
Monza 6
St Petersburg 6
Aksum 5
Barcelona 5
Brisbane 5
Tokyo 5
Brooklyn 4
Chevy Chase 4
Delhi 4
Genoa 4
Naaldwijk 4
Philadelphia 4
Pisa 4
Toronto 4
Verona 4
Villejuif 4
Algiers 3
Ancona 3
Bari 3
Bergamo 3
Berlin 3
Cinisello Balsamo 3
Florence 3
Gijang-gun 3
Gravina di Catania 3
Hanover 3
Loughton 3
Moorestown 3
Nantou City 3
Naples 3
Park City 3
San Francisco 3
Schaarbeek 3
Schafisheim 3
Trento 3
Vienna 3
Zhengzhou 3
Arezzo 2
Athlone 2
Aurora 2
Belluno 2
Berkeley 2
Bethesda 2
Bologna 2
Camden 2
Carugate 2
Cherry Hill 2
Chicago 2
Clusone 2
Como 2
Cortona 2
Council Bluffs 2
Davis 2
Dayton 2
Daytona Beach 2
Düsseldorf 2
Farmington 2
Frankfurt am Main 2
Fremont 2
Gatchina 2
Hong Kong 2
Hyderabad 2
Kingston upon Thames 2
Kyoto 2
Langhirano 2
Las Vegas 2
Lucca 2
Madrid 2
Mestre 2
Mountain View 2
Munich 2
Muttenz 2
Nerviano 2
New Castle 2
Newtown 2
Novara 2
Omsk 2
Orlando 2
Palo Alto 2
Paris 2
Parma 2
Totale 1.663
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 184
Genome editing: a tool for research and therapy: Targeted genome editing hits the clinic 46
Genotoxic effects of base and prime editing in human hematopoietic stem cells 44
Efficient gene editing of human long-term hematopoietic stem cells validated by clonal tracking 32
HEPATOCYTE GROWTH-FACTOR (HGF) STIMULATES THE TYROSINE KINASE-ACTIVITY OF THE RECEPTOR ENCODED BY THE PROTOONCOGENE C-MET 30
Laboratory-Scale Lentiviral Vector Production and Purification for Enhanced Ex Vivo and In Vivo Genetic Engineering 30
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming 29
Targeted inducible delivery of immunoactivating cytokines reprograms glioblastoma microenvironment and inhibits growth in mouse models 27
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 27
Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome 25
A microRNA-regulated lentiviral vector mediates stable correction of hemophilia B mice 23
Site-specific integration and tailoring of cassette design for sustainable gene transfer 23
An unbiased genome-wide analysis of zinc-finger nuclease specificity 22
Multiple Integrated Non-clinical Studies Predict the Safety of Lentivirus-Mediated Gene Therapy for β-Thalassemia 22
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access 22
Inheritable Silencing of Endogenous Genes by Hit-and-Run Targeted Epigenetic Editing 21
Gene-Based Immune Reprogramming Overcomes the Immunosuppressive Microenvironment of Liver Metastases and Enables Protective T Cell Responses 20
Gene therapy returns to centre stage 20
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia 20
Tie2-expressing Monocytes: Regulation by Hpoxia and angioprotein. 19
A Comeback for Gene Therapy 19
Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates 19
Gene Modification and Three-Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches 19
Activation of the protein-tyrosine kinase associated with the bombesin receptor complex in small cell lung carcinomas. 18
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 18
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 18
A Mechanistic Role For Mir-126, a Hematopoietic Stem Cell Microrna, In Acute Leukemias 18
In vivo macrophage engineering reshapes the tumor microenvironment leading to eradication of liver metastases 17
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs. 17
A New-Generation Stable Inducible Packaging Cell Line for Lentiviral Vectors 17
ENDOGENOUS MICRORNA CAN BE BROADLY EXPLOITED TO REGULATE TRANSGENE EXPRESSION ACCORDING TO TISSUE, LINEAGE AND DIFFERENTIATION STATE 17
Gene therapy for a mucopolysaccharidosis type I murine model with lentiviral-IDUA vector 17
'Advanced' generation lentivirruses as efficient vectors for cardiomyocyte gene transduction in vitro and in vivo 17
Liver-directed lentiviral gene therapy in a dog model of hemophilia B 17
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 17
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 17
Efficient gene delivery and targeted expression to hepatocytes in vivo by improved lentiviral vectors 17
Limited transgene immune response and long-term expression of human alpha-L-iduronidase in young adult mice with mucopolysaccharidosis type I by liver-directed gene therapy 17
Retrieval of vector integration sites from cell-free DNA 17
Hematopoietic stem-and progenitor-cell gene therapy for hurler syndrome 17
The EHA Research Roadmap: Hematopoietic Stem Cell Gene Therapy 17
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance 16
The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy 16
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 16
Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo 16
Angiopoietin 2 expression in the cornea and its control of corneal neovascularisation 16
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 16
Adopt a moratorium on heritable genome editing 16
WFH State-of-the-art paper 2020: In vivo lentiviral vector gene therapy for haemophilia 16
Choice of template delivery mitigates the genotoxic risk and adverse impact of editing in human hematopoietic stem cells 15
Targeted genome editing in human repopulating haematopoietic stem cells 15
A miRNA-Based System for Selecting and Maintaining the Pluripotent State in Human Induced Pluripotent Stem Cells 15
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 15
A FUNCTIONAL DOMAIN IN THE HEAVY-CHAIN OF SCATTER FACTOR HEPATOCYTE GROWTH-FACTOR BINDS THE C-MET RECEPTOR AND INDUCES CELL-DISSOCIATION BUT NOT MITOGENESIS 15
Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice 15
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 15
Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination. 15
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 15
Hyperfunctional coagulation factor IX improves the efficacy of gene therapy in hemophilic mice 15
Genomic instability in induced stem cells 15
Genome editing for scalable production of alloantigen-free lentiviral vectors for in vivo gene therapy 15
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 15
Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting 14
Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency 14
SCATTER FACTOR AND HEPATOCYTE GROWTH-FACTOR ARE INDISTINGUISHABLE LIGANDS FOR THE MET RECEPTOR 14
Safety of arylsulfatase A over-expression for gene therapy of metachromatic leukodystrophy 14
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 14
A MicroRNA-regulated and GP64-pseudotyped Lentiviral Vector Mediates Stable Expression of FVIII in a Murine Model of Hemophilia A 14
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery 14
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 14
Up to 10.5 Years of Follow-Up in 17 Subjects Treated with Hematopoietic Stem and Progenitor Cell Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome 13
Autologous Cell & Gene Therapy for the Therapeutic Targeting of Immune Payloads to the Solid Tumor Microenvironment: Preliminary Results of the TEM-GBM Study 13
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress 13
Mobilization-based chemotherapy-free engraftment of gene-edited human hematopoietic stem cells 13
MULTIPLY ATTENUATED LENTIVIRAL VECTOR ACHIEVES EFFICIENT GENE DELIVERY IN VIVO 13
In vitro gene therapy of mucopolysaccharidosis type I by lentiviral vectors 13
TYROSINES(1234-1235) ARE CRITICAL FOR ACTIVATION OF THE TYROSINE KINASE ENCODED BY THE MET PROTOONCOGENE (HGF RECEPTOR) 13
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 13
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs 13
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 13
Mouse Models To Assess the Risk of Vector Insertional Mutagenesis upon Systemic Delivery 13
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice 13
Hematopoietic Stem Cell Gene Transfer in a Tumor-Prone Mouse Model Uncovers Low Genotoxicity of Lentiviral Vector Integration 13
Modulation of immune responses in lentiviral vector-mediated gene transfer 13
miR-511-3p modulates genetic programs of tumor-associated macrophages 13
IFN gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment 13
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 13
MNK2 governs the macrophage antiinflammatory phenotype 13
null 13
GP64-pseudotyped lentiviral vectors target liver endothelial cells and correct hemophilia A mice 12
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IN VIVO GENE DELIVERY AND STABLE TRANSDUCTION OF NONDIVIDING CELLS BY A LENTIVIRAL VECTOR 12
Transcriptional targeting of lentiviral vectors by long terminal repeat enhancer replacement 12
Ex vivo gene transfer and correction for cell-based therapies 12
FcR gamma Activation Regulates Inflammation-Associated Squamous Carcinogenesis 12
A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice 12
Targeted gene therapy and cell reprogramming in Fanconi anemia 12
A human immunodeficiency virus type 1 pol gene-derived sequence (cPPT/CTS) increases the efficiency of transduction of human nondividing monocytes and T lymphocytes by lentiviral vectors 12
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. 12
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 12
Totale 1.867
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Categoria #
all - tutte 60.632
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.632
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202035 17 0 0 3 2 1 0 0 1 11 0 0
2020/202146 0 10 0 2 4 19 6 0 3 2 0 0
2021/2022207 1 0 0 116 10 11 12 13 12 11 5 16
2022/20231.795 700 431 128 15 11 227 49 126 61 14 19 14
2023/20241.164 42 62 138 132 116 218 43 89 10 64 74 176
2024/202511 11 0 0 0 0 0 0 0 0 0 0 0
Totale 3.422