IRIS
AIUTI, ALESSANDRO
 Distribuzione geografica
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Continente #
EU - Europa 1.667
NA - Nord America 1.270
AS - Asia 742
OC - Oceania 15
AF - Africa 12
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 3
Totale 3.715
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Nazione #
US - Stati Uniti d'America 1.259
SE - Svezia 804
IT - Italia 343
SG - Singapore 336
CN - Cina 311
RU - Federazione Russa 258
DE - Germania 61
FI - Finlandia 59
IE - Irlanda 49
IN - India 40
GB - Regno Unito 34
NL - Olanda 15
AU - Australia 13
FR - Francia 12
ES - Italia 10
CA - Canada 9
IR - Iran 9
TR - Turchia 9
JP - Giappone 8
IQ - Iraq 7
ET - Etiopia 5
KR - Corea 5
AT - Austria 4
BG - Bulgaria 4
BR - Brasile 4
PL - Polonia 4
BE - Belgio 3
DZ - Algeria 3
EU - Europa 3
IL - Israele 3
LV - Lettonia 3
MY - Malesia 3
AR - Argentina 2
HK - Hong Kong 2
ID - Indonesia 2
MX - Messico 2
NZ - Nuova Zelanda 2
PS - Palestinian Territory 2
VN - Vietnam 2
BD - Bangladesh 1
CI - Costa d'Avorio 1
CZ - Repubblica Ceca 1
EE - Estonia 1
EG - Egitto 1
MA - Marocco 1
MK - Macedonia 1
NG - Nigeria 1
OM - Oman 1
TW - Taiwan 1
UA - Ucraina 1
Totale 3.715
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Città #
Lawrence 270
Princeton 270
Singapore 216
Shanghai 158
Ashburn 129
Milan 121
New York 118
Moscow 95
Boardman 57
Helsinki 53
Dublin 47
Rome 25
Pune 23
Monza 19
Guangzhou 18
Hanover 18
Los Angeles 18
Washington 17
Dallas 16
Beijing 15
Seattle 15
London 14
Shenzhen 13
Brisbane 8
Kassel 8
Amsterdam 7
Perugia 7
Santa Clara 7
Reggio Emilia 6
Aksum 5
Cambridge 5
Hillah 5
Lappeenranta 5
Livorno 5
Rockville 5
San Jose 5
Brescia 4
Chevy Chase 4
Cornate d'Adda 4
Delhi 4
Hamburg 4
Michaelnbach 4
Naples 4
Paris 4
Philadelphia 4
Sydney 4
Verona 4
Wuhan 4
Wuxi 4
Xi'an 4
Algiers 3
Andover 3
Ankara 3
Badalona 3
Barcelona 3
Bethesda 3
Bologna 3
Borås 3
Cagliari 3
Castelseprio 3
Chandigarh 3
Chicago 3
Clifton 3
Ercolano 3
Gijang-gun 3
Hangzhou 3
Kuala Lumpur 3
Loughton 3
Moorestown 3
Park City 3
Riga 3
Secaucus 3
St Petersburg 3
Tokyo 3
Toronto 3
Athlone 2
Aurora 2
Barreiras 2
Belluno 2
Bengaluru 2
Berlin 2
Bisceglie 2
Boydton 2
Bristol 2
Brooklyn 2
Buenos Aires 2
Bursa 2
Campobasso 2
Casier 2
Cherry Hill 2
Council Bluffs 2
Crema 2
Dayton 2
Daytona Beach 2
Duhok 2
Düsseldorf 2
Elmendorf 2
Farmington 2
Florence 2
Formia 2
Totale 2.004
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 218
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 59
Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency 49
Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children 37
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 31
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access 29
Wiskott–Aldrich syndrome: Oral findings and microbiota in children and review of the literature 29
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice 28
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies 28
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 26
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis 26
Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency 26
ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell Transplantation 25
Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity 25
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 24
Bone marrow harvesting from paediatric patients undergoing haematopoietic stem cell gene therapy 24
A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection 24
Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients 24
B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients 23
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia 23
Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies 23
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs. 22
A Novel Assay in Whole Blood Demonstrates Restoration of Mitochondrial Activity in Phagocytes After Successful HSCT in Hyperinflamed X-Linked Chronic Granulomatous Disease 22
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 22
Linee Guida per la diagnosi e terapia dell’Immunodeficienza Comune Variabile 22
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 22
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 22
Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated BCGitis 22
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function 21
Pioglitazone as a novel therapeutic approach in chronic granulomatous disease 21
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy 20
A novel genomic inversion in Wiskott-Aldrich-associated autoinflammation 20
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate 20
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 20
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients 20
Urogenital Abnormalities in Adenosine Deaminase Deficiency 20
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity 20
Retrieval of vector integration sites from cell-free DNA 20
Hematopoietic stem-and progenitor-cell gene therapy for hurler syndrome 20
Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report 20
The EHA Research Roadmap: Hematopoietic Stem Cell Gene Therapy 20
A Case of Two Adult Brothers with Wiskott-Aldrich Syndrome, One Treated with Gene Therapy and One with HLA-Identical Hematopoietic Stem Cell Transplantation 20
A Prevalent CXCR3+ Phenotype of Circulating Follicular Helper T Cells Indicates Humoral Dysregulation in Children with Down Syndrome 20
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 19
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 19
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 19
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 19
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 19
Gene therapy using haematopoietic stem and progenitor cells 19
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 19
Evidence of Treatment Benefits in Patients with Mucopolysaccharidosis Type I-Hurler in Long-term Follow-up Using a New Magnetic Resonance Imaging Scoring System 19
Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series 19
Interleukin 7 production by bone marrow-derived stromal cells in HIV-1-infected patients during highly active antiretroviral therapy 18
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood 18
Leukocyte and Dried Blood Spot Arylsulfatase A Assay by Tandem Mass Spectrometry 18
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 18
Ex Vivo and In Vivo Gene Therapy for Mucopolysaccharidoses: State of the Art 18
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 18
Correction to: A Case of Two Adult Brothers with Wiskott‑Aldrich Syndrome, One Treated with Gene Therapy and One with HLA‑Identical Hematopoietic Stem Cell Transplantation (Journal of Clinical Immunology, (2022), 42, 2, (421-425), 10.1007/s10875-021-01157-6) 17
Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation 17
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 17
Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency 17
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) 17
Terapia genica e malattia ereditaria 17
A map of human circular RNAs in clinically relevant tissues 17
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 17
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 17
Third cranial nerve palsy in an 88-year-old man after SARS-CoV-2 mRNA vaccination: Change of injection site and type of vaccine resulted in an uneventful second dose with humoral immune response 17
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 17
Up to 10.5 Years of Follow-Up in 17 Subjects Treated with Hematopoietic Stem and Progenitor Cell Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome 16
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation 16
Spectrotype of anti-gp120 antibodies remains stable during the course of HIV disease 16
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH) 16
Control of human coagulation by recombinant serine proteases. Blood clotting is activated by recombinant factor XII deleted of five regulatory domains 16
Clinical applications of gene therapy for primary immunodeficiencies 16
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 16
A glimpse into the in vivo dynamics during immune reconstitution in ADA-SCID patients after gene therapy treatment 16
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 16
Impaired X-CGD T cell compartment is gp91phox-NADPH oxidase independent 16
Twenty-Five Years of Gene Therapy for ADA-SCID: From Bubble Babies to an Approved Drug 16
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 16
Neutrophils drive type-I interferon production and autoantibodies in Wiskott-Aldrich syndrome 16
JAK3 mutations in Italian patients affected by SCID: New molecular aspects of a long-known gene 16
Circulating follicular helper and follicular regulatory T cells are severely compromised in human CD40 deficiency: A case report 16
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 16
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 16
First case of patient with two homozygous mutations in MYD88 and CARD9 genes presenting with pyogenic bacterial infections, elevated IgE, and persistent EBV viremia 16
Clinical, immunological, and molecular features of typical and atypical severe combined immunodeficiency: Report of the italian primary immunodeficiency network 16
Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency 16
Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity 16
Immunosuppressive therapy in childhood‐onset arrhythmogenic inflammatory cardiomyopathy 16
Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006) 16
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 16
Persistence of circulating T-follicular helper cells after rituximab is associated with relapse of IgG4-related disease 16
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress 15
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 15
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 15
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 15
LENTIVIRAL VECTOR TRANSDUCED CD34+CELLS FOR THE TREATMENT OF WISKOTT-ALDRICH SYNDROME 15
The Role of Conditioning in Hematopoietic Stem-Cell Gene Therapy 15
Totale 2.213
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Categoria #
all - tutte 71.553
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 71.553
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202027 0 0 0 0 0 1 0 4 0 22 0 0
2020/202162 5 2 1 0 14 18 17 0 4 1 0 0
2021/2022228 1 0 2 62 19 9 17 16 31 52 13 6
2022/20231.630 607 346 108 26 21 194 61 104 85 22 26 30
2023/20241.104 83 56 117 114 89 201 44 87 9 53 62 189
2024/2025918 519 91 88 139 81 0 0 0 0 0 0 0
Totale 4.096