IRIS
AIUTI, ALESSANDRO
 Distribuzione geografica
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Continente #
NA - Nord America 8.722
EU - Europa 8.633
AS - Asia 7.455
SA - Sud America 1.858
Continente sconosciuto - Info sul continente non disponibili 605
AF - Africa 188
OC - Oceania 26
Totale 27.487
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Nazione #
US - Stati Uniti d'America 8.132
RU - Federazione Russa 4.165
SG - Singapore 2.604
CN - Cina 2.268
IT - Italia 2.032
BR - Brasile 1.516
HK - Hong Kong 892
SE - Svezia 843
VN - Vietnam 710
FR - Francia 350
DE - Germania 328
BD - Bangladesh 292
CA - Canada 277
GB - Regno Unito 237
IN - India 186
AR - Argentina 136
AT - Austria 102
FI - Finlandia 100
NL - Olanda 92
MX - Messico 91
PL - Polonia 87
ES - Italia 82
ID - Indonesia 71
JP - Giappone 69
EC - Ecuador 66
ZA - Sudafrica 66
IQ - Iraq 63
TR - Turchia 63
IE - Irlanda 57
JM - Giamaica 42
CO - Colombia 41
CR - Costa Rica 38
UA - Ucraina 33
MY - Malesia 31
VE - Venezuela 27
HN - Honduras 25
AU - Australia 23
LT - Lituania 23
MA - Marocco 23
TT - Trinidad e Tobago 23
UZ - Uzbekistan 22
UY - Uruguay 20
EG - Egitto 17
NI - Nicaragua 17
PY - Paraguay 17
TN - Tunisia 17
GT - Guatemala 16
PK - Pakistan 16
SA - Arabia Saudita 16
SV - El Salvador 16
AE - Emirati Arabi Uniti 15
BE - Belgio 15
CL - Cile 15
JO - Giordania 15
DZ - Algeria 14
IR - Iran 14
RO - Romania 14
KE - Kenya 13
NP - Nepal 13
KR - Corea 12
PE - Perù 12
CH - Svizzera 11
IL - Israele 11
PR - Porto Rico 11
PH - Filippine 10
ET - Etiopia 8
GP - Guadalupe 8
AZ - Azerbaigian 7
BG - Bulgaria 7
CZ - Repubblica Ceca 7
LB - Libano 7
MD - Moldavia 7
NG - Nigeria 7
TW - Taiwan 7
GR - Grecia 6
AL - Albania 5
CI - Costa d'Avorio 5
CY - Cipro 5
EE - Estonia 5
LV - Lettonia 5
PS - Palestinian Territory 5
SY - Repubblica araba siriana 5
TH - Thailandia 5
BH - Bahrain 4
BO - Bolivia 4
DO - Repubblica Dominicana 4
GD - Grenada 4
RS - Serbia 4
SN - Senegal 4
CG - Congo 3
CU - Cuba 3
CW - ???statistics.table.value.countryCode.CW??? 3
DK - Danimarca 3
EU - Europa 3
GY - Guiana 3
KH - Cambogia 3
KW - Kuwait 3
KZ - Kazakistan 3
MT - Malta 3
PA - Panama 3
Totale 26.843
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Città #
Ashburn 1.203
Singapore 1.124
San Jose 947
Moscow 906
Hong Kong 880
Dallas 794
Milan 507
Shanghai 445
Council Bluffs 442
New York 331
Hefei 326
Beijing 304
Princeton 273
Lauterbourg 270
Lawrence 269
Ho Chi Minh City 235
Los Angeles 197
Santa Clara 193
Rome 177
Hanoi 160
Phoenix 157
São Paulo 129
Nuremberg 86
Helsinki 69
Miano 69
Brooklyn 67
Brescia 66
Warsaw 66
Atlanta 65
Orem 64
Munich 63
Boardman 62
Naples 59
Chicago 56
Denver 56
Tokyo 55
Cesano Boscone 54
Dublin 53
Montreal 51
Rio de Janeiro 50
Chennai 46
Houston 46
Toronto 46
Vienna 45
London 44
Guangzhou 43
Haiphong 43
Stockholm 42
Frankfurt am Main 41
Johannesburg 39
Brasília 38
Mexico City 38
Boston 37
Turin 37
Poplar 36
The Dalles 36
Buffalo 35
Florence 30
Seattle 30
Washington 30
Bologna 29
Curitiba 29
Guayaquil 29
Amsterdam 27
Manchester 26
Mumbai 26
San José 26
Ankara 24
Kingston 24
Monza 24
Pune 24
Belo Horizonte 23
Porto Alegre 23
Da Nang 22
Shenzhen 22
San Francisco 21
Tashkent 21
Guarulhos 20
Salvador 20
Baghdad 19
Genoa 19
North Bergen 19
Philadelphia 19
Turku 19
Tianjin 18
Hanover 17
Kuala Lumpur 17
Miami 17
Paris 17
Biên Hòa 16
Charlotte 16
Hải Dương 16
Managua 16
Sorocaba 16
Bari 15
Cambridge 15
Dhaka 15
Las Vegas 15
Omaha 15
Quito 15
Totale 12.973
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 456
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 297
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access 264
Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children 209
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress 198
In vivo haemopoietic stem cell gene therapy enabled by postnatal trafficking 198
A case of T-cell acute lymphoblastic leukemia in retroviral gene therapy for ADA-SCID 185
Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency 169
A Novel Assay in Whole Blood Demonstrates Restoration of Mitochondrial Activity in Phagocytes After Successful HSCT in Hyperinflamed X-Linked Chronic Granulomatous Disease 166
A GLB1 transgene with enhanced therapeutic potential for the preclinical development of ex-vivo gene therapy to treat mucopolysaccharidosis type IVB 165
A novel STING variant triggers endothelial toxicity and SAVI disease 160
Genetic determinants of type 1 diabetes in individuals with weak evidence of islet autoimmunity at disease onset 159
Long-term lineage commitment in haematopoietic stem cell gene therapy 155
Effects of atidarsagene autotemcel gene therapy on peripheral nerves in late-infantile metachromatic leukodystrophy 154
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 154
Bone marrow harvesting from paediatric patients undergoing haematopoietic stem cell gene therapy 150
Hematopoietic stem-and progenitor-cell gene therapy for hurler syndrome 149
Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency 146
A novel genomic inversion in Wiskott-Aldrich-associated autoinflammation 143
Early skeletal outcomes after hematopoietic stem and progenitor cell gene therapy for Hurler syndrome 141
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 141
Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series 137
ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell Transplantation 135
Ex Vivo and In Vivo Gene Therapy for Mucopolysaccharidoses: State of the Art 135
Long-term and real-world safety and efficacy of retroviral gene therapy for adenosine deaminase deficiency 134
Long-Term Effects of Atidarsagene Autotemcel for Metachromatic Leukodystrophy 134
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 132
A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection 130
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 129
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function 128
Access to gene therapy for rare diseases when commercialization is not fit for purpose 127
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths 127
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 126
Wiskott–Aldrich syndrome: Oral findings and microbiota in children and review of the literature 125
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 124
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity 124
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies 123
Human genetic and immunological determinants of critical COVID-19 pneumonia 121
B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients 120
A Prevalent CXCR3+ Phenotype of Circulating Follicular Helper T Cells Indicates Humoral Dysregulation in Children with Down Syndrome 120
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 119
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 119
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy 118
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 118
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 118
Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients 118
Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity 118
Autoantibodies against type I IFNs in humans with alternative NF-κB pathway deficiency 118
Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report 117
Mechanisms of hematopoietic clonal dominance in VEXAS syndrome 116
A prospective study on the natural history of patients with profound combined immunodeficiency: An interim analysis 116
A Case of Two Adult Brothers with Wiskott-Aldrich Syndrome, One Treated with Gene Therapy and One with HLA-Identical Hematopoietic Stem Cell Transplantation 116
Up to 10.5 Years of Follow-Up in 17 Subjects Treated with Hematopoietic Stem and Progenitor Cell Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome 115
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 115
Targeted NGS platforms for genetic screening and gene discovery in primary immunodeficiencies 114
A glimpse into the in vivo dynamics during immune reconstitution in ADA-SCID patients after gene therapy treatment 112
Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies 112
Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes 112
Pioglitazone as a novel therapeutic approach in chronic granulomatous disease 111
Retrieval of vector integration sites from cell-free DNA 111
Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders 111
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 110
Correction to: A Case of Two Adult Brothers with Wiskott‑Aldrich Syndrome, One Treated with Gene Therapy and One with HLA‑Identical Hematopoietic Stem Cell Transplantation (Journal of Clinical Immunology, (2022), 42, 2, (421-425), 10.1007/s10875-021-01157-6) 109
Clinical, immunological, and molecular features of typical and atypical severe combined immunodeficiency: Report of the italian primary immunodeficiency network 109
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients 108
Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency 108
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 107
Auto-antibodies against type I IFNs in patients with life-threatening COVID-19 105
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) 104
Genetic engineering meets hematopoietic stem cell biology for next-generation gene therapy 103
Defective B cell tolerance due to adenosine deaminase deficiency is corrected by gene therapy 103
Gene therapy using haematopoietic stem and progenitor cells 103
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis 103
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice 102
Advances in stem cell research and therapeutic development 102
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 101
A map of human circular RNAs in clinically relevant tissues 101
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 100
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 100
Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity 99
Immunosuppressive therapy in childhood‐onset arrhythmogenic inflammatory cardiomyopathy 99
Natural history of type 1 diabetes on an immunodysregulatory background with genetic alteration in B-cell activating factor receptor: A case report 98
Relevance of an Academic GMP Pan-European Vector Infra-structure (PEVI) 98
Severe West Nile Virus and Severe Acute Respiratory Syndrome Coronavirus 2 Infections in a Patient With Thymoma and Anti–Type I Interferon Antibodies 97
Circulating follicular helper and follicular regulatory T cells are severely compromised in human CD40 deficiency: A case report 97
Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated BCGitis 97
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate 96
Third cranial nerve palsy in an 88-year-old man after SARS-CoV-2 mRNA vaccination: Change of injection site and type of vaccine resulted in an uneventful second dose with humoral immune response 96
Hematopoietic stem cell transplantation for Wiskott-Aldrich syndrome: an EBMT Inborn Errors Working Party analysis. 96
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 95
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 95
Evidence of Treatment Benefits in Patients with Mucopolysaccharidosis Type I-Hurler in Long-term Follow-up Using a New Magnetic Resonance Imaging Scoring System 95
The quality of life of children and adolescents with X-linked agammaglobulinemia 94
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 93
Expanded circulating hematopoietic stem/progenitor cells as novel cell source for the treatment of TCIRG1 osteopetrosis 93
The EHA Research Roadmap: Hematopoietic Stem Cell Gene Therapy 93
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs. 92
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 91
Urogenital Abnormalities in Adenosine Deaminase Deficiency 91
Advanced cell-based therapies for the treatment of primary immunodeficiency (Cell-PID) 89
Totale 12.686
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Categoria #
all - tutte 164.283
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 164.283
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022222 0 0 0 62 19 6 17 16 31 52 13 6
2022/20231.620 604 344 107 25 21 193 60 103 85 22 26 30
2023/20241.102 83 56 117 114 89 199 44 87 9 53 62 189
2024/20254.618 519 91 88 138 142 346 580 533 793 603 349 436
2025/202614.932 1.004 1.055 1.163 2.131 955 518 1.315 1.072 3.790 884 482 563
2026/20274.774 702 1.069 1.014 1.989 0 0 0 0 0 0 0 0
Totale 27.487