IRIS
AIUTI, ALESSANDRO
 Distribuzione geografica
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Continente #
EU - Europa 1.568
NA - Nord America 1.216
AS - Asia 492
OC - Oceania 13
AF - Africa 11
SA - Sud America 6
Continente sconosciuto - Info sul continente non disponibili 3
Totale 3.309
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Nazione #
US - Stati Uniti d'America 1.205
SE - Svezia 802
IT - Italia 284
SG - Singapore 260
RU - Federazione Russa 258
CN - Cina 160
FI - Finlandia 54
DE - Germania 49
IE - Irlanda 49
IN - India 33
GB - Regno Unito 28
AU - Australia 11
FR - Francia 10
CA - Canada 9
ES - Italia 9
NL - Olanda 8
IR - Iran 7
JP - Giappone 6
TR - Turchia 6
ET - Etiopia 5
IQ - Iraq 5
KR - Corea 5
AT - Austria 4
BR - Brasile 4
BE - Belgio 3
DZ - Algeria 3
EU - Europa 3
LV - Lettonia 3
MY - Malesia 3
AR - Argentina 2
BG - Bulgaria 2
HK - Hong Kong 2
ID - Indonesia 2
MX - Messico 2
NZ - Nuova Zelanda 2
PL - Polonia 2
BD - Bangladesh 1
CI - Costa d'Avorio 1
CZ - Repubblica Ceca 1
EG - Egitto 1
IL - Israele 1
MK - Macedonia 1
NG - Nigeria 1
TW - Taiwan 1
UA - Ucraina 1
Totale 3.309
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Città #
Lawrence 270
Princeton 270
Singapore 158
Shanghai 133
Ashburn 129
New York 118
Milan 113
Moscow 95
Boardman 57
Helsinki 52
Dublin 47
Pune 23
Rome 19
Hanover 18
Washington 16
Los Angeles 15
Seattle 15
London 13
Brisbane 8
Perugia 7
Reggio Emilia 6
Aksum 5
Beijing 5
Cambridge 5
Hillah 5
Livorno 5
Rockville 5
San Jose 5
Amsterdam 4
Brescia 4
Chevy Chase 4
Cornate d'Adda 4
Delhi 4
Michaelnbach 4
Monza 4
Philadelphia 4
Santa Clara 4
Verona 4
Algiers 3
Andover 3
Badalona 3
Barcelona 3
Bethesda 3
Bologna 3
Borås 3
Cagliari 3
Castelseprio 3
Clifton 3
Ercolano 3
Gijang-gun 3
Kuala Lumpur 3
Loughton 3
Moorestown 3
Park City 3
Riga 3
Secaucus 3
St Petersburg 3
Toronto 3
Athlone 2
Aurora 2
Barreiras 2
Belluno 2
Berlin 2
Bisceglie 2
Bristol 2
Brooklyn 2
Buenos Aires 2
Bursa 2
Campobasso 2
Casier 2
Cherry Hill 2
Chicago 2
Council Bluffs 2
Crema 2
Dayton 2
Daytona Beach 2
Düsseldorf 2
Elmendorf 2
Farmington 2
Gustavo Adolfo Madero 2
Hamilton 2
Hangzhou 2
Hong Kong 2
Hyderabad 2
Kingston upon Thames 2
Langhirano 2
Lappeenranta 2
Las Vegas 2
Laurel 2
Limbiate 2
Madrid 2
Malnate 2
Merkez 2
Milwaukee 2
Mountain View 2
Newtown 2
North Canton 2
Orlando 2
Palo Alto 2
Paris 2
Totale 1.801
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 193
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 58
Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency 46
Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children 28
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies 27
Wiskott–Aldrich syndrome: Oral findings and microbiota in children and review of the literature 26
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 25
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 25
Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency 25
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice 24
Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity 23
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia 22
ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell Transplantation 22
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 22
Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies 22
A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection 22
Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients 22
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access 22
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis 22
Linee Guida per la diagnosi e terapia dell’Immunodeficienza Comune Variabile 21
B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients 21
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 20
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 20
Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated BCGitis 20
Pioglitazone as a novel therapeutic approach in chronic granulomatous disease 20
Bone marrow harvesting from paediatric patients undergoing haematopoietic stem cell gene therapy 19
Urogenital Abnormalities in Adenosine Deaminase Deficiency 19
Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report 19
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs. 18
A Novel Assay in Whole Blood Demonstrates Restoration of Mitochondrial Activity in Phagocytes After Successful HSCT in Hyperinflamed X-Linked Chronic Granulomatous Disease 18
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate 18
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 18
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function 18
Gene therapy using haematopoietic stem and progenitor cells 18
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 18
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity 18
Retrieval of vector integration sites from cell-free DNA 18
Hematopoietic stem-and progenitor-cell gene therapy for hurler syndrome 18
The EHA Research Roadmap: Hematopoietic Stem Cell Gene Therapy 18
A Case of Two Adult Brothers with Wiskott-Aldrich Syndrome, One Treated with Gene Therapy and One with HLA-Identical Hematopoietic Stem Cell Transplantation 18
Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series 18
Interleukin 7 production by bone marrow-derived stromal cells in HIV-1-infected patients during highly active antiretroviral therapy 17
A novel genomic inversion in Wiskott-Aldrich-associated autoinflammation 17
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 17
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 17
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 17
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 17
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients 17
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 17
Evidence of Treatment Benefits in Patients with Mucopolysaccharidosis Type I-Hurler in Long-term Follow-up Using a New Magnetic Resonance Imaging Scoring System 17
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) 16
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 16
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 16
A map of human circular RNAs in clinically relevant tissues 16
JAK3 mutations in Italian patients affected by SCID: New molecular aspects of a long-known gene 16
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 16
Third cranial nerve palsy in an 88-year-old man after SARS-CoV-2 mRNA vaccination: Change of injection site and type of vaccine resulted in an uneventful second dose with humoral immune response 16
A Prevalent CXCR3+ Phenotype of Circulating Follicular Helper T Cells Indicates Humoral Dysregulation in Children with Down Syndrome 16
An innovative platform approach for the development of ex-vivo gene therapies for the treatment of lysosomal storage diseases with skeletal involvement 16
Correction to: A Case of Two Adult Brothers with Wiskott‑Aldrich Syndrome, One Treated with Gene Therapy and One with HLA‑Identical Hematopoietic Stem Cell Transplantation (Journal of Clinical Immunology, (2022), 42, 2, (421-425), 10.1007/s10875-021-01157-6) 15
Control of human coagulation by recombinant serine proteases. Blood clotting is activated by recombinant factor XII deleted of five regulatory domains 15
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood 15
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 15
Twenty-Five Years of Gene Therapy for ADA-SCID: From Bubble Babies to an Approved Drug 15
Neutrophils drive type-I interferon production and autoantibodies in Wiskott-Aldrich syndrome 15
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 15
Leukocyte and Dried Blood Spot Arylsulfatase A Assay by Tandem Mass Spectrometry 15
Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency 15
Immunosuppressive therapy in childhood‐onset arrhythmogenic inflammatory cardiomyopathy 15
Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006) 15
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 15
Persistence of circulating T-follicular helper cells after rituximab is associated with relapse of IgG4-related disease 15
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress 14
Hematopoietic reconstitution dynamics of mobilized- and bone marrow-derived human hematopoietic stem cells after gene therapy 14
Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation 14
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation 14
Spectrotype of anti-gp120 antibodies remains stable during the course of HIV disease 14
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 14
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH) 14
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 14
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 14
Terapia genica e malattia ereditaria 14
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 14
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 14
Impaired X-CGD T cell compartment is gp91phox-NADPH oxidase independent 14
Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase δ syndrome: The European society for immunodeficiencies-activated phosphoinositide 3-kinase δ syndrome registry 14
LENTIVIRAL VECTOR TRANSDUCED CD34+CELLS FOR THE TREATMENT OF WISKOTT-ALDRICH SYNDROME 14
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 14
The Role of Conditioning in Hematopoietic Stem-Cell Gene Therapy 14
Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice 14
Consensus of the Italian Primary Immunodeficiency Network on transition management from pediatric to adult care in patients affected with childhood-onset inborn errors of immunity 14
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 14
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 14
Up to 10.5 Years of Follow-Up in 17 Subjects Treated with Hematopoietic Stem and Progenitor Cell Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome 13
Access to gene therapy for rare diseases when commercialization is not fit for purpose 13
Gene therapy in pediatrics 13
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 13
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 13
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement 13
Lentiviral vector gene therapy protects XCGD mice from acute Staphylococcus aureus pneumonia and inflammatory response 13
Totale 1.966
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Categoria #
all - tutte 57.325
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 57.325
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202052 21 0 0 4 0 1 0 4 0 22 0 0
2020/202162 5 2 1 0 14 18 17 0 4 1 0 0
2021/2022228 1 0 2 62 19 9 17 16 31 52 13 6
2022/20231.630 607 346 108 26 21 194 61 104 85 22 26 30
2023/20241.104 83 56 117 114 89 201 44 87 9 53 62 189
2024/2025499 499 0 0 0 0 0 0 0 0 0 0 0
Totale 3.677