IRIS
AIUTI, ALESSANDRO
 Distribuzione geografica
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Continente #
EU - Europa 1.277
NA - Nord America 1.134
AS - Asia 136
OC - Oceania 11
AF - Africa 10
Continente sconosciuto - Info sul continente non disponibili 3
SA - Sud America 1
Totale 2.572
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Nazione #
US - Stati Uniti d'America 1.125
SE - Svezia 802
IT - Italia 253
CN - Cina 61
FI - Finlandia 52
IE - Irlanda 49
DE - Germania 47
IN - India 33
GB - Regno Unito 25
SG - Singapore 15
FR - Francia 10
AU - Australia 9
NL - Olanda 8
RU - Federazione Russa 8
CA - Canada 7
ES - Italia 6
JP - Giappone 6
ET - Etiopia 5
KR - Corea 5
AT - Austria 4
TR - Turchia 4
BE - Belgio 3
DZ - Algeria 3
EU - Europa 3
IQ - Iraq 3
LV - Lettonia 3
BG - Bulgaria 2
HK - Hong Kong 2
ID - Indonesia 2
MX - Messico 2
MY - Malesia 2
NZ - Nuova Zelanda 2
PL - Polonia 2
BD - Bangladesh 1
BR - Brasile 1
CI - Costa d'Avorio 1
CZ - Repubblica Ceca 1
IR - Iran 1
MK - Macedonia 1
NG - Nigeria 1
TW - Taiwan 1
UA - Ucraina 1
Totale 2.572
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Città #
Lawrence 270
Princeton 270
Ashburn 129
New York 118
Milan 104
Shanghai 54
Helsinki 51
Dublin 47
Pune 23
Hanover 18
Rome 17
Washington 16
Seattle 15
Los Angeles 13
London 10
Perugia 7
Brisbane 6
Singapore 6
Aksum 5
Beijing 5
Cambridge 5
Livorno 5
Rockville 5
San Jose 5
Amsterdam 4
Brescia 4
Chevy Chase 4
Delhi 4
Michaelnbach 4
Philadelphia 4
Algiers 3
Andover 3
Barcelona 3
Bethesda 3
Borås 3
Cagliari 3
Castelseprio 3
Ercolano 3
Gijang-gun 3
Hillah 3
Loughton 3
Monza 3
Moorestown 3
Park City 3
Riga 3
Santa Clara 3
St Petersburg 3
Toronto 3
Verona 3
Athlone 2
Aurora 2
Belluno 2
Berlin 2
Bisceglie 2
Bristol 2
Brooklyn 2
Bursa 2
Campobasso 2
Casier 2
Cherry Hill 2
Chicago 2
Council Bluffs 2
Crema 2
Dayton 2
Düsseldorf 2
Elmendorf 2
Farmington 2
Gustavo Adolfo Madero 2
Hamilton 2
Hong Kong 2
Hyderabad 2
Kingston upon Thames 2
Kuala Lumpur 2
Langhirano 2
Las Vegas 2
Laurel 2
Limbiate 2
Madrid 2
Mountain View 2
Newtown 2
Palo Alto 2
Paris 2
Plovdiv 2
Reggio Emilia 2
Roslindale 2
Ruislip 2
Salerno 2
Sant'Andrea Bagni 2
Schaarbeek 2
Schiphol 2
Sydney 2
Tokyo 2
Torino 2
Varese 2
Venice 2
Vittuone 2
Warsaw 2
Wayland 2
Wembley 2
Winnipeg 2
Totale 1.387
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 170
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 54
Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency 43
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies 25
Membrane expression of HLA-Cw4 free chains in activated T cells of transgenic mice 23
Wiskott–Aldrich syndrome: Oral findings and microbiota in children and review of the literature 23
Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency 23
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 22
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19 20
Linee Guida per la diagnosi e terapia dell’Immunodeficienza Comune Variabile 20
Intrabone hematopoietic stem cell gene therapy for adult and pediatric patients affected by transfusion-dependent ß-thalassemia 20
ALPS-Like Phenotype Caused by ADA2 Deficiency Rescued by Allogeneic Hematopoietic Stem Cell Transplantation 20
Corrigendum: Targeted NGS Platforms for Genetic Screening and Gene Discovery in Primary Immunodeficiencies 20
A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection 20
Lentiviral haematopoietic stem-cell gene therapy for early-onset metachromatic leukodystrophy: long-term results from a non-randomised, open-label, phase 1/2 trial and expanded access 20
Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity 20
Metachromatic leukodystrophy: A single-center longitudinal study of 45 patients 19
Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis 19
B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients 18
Reduced PD-1 expression on circulating follicular and conventional FOXP3+ Treg cells in children with new onset type 1 diabetes and autoantibody-positive at-risk children 18
Emapalumab treatment in an ADA-SCID patient with refractory hemophagocytic lymphohistiocytosis-related graft failure and disseminated BCGitis 17
Pioglitazone as a novel therapeutic approach in chronic granulomatous disease 17
Mild SARS-CoV-2 Infection After Gene Therapy in a Child With Wiskott-Aldrich Syndrome: A Case Report 17
Mesenchymal stromal cells improve the transplantation outcome of CRISPR-Cas9 gene-edited human HSPCs. 16
Interleukin 7 production by bone marrow-derived stromal cells in HIV-1-infected patients during highly active antiretroviral therapy 16
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 16
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 16
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 16
A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function 16
Bone marrow harvesting from paediatric patients undergoing haematopoietic stem cell gene therapy 16
The EHA Research Roadmap: Hematopoietic Stem Cell Gene Therapy 16
A Case of Two Adult Brothers with Wiskott-Aldrich Syndrome, One Treated with Gene Therapy and One with HLA-Identical Hematopoietic Stem Cell Transplantation 16
Control of human coagulation by recombinant serine proteases. Blood clotting is activated by recombinant factor XII deleted of five regulatory domains 15
A novel genomic inversion in Wiskott-Aldrich-associated autoinflammation 15
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 15
JAK3 mutations in Italian patients affected by SCID: New molecular aspects of a long-known gene 15
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 15
Bone marrow stromal cells from β-thalassemia patients have impaired hematopoietic supportive capacity 15
Retrieval of vector integration sites from cell-free DNA 15
Hematopoietic stem-and progenitor-cell gene therapy for hurler syndrome 15
Peripheral blood stem and progenitor cell collection in pediatric candidates for ex vivo gene therapy: a 10-year series 15
A Novel Assay in Whole Blood Demonstrates Restoration of Mitochondrial Activity in Phagocytes After Successful HSCT in Hyperinflamed X-Linked Chronic Granulomatous Disease 14
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 14
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 14
Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients 14
Gene therapy using haematopoietic stem and progenitor cells 14
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 14
Evidence of Treatment Benefits in Patients with Mucopolysaccharidosis Type I-Hurler in Long-term Follow-up Using a New Magnetic Resonance Imaging Scoring System 14
Persistence of circulating T-follicular helper cells after rituximab is associated with relapse of IgG4-related disease 14
Identification of distinct elements of the stromal microenvironment that control human hematopoietic stem/progenitor cell growth and differentiation 13
Spectrotype of anti-gp120 antibodies remains stable during the course of HIV disease 13
AQP8 transports NOX2-generated H2O2 across the plasma membrane to promote signaling in B cells 13
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1) 13
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 13
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate 13
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood 13
Twenty-Five Years of Gene Therapy for ADA-SCID: From Bubble Babies to an Approved Drug 13
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 13
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency 13
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 13
Urogenital Abnormalities in Adenosine Deaminase Deficiency 13
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 13
Lentiviral correction of enzymatic activity restrains macrophage inflammation in adenosine deaminase 2 deficiency 13
A Prevalent CXCR3+ Phenotype of Circulating Follicular Helper T Cells Indicates Humoral Dysregulation in Children with Down Syndrome 13
Up to 10.5 Years of Follow-Up in 17 Subjects Treated with Hematopoietic Stem and Progenitor Cell Lentiviral Gene Therapy for Wiskott-Aldrich Syndrome 12
Correction to: A Case of Two Adult Brothers with Wiskott‑Aldrich Syndrome, One Treated with Gene Therapy and One with HLA‑Identical Hematopoietic Stem Cell Transplantation (Journal of Clinical Immunology, (2022), 42, 2, (421-425), 10.1007/s10875-021-01157-6) 12
Wiskott-Aldrich syndrome protein regulates lipid raft dynamics during immunological synapse formation 12
Gene therapy in pediatrics 12
Hematopoietic support and cytokine expression of murine-stable hepatocyte cell lines (MMH) 12
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 12
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 12
A map of human circular RNAs in clinically relevant tissues 12
Neutrophils drive type-I interferon production and autoantibodies in Wiskott-Aldrich syndrome 12
Disease evolution and response to rapamycin in activated phosphoinositide 3-kinase δ syndrome: The European society for immunodeficiencies-activated phosphoinositide 3-kinase δ syndrome registry 12
Good Laboratory Practice Preclinical Safety Studies for GSK2696273 (MLV Vector-Based Ex Vivo Gene Therapy for Adenosine Deaminase Deficiency Severe Combined Immunodeficiency) in NSG Mice 12
Immunosuppressive therapy in childhood‐onset arrhythmogenic inflammatory cardiomyopathy 12
Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006) 12
X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life-threatening COVID-19 12
Third cranial nerve palsy in an 88-year-old man after SARS-CoV-2 mRNA vaccination: Change of injection site and type of vaccine resulted in an uneventful second dose with humoral immune response 12
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress 11
Expression of CXCR4, the receptor for stromal cell-derived factor-1 on fetal and adult human lympho-hematopoietic progenitors 11
Lack of evidence for a superantigen in lymphocytes from HIV-discordant monozygotic twins 11
Cell-surface marking of CD(34+)-restricted phenotypes of human hematopoietic progenitor cells by retrovirus-mediated gene transfer 11
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 11
Clinical applications of gene therapy for primary immunodeficiencies 11
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 11
Early-onset monocyte-B-natural killer-dendritic cells’ deficiency successfully treated with hematopoietic stem cell transplantation 11
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 11
Clonal analyses of retroviral vector integrations in ADA-SCID patients treated with stem cell gene therapy 11
Human CD34(+) cells express CXCR4 and its ligand stromal cell-derived factor-1. Implications for infection by T-cell tropic human immunodeficiency virus 11
Impaired X-CGD T cell compartment is gp91phox-NADPH oxidase independent 11
Circulating follicular helper and follicular regulatory T cells are severely compromised in human CD40 deficiency: A case report 11
LENTIVIRAL VECTOR TRANSDUCED CD34+CELLS FOR THE TREATMENT OF WISKOTT-ALDRICH SYNDROME 11
Penalized inference of the hematopoietic cell differentiation network via high-dimensional clonal tracking 11
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 11
First case of patient with two homozygous mutations in MYD88 and CARD9 genes presenting with pyogenic bacterial infections, elevated IgE, and persistent EBV viremia 11
The Role of Conditioning in Hematopoietic Stem-Cell Gene Therapy 11
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths 11
T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency 11
Induction of CD4+ T cell depletion in mice doubly transgenic for HIV gp120 and human CD4 10
Totale 1.664
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Categoria #
all - tutte 47.551
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 47.551
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/20191 0 0 0 0 0 0 0 0 0 0 1 0
2019/202052 21 0 0 4 0 1 0 4 0 22 0 0
2020/202162 5 2 1 0 14 18 17 0 4 1 0 0
2021/2022228 1 0 2 62 19 9 17 16 31 52 13 6
2022/20231.630 607 346 108 26 21 194 61 104 85 22 26 30
2023/2024855 83 56 117 114 89 201 44 87 9 53 2 0
Totale 2.929