IRIS
GUIDOTTI, LUCA
 Distribuzione geografica
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Continente #
EU - Europa 3.662
AS - Asia 3.281
NA - Nord America 1.985
SA - Sud America 772
AF - Africa 79
OC - Oceania 9
Continente sconosciuto - Info sul continente non disponibili 1
Totale 9.789
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Nazione #
RU - Federazione Russa 2.206
US - Stati Uniti d'America 1.878
SG - Singapore 1.208
CN - Cina 1.070
BR - Brasile 619
SE - Svezia 547
HK - Hong Kong 432
VN - Vietnam 310
IT - Italia 281
FR - Francia 160
DE - Germania 142
GB - Regno Unito 78
AR - Argentina 66
IN - India 54
CA - Canada 46
FI - Finlandia 46
AT - Austria 41
MX - Messico 40
PL - Polonia 40
ID - Indonesia 39
BD - Bangladesh 29
IQ - Iraq 29
EC - Ecuador 28
NL - Olanda 27
CO - Colombia 24
ZA - Sudafrica 24
IE - Irlanda 17
TR - Turchia 17
ES - Italia 16
PK - Pakistan 14
GH - Ghana 13
UA - Ucraina 11
PY - Paraguay 10
AU - Australia 9
CL - Cile 9
JP - Giappone 9
SA - Arabia Saudita 9
CH - Svizzera 8
MA - Marocco 8
AE - Emirati Arabi Uniti 7
PH - Filippine 7
RO - Romania 7
UZ - Uzbekistan 7
VE - Venezuela 7
BE - Belgio 6
AL - Albania 5
DZ - Algeria 5
IR - Iran 5
TW - Taiwan 5
BO - Bolivia 4
CZ - Repubblica Ceca 4
EG - Egitto 4
KE - Kenya 4
LB - Libano 4
LT - Lituania 4
RS - Serbia 4
CR - Costa Rica 3
ET - Etiopia 3
IL - Israele 3
JM - Giamaica 3
KZ - Kazakistan 3
MK - Macedonia 3
MY - Malesia 3
TH - Thailandia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
UY - Uruguay 3
AO - Angola 2
CG - Congo 2
DO - Repubblica Dominicana 2
HN - Honduras 2
KN - Saint Kitts e Nevis 2
KR - Corea 2
OM - Oman 2
PA - Panama 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
SZ - Regno dello Swaziland 2
YE - Yemen 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
CI - Costa d'Avorio 1
DK - Danimarca 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GY - Guiana 1
JO - Giordania 1
KH - Cambogia 1
LV - Lettonia 1
LY - Libia 1
NG - Nigeria 1
NO - Norvegia 1
Totale 9.782
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Città #
Singapore 489
Moscow 433
Hong Kong 424
Ashburn 362
Dallas 234
Shanghai 170
San Jose 167
Hefei 158
Lawrence 142
Princeton 142
Lauterbourg 141
Beijing 130
Ho Chi Minh City 117
Milan 99
Hanoi 69
New York 62
São Paulo 59
The Dalles 59
Los Angeles 58
Nuremberg 40
Helsinki 36
Warsaw 35
Boardman 32
Orem 29
Rome 28
Denver 26
Munich 23
Santa Clara 21
Belo Horizonte 20
Stockholm 19
Vienna 19
Cesano Boscone 17
Dublin 17
Montreal 17
Amsterdam 16
Atlanta 15
London 15
Rio de Janeiro 15
Houston 14
Brooklyn 13
Chennai 13
Manchester 13
São José dos Campos 13
Accra 12
Council Bluffs 12
Florence 12
Guangzhou 12
Biên Hòa 11
Johannesburg 11
Poplar 11
Shenzhen 11
Brasília 10
Frankfurt am Main 10
Phoenix 10
Porto Alegre 10
Pune 10
Seattle 10
Tianjin 10
Curitiba 9
Da Nang 9
Haiphong 9
Mexico City 9
Quito 9
Boston 8
Jiaxing 8
Pelotas 8
Querétaro 8
Salvador 8
Thái Bình 8
Toronto 8
Xi'an 8
Erbil 7
Ha Long 7
Meda 7
Mumbai 7
San Francisco 7
Tashkent 7
Tokyo 7
Baghdad 6
Barnet 6
Campinas 6
Fortaleza 6
Heidelberg 6
Mainz 6
Manaus 6
Thái Nguyên 6
Wuxi 6
Bogotá 5
Buenos Aires 5
Chicago 5
Columbus 5
Goiânia 5
Guarulhos 5
Guayaquil 5
La Plata 5
Lappeenranta 5
New Delhi 5
Riyadh 5
Uberlândia 5
Ancona 4
Totale 4.459
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Nome #
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion 164
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models 159
CD4+T cells license Kupffer cells to produce IL-27 and reverse the CD8+T cell dysfunction induced by hepatocellular priming 157
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination 153
Immunobiology and pathogenesis of hepatitis B virus infection 147
Therapeutic potential of co-signaling receptor modulation in hepatitis B 140
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming 131
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. 121
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators 117
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming 114
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 107
Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability 106
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses 105
Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens 102
Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets 101
Bone marrow as an alternative site for islet transplantation 100
Extracellular HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV pathogenesis 100
Inflammatory monocytes hinder antiviral B cell responses 99
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma 98
Effector CD8+T cell-derived interleukin-10 enhances acute liver immunopathology 97
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection 97
Immunosurveillance of the liver by intravascular effector CD8+ T cells 96
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans 96
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming 93
Bone marrow as an alternative site for islet transplantation 91
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus 91
Altered helper T lymphocyte (HTL) function associated with chronic HBV infection and its role in response to therapeutic vaccination in humans 90
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen 89
A two hit model of CTL killing in vivo 88
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses 87
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier 85
Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice 85
Role of CCL2/MCP-1 in islet transplantation 83
Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice 81
Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 80
Immunological insights in the treatment of chronic hepatitis B 80
A global scientific strategy to cure hepatitis B 79
Activated intrahepatic antigen presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 74
Platelets mediate cytotoxic T lymphocyte-induced liver damage 73
In vivo flow mapping in complex vessel networks by single image correlation 72
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes 72
Preclinical assessment of capsid assembly modulators (CAMs) of varying potency revealed a novel class of picomolar-acting CAMs inducing neither significant HBcAg cytoplasmic retention nor adverse interactions with HBcAg-specific adaptive immunity 71
Analysis of a successful immune response against HBV 70
IFN gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment 70
Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4(+) T Cell Help 69
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis 67
Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice 66
Inhibitors of hepatitis B virus 66
Pathogenesis of hepatitis B virus in transgenic mice 64
Protective and Pathogenic T Cell Responses to Virus Infections 64
MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs 63
Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes 63
Platelets mediate cytotoxic T lymphocyte-induced liver damage 62
Platelets mediate CTL-induced immunopathology in the liver 59
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation 59
Is it time to recommend low-dose aspirin treatment for the prevention of hepatocellular carcinoma? 59
Cyclic inhibitors of hepatitis B virus 59
Tricyclic inhibitors of hepatitis B virus 59
Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells 58
The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver 58
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus 57
CTL-induced liver disease requires co-stimulation of both the Fas ligand- and perforin-activated death pathways 57
T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses 56
Pathogenetic and antiviral immune responses against hepatitis B virus 56
HBV pathogenesis in animal models: Recent advances on the role of platelets 56
The optimization of helper T lymphocyte (HTL) function in vaccine development 56
Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes 56
Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice 56
Cytokine-mediated control of viral infections 56
Effector CD8 T cell trafficking within the liver 56
T helper-1 lymphocytes mediate liver disease in hepatitis B virus transgenic mice 55
CTL access to tissue antigen is restricted in-vivo 55
Editorial overview: Viral pathogenesis 55
The transgenic mouse model of hepatitis B virus infection 55
HBV Immunopathogenesis 55
A rapid and robust luciferase-based reporter system to assess SARS-CoV-2 protease activity 54
In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance 54
Cytotoxic T-lymphocytes can clear hepatitis-B virus from the hepatocyte without killing the cell 54
Mouse models of hepatitis B virus pathogenesis 54
Class-I restricted cytotoxic T-lymphocytes are directly cytopathic for their target-cells in-vivo 54
Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy 53
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes 53
Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich Syndrome patients 53
Liver gene expression associated with the inhibition of HBV replication or transcription 52
High-level hepatitis-B virus-replication in transgenic mice 52
Mechanisms of class-I restricted immunopathology - a transgenic mouse model of fulminant-hepatitis 52
Kupffer cells reduce liver immunopathology 52
Hepatitis C virus core and E2 protein expression in transgenic mice 52
Host-virus interactions during malaria infection in hepatitis B virus transgenic mice 52
Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy 52
Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis 51
The hepatitis B virus X protein transactivates viral core gene expression in vivo 51
Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice 50
Hepatitis B virus RNA-binding proteins associated with cytokine-induced clearance of viral RNA from the liver of transgenic mice 50
Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus 49
TIE2-expressing monocytes regulate revascularisation of the ischaemic limb 49
Update of the statements on biology and clinical impact of occult hepatitis B virus infection 49
Cytotoxic T-lymphocyte mediated regulation of hepatitis-B virus gene-expression in-vivo 48
Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site 48
Hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice 48
Totale 7.529
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Categoria #
all - tutte 60.292
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 60.292
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20212 0 0 0 0 0 0 0 0 0 2 0 0
2021/2022121 0 0 0 57 2 0 6 3 5 7 5 36
2022/2023846 302 200 62 2 13 118 21 78 31 1 4 14
2023/2024419 22 16 59 114 29 37 13 29 4 10 31 55
2024/20252.003 264 20 15 59 85 161 261 263 348 194 154 179
2025/20266.434 434 433 469 1.049 528 218 521 521 1.999 262 0 0
Totale 9.929