IRIS
GUIDOTTI, LUCA
 Distribuzione geografica
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Continente #
EU - Europa 3.960
AS - Asia 3.468
NA - Nord America 3.349
SA - Sud America 786
Continente sconosciuto - Info sul continente non disponibili 144
AF - Africa 80
OC - Oceania 9
Totale 11.796
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Nazione #
US - Stati Uniti d'America 3.122
RU - Federazione Russa 2.206
SG - Singapore 1.237
CN - Cina 1.121
BR - Brasile 623
SE - Svezia 547
IT - Italia 540
HK - Hong Kong 440
VN - Vietnam 320
FR - Francia 162
DE - Germania 147
BD - Bangladesh 100
GB - Regno Unito 96
CA - Canada 92
AR - Argentina 67
IN - India 55
FI - Finlandia 46
ID - Indonesia 45
MX - Messico 44
AT - Austria 41
PL - Polonia 40
EC - Ecuador 33
NL - Olanda 32
IQ - Iraq 29
CO - Colombia 26
ZA - Sudafrica 24
CR - Costa Rica 19
ES - Italia 18
IE - Irlanda 17
JM - Giamaica 17
TR - Turchia 17
PK - Pakistan 14
GH - Ghana 13
HN - Honduras 11
JP - Giappone 11
RO - Romania 11
UA - Ucraina 11
PY - Paraguay 10
AU - Australia 9
CL - Cile 9
NI - Nicaragua 9
SA - Arabia Saudita 9
TT - Trinidad e Tobago 9
VE - Venezuela 9
CH - Svizzera 8
MA - Marocco 8
AE - Emirati Arabi Uniti 7
PH - Filippine 7
UZ - Uzbekistan 7
BE - Belgio 6
MY - Malesia 6
TW - Taiwan 6
AL - Albania 5
CZ - Repubblica Ceca 5
DZ - Algeria 5
EG - Egitto 5
IR - Iran 5
SV - El Salvador 5
BO - Bolivia 4
KE - Kenya 4
LB - Libano 4
LT - Lituania 4
RS - Serbia 4
ET - Etiopia 3
GP - Guadalupe 3
IL - Israele 3
KR - Corea 3
KZ - Kazakistan 3
MK - Macedonia 3
NP - Nepal 3
PR - Porto Rico 3
TH - Thailandia 3
TN - Tunisia 3
UY - Uruguay 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
BS - Bahamas 2
CG - Congo 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
GT - Guatemala 2
KH - Cambogia 2
KN - Saint Kitts e Nevis 2
OM - Oman 2
PA - Panama 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
SZ - Regno dello Swaziland 2
YE - Yemen 2
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BW - Botswana 1
BZ - Belize 1
CD - Congo 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
GA - Gabon 1
Totale 11.638
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Città #
Ashburn 576
Singapore 504
Moscow 433
Hong Kong 432
San Jose 341
Dallas 245
Milan 192
Council Bluffs 183
Shanghai 173
Hefei 158
Princeton 143
Lawrence 142
Beijing 141
Lauterbourg 141
Ho Chi Minh City 118
Los Angeles 75
Hanoi 70
New York 70
The Dalles 63
São Paulo 59
Phoenix 48
Santa Clara 47
Nuremberg 40
Helsinki 36
Rome 36
Warsaw 35
Boardman 34
Orem 32
Denver 30
Miano 30
Houston 23
Montreal 23
Munich 23
Brooklyn 22
Atlanta 21
Belo Horizonte 20
Stockholm 19
Vienna 19
Florence 18
Cesano Boscone 17
Dublin 17
London 17
Amsterdam 16
Rio de Janeiro 15
Kingston 14
Manchester 14
San José 14
Chennai 13
Da Nang 13
Omaha 13
São José dos Campos 13
Toronto 13
Accra 12
Chicago 12
Guangzhou 12
Biên Hòa 11
Frankfurt am Main 11
Johannesburg 11
Mexico City 11
Poplar 11
Porto Alegre 11
Quito 11
Seattle 11
Shenzhen 11
Brasília 10
Naples 10
Pune 10
San Francisco 10
Tianjin 10
Calgary 9
Curitiba 9
Haiphong 9
Boston 8
Jiaxing 8
Managua 8
Pelotas 8
Querétaro 8
Salvador 8
Thái Bình 8
Xi'an 8
Erbil 7
Ha Long 7
Meda 7
Miami 7
Mumbai 7
Tashkent 7
Tokyo 7
Baghdad 6
Barnet 6
Bogotá 6
Buenos Aires 6
Campinas 6
Columbus 6
Dhaka 6
Fortaleza 6
Guayaquil 6
Heidelberg 6
Kuala Lumpur 6
La Plata 6
Mainz 6
Totale 5.407
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Nome #
Therapeutic potential of co-signaling receptor modulation in hepatitis B 251
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models 185
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion 183
CD4+T cells license Kupffer cells to produce IL-27 and reverse the CD8+T cell dysfunction induced by hepatocellular priming 177
Immunobiology and pathogenesis of hepatitis B virus infection 175
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination 173
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators 157
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming 146
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses 137
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. 137
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 128
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming 126
Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability 124
Bone marrow as an alternative site for islet transplantation 120
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming 118
Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens 118
Immunosurveillance of the liver by intravascular effector CD8+ T cells 116
Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets 114
Inflammatory monocytes hinder antiviral B cell responses 114
Extracellular HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV pathogenesis 113
Effector CD8+T cell-derived interleukin-10 enhances acute liver immunopathology 110
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma 110
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection 110
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses 106
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans 105
T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses 104
Bone marrow as an alternative site for islet transplantation 101
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus 99
Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice 99
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier 97
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen 97
Altered helper T lymphocyte (HTL) function associated with chronic HBV infection and its role in response to therapeutic vaccination in humans 97
A two hit model of CTL killing in vivo 95
Immunological insights in the treatment of chronic hepatitis B 95
Role of CCL2/MCP-1 in islet transplantation 92
A global scientific strategy to cure hepatitis B 92
Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 91
Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice 90
Activated intrahepatic antigen presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 85
In vivo flow mapping in complex vessel networks by single image correlation 84
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes 83
Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells 82
Platelets mediate cytotoxic T lymphocyte-induced liver damage 82
Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4(+) T Cell Help 81
Preclinical assessment of capsid assembly modulators (CAMs) of varying potency revealed a novel class of picomolar-acting CAMs inducing neither significant HBcAg cytoplasmic retention nor adverse interactions with HBcAg-specific adaptive immunity 80
The transgenic mouse model of hepatitis B virus infection 78
IFN gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment 78
Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes 78
Scientific and medical evidence informing expansion of hepatitis B treatment guidelines 77
MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs 76
Analysis of a successful immune response against HBV 76
A rapid and robust luciferase-based reporter system to assess SARS-CoV-2 protease activity 74
Protective and Pathogenic T Cell Responses to Virus Infections 74
Inhibitors of hepatitis B virus 74
Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice 73
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis 73
Platelets mediate cytotoxic T lymphocyte-induced liver damage 73
In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance 71
The optimization of helper T lymphocyte (HTL) function in vaccine development 70
Pathogenesis of hepatitis B virus in transgenic mice 69
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation 69
Tricyclic inhibitors of hepatitis B virus 68
CTL access to tissue antigen is restricted in-vivo 67
Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy 67
Cyclic inhibitors of hepatitis B virus 67
Cytokine-mediated control of viral infections 66
CTL-induced liver disease requires co-stimulation of both the Fas ligand- and perforin-activated death pathways 66
The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver 66
Effector CD8 T cell trafficking within the liver 66
Update of the statements on biology and clinical impact of occult hepatitis B virus infection 66
Is it time to recommend low-dose aspirin treatment for the prevention of hepatocellular carcinoma? 66
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus 65
Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus 65
Platelets mediate CTL-induced immunopathology in the liver 65
Mouse models of hepatitis B virus pathogenesis 65
T helper-1 lymphocytes mediate liver disease in hepatitis B virus transgenic mice 64
Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes 64
HBV pathogenesis in animal models: Recent advances on the role of platelets 63
Mechanisms of class-I restricted immunopathology - a transgenic mouse model of fulminant-hepatitis 63
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes 63
Editorial overview: Viral pathogenesis 63
Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy 62
Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice 62
High-level hepatitis-B virus-replication in transgenic mice 61
On the role of platelets in the pathogenesis of viral hepatitis 61
Kupffer cells reduce liver immunopathology 61
HBV Immunopathogenesis 61
Class-I restricted cytotoxic T-lymphocytes are directly cytopathic for their target-cells in-vivo 61
Liver gene expression associated with the inhibition of HBV replication or transcription 60
Pathogenetic and antiviral immune responses against hepatitis B virus 60
Host-virus interactions during malaria infection in hepatitis B virus transgenic mice 60
Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich Syndrome patients 60
Hepatitis C virus core and E2 protein expression in transgenic mice 59
The hepatitis B virus X protein transactivates viral core gene expression in vivo 59
TIE2-expressing monocytes regulate revascularisation of the ischaemic limb 59
Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis 58
Treatment with HMGB1 inhibitors diminishes CTL-induced liver disease in HBV transgenic mice 57
Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis 57
Cytotoxic T-lymphocytes can clear hepatitis-B virus from the hepatocyte without killing the cell 57
Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice 57
Totale 8.899
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Categoria #
all - tutte 72.536
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 72.536
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022121 0 0 0 57 2 0 6 3 5 7 5 36
2022/2023846 302 200 62 2 13 118 21 78 31 1 4 14
2023/2024419 22 16 59 114 29 37 13 29 4 10 31 55
2024/20252.003 264 20 15 59 85 161 261 263 348 194 154 179
2025/20266.825 434 433 469 1.049 528 218 521 521 1.999 343 218 92
2026/20271.476 162 353 375 586 0 0 0 0 0 0 0 0
Totale 11.796