GUIDOTTI, LUCA
 Distribuzione geografica
Continente #
EU - Europa 3.738
AS - Asia 3.455
NA - Nord America 2.550
SA - Sud America 777
Continente sconosciuto - Info sul continente non disponibili 143
AF - Africa 79
OC - Oceania 9
Totale 10.751
Nazione #
US - Stati Uniti d'America 2.401
RU - Federazione Russa 2.206
SG - Singapore 1.234
CN - Cina 1.116
BR - Brasile 620
SE - Svezia 547
HK - Hong Kong 440
IT - Italia 340
VN - Vietnam 319
FR - Francia 161
DE - Germania 143
BD - Bangladesh 100
GB - Regno Unito 84
AR - Argentina 67
CA - Canada 59
IN - India 55
FI - Finlandia 46
ID - Indonesia 43
MX - Messico 43
AT - Austria 41
PL - Polonia 40
NL - Olanda 32
EC - Ecuador 29
IQ - Iraq 29
CO - Colombia 25
ZA - Sudafrica 24
ES - Italia 18
IE - Irlanda 17
TR - Turchia 17
PK - Pakistan 14
GH - Ghana 13
CR - Costa Rica 11
UA - Ucraina 11
JP - Giappone 10
PY - Paraguay 10
AU - Australia 9
CL - Cile 9
HN - Honduras 9
SA - Arabia Saudita 9
CH - Svizzera 8
MA - Marocco 8
VE - Venezuela 8
AE - Emirati Arabi Uniti 7
JM - Giamaica 7
PH - Filippine 7
RO - Romania 7
UZ - Uzbekistan 7
BE - Belgio 6
MY - Malesia 6
TW - Taiwan 6
AL - Albania 5
CZ - Repubblica Ceca 5
DZ - Algeria 5
IR - Iran 5
BO - Bolivia 4
EG - Egitto 4
KE - Kenya 4
LB - Libano 4
LT - Lituania 4
RS - Serbia 4
ET - Etiopia 3
IL - Israele 3
KZ - Kazakistan 3
MK - Macedonia 3
NI - Nicaragua 3
NP - Nepal 3
TH - Thailandia 3
TN - Tunisia 3
TT - Trinidad e Tobago 3
UY - Uruguay 3
AO - Angola 2
BA - Bosnia-Erzegovina 2
CG - Congo 2
DO - Repubblica Dominicana 2
KH - Cambogia 2
KN - Saint Kitts e Nevis 2
KR - Corea 2
OM - Oman 2
PA - Panama 2
PR - Porto Rico 2
PT - Portogallo 2
SK - Slovacchia (Repubblica Slovacca) 2
SY - Repubblica araba siriana 2
SZ - Regno dello Swaziland 2
YE - Yemen 2
AZ - Azerbaigian 1
BB - Barbados 1
BG - Bulgaria 1
BH - Bahrain 1
BS - Bahamas 1
BW - Botswana 1
CD - Congo 1
CI - Costa d'Avorio 1
CW - ???statistics.table.value.countryCode.CW??? 1
DK - Danimarca 1
GA - Gabon 1
GD - Grenada 1
GE - Georgia 1
GY - Guiana 1
JO - Giordania 1
Totale 10.597
Città #
Singapore 503
Moscow 433
Hong Kong 432
Ashburn 392
Dallas 241
San Jose 241
Council Bluffs 179
Shanghai 173
Hefei 158
Princeton 143
Lawrence 142
Lauterbourg 141
Beijing 139
Ho Chi Minh City 118
Milan 104
Hanoi 70
Los Angeles 68
New York 68
The Dalles 62
São Paulo 59
Santa Clara 41
Nuremberg 40
Helsinki 36
Warsaw 35
Boardman 34
Rome 33
Orem 32
Denver 29
Munich 23
Belo Horizonte 20
Houston 20
Montreal 19
Stockholm 19
Vienna 19
Atlanta 18
Florence 18
Cesano Boscone 17
Dublin 17
London 17
Amsterdam 16
Brooklyn 15
Phoenix 15
Rio de Janeiro 15
Chennai 13
Da Nang 13
Manchester 13
Omaha 13
São José dos Campos 13
Accra 12
Guangzhou 12
Biên Hòa 11
Frankfurt am Main 11
Johannesburg 11
Mexico City 11
Poplar 11
Seattle 11
Shenzhen 11
Brasília 10
Porto Alegre 10
Pune 10
Tianjin 10
Chicago 9
Curitiba 9
Haiphong 9
Quito 9
San Francisco 9
Toronto 9
Boston 8
Jiaxing 8
Pelotas 8
Querétaro 8
Salvador 8
San José 8
Thái Bình 8
Xi'an 8
Erbil 7
Ha Long 7
Meda 7
Mumbai 7
Tashkent 7
Tokyo 7
Baghdad 6
Barnet 6
Buenos Aires 6
Campinas 6
Columbus 6
Dhaka 6
Fortaleza 6
Guayaquil 6
Heidelberg 6
Kingston 6
Kuala Lumpur 6
La Plata 6
Mainz 6
Manaus 6
Naples 6
Thái Nguyên 6
Wuxi 6
Bogotá 5
Calgary 5
Totale 4.892
Nome #
Therapeutic potential of co-signaling receptor modulation in hepatitis B 208
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models 174
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion 168
CD4+T cells license Kupffer cells to produce IL-27 and reverse the CD8+T cell dysfunction induced by hepatocellular priming 167
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination 167
Immunobiology and pathogenesis of hepatitis B virus infection 160
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators 150
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming 140
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. 133
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses 128
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming 121
Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability 114
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 112
Bone marrow as an alternative site for islet transplantation 111
Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens 109
Extracellular HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV pathogenesis 108
Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets 107
Effector CD8+T cell-derived interleukin-10 enhances acute liver immunopathology 106
Immunosurveillance of the liver by intravascular effector CD8+ T cells 106
Inflammatory monocytes hinder antiviral B cell responses 105
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection 105
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma 103
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses 101
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming 100
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans 98
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus 95
T cell-derived IFN-γ Suppresses T Follicular Helper Cell Differentiation and Antibody Responses 94
Bone marrow as an alternative site for islet transplantation 94
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen 92
Altered helper T lymphocyte (HTL) function associated with chronic HBV infection and its role in response to therapeutic vaccination in humans 92
A two hit model of CTL killing in vivo 91
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier 89
Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice 88
Immunological insights in the treatment of chronic hepatitis B 88
Role of CCL2/MCP-1 in islet transplantation 87
Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice 85
Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 84
A global scientific strategy to cure hepatitis B 81
Activated intrahepatic antigen presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 80
In vivo flow mapping in complex vessel networks by single image correlation 79
Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4(+) T Cell Help 77
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes 76
Preclinical assessment of capsid assembly modulators (CAMs) of varying potency revealed a novel class of picomolar-acting CAMs inducing neither significant HBcAg cytoplasmic retention nor adverse interactions with HBcAg-specific adaptive immunity 76
Platelets mediate cytotoxic T lymphocyte-induced liver damage 75
Preclinical evaluation of therapeutic vaccines for chronic hepatitis B that stimulate antiviral activities of T cells and NKT cells 73
IFN gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment 73
Analysis of a successful immune response against HBV 72
Protective and Pathogenic T Cell Responses to Virus Infections 71
MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs 70
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis 69
Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice 68
Inhibitors of hepatitis B virus 68
Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes 67
Pathogenesis of hepatitis B virus in transgenic mice 66
A rapid and robust luciferase-based reporter system to assess SARS-CoV-2 protease activity 65
Platelets mediate cytotoxic T lymphocyte-induced liver damage 65
Scientific and medical evidence informing expansion of hepatitis B treatment guidelines 64
In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance 63
Is it time to recommend low-dose aspirin treatment for the prevention of hepatocellular carcinoma? 62
Tricyclic inhibitors of hepatitis B virus 62
Platelets mediate CTL-induced immunopathology in the liver 61
The optimization of helper T lymphocyte (HTL) function in vaccine development 61
The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver 61
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation 61
Cyclic inhibitors of hepatitis B virus 61
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus 60
T helper-1 lymphocytes mediate liver disease in hepatitis B virus transgenic mice 60
CTL-induced liver disease requires co-stimulation of both the Fas ligand- and perforin-activated death pathways 60
Effector CD8 T cell trafficking within the liver 60
Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes 59
CTL access to tissue antigen is restricted in-vivo 59
Cytokine-mediated control of viral infections 59
The transgenic mouse model of hepatitis B virus infection 59
HBV pathogenesis in animal models: Recent advances on the role of platelets 58
Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice 58
Mouse models of hepatitis B virus pathogenesis 58
Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy 58
HBV Immunopathogenesis 58
Pathogenetic and antiviral immune responses against hepatitis B virus 57
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes 57
Editorial overview: Viral pathogenesis 57
Liver gene expression associated with the inhibition of HBV replication or transcription 56
High-level hepatitis-B virus-replication in transgenic mice 56
Mechanisms of class-I restricted immunopathology - a transgenic mouse model of fulminant-hepatitis 56
Class-I restricted cytotoxic T-lymphocytes are directly cytopathic for their target-cells in-vivo 56
Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy 55
Kupffer cells reduce liver immunopathology 55
Hepatitis C virus core and E2 protein expression in transgenic mice 55
Cytotoxic T-lymphocytes can clear hepatitis-B virus from the hepatocyte without killing the cell 55
TIE2-expressing monocytes regulate revascularisation of the ischaemic limb 55
Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich Syndrome patients 55
Update of the statements on biology and clinical impact of occult hepatitis B virus infection 54
Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus 53
Host-virus interactions during malaria infection in hepatitis B virus transgenic mice 53
On the role of platelets in the pathogenesis of viral hepatitis 52
Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis 52
Hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice 52
The hepatitis B virus X protein transactivates viral core gene expression in vivo 52
Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice 52
Tumor-targeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis 51
Totale 8.169
Categoria #
all - tutte 67.982
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 67.982


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022121 0 0 0 57 2 0 6 3 5 7 5 36
2022/2023846 302 200 62 2 13 118 21 78 31 1 4 14
2023/2024419 22 16 59 114 29 37 13 29 4 10 31 55
2024/20252.003 264 20 15 59 85 161 261 263 348 194 154 179
2025/20266.825 434 433 469 1.049 528 218 521 521 1.999 343 218 92
2026/2027431 162 269 0 0 0 0 0 0 0 0 0 0
Totale 10.751