IRIS
GUIDOTTI, LUCA
 Distribuzione geografica
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Continente #
AS - Asia 2.679
NA - Nord America 1.526
EU - Europa 1.317
SA - Sud America 719
AF - Africa 61
OC - Oceania 7
Totale 6.309
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Nazione #
US - Stati Uniti d'America 1.443
SG - Singapore 1.164
CN - Cina 721
BR - Brasile 587
SE - Svezia 544
HK - Hong Kong 407
IT - Italia 226
VN - Vietnam 213
RU - Federazione Russa 136
DE - Germania 127
AR - Argentina 61
GB - Regno Unito 57
FI - Finlandia 44
AT - Austria 41
CA - Canada 39
ID - Indonesia 35
IN - India 34
MX - Messico 32
PL - Polonia 30
EC - Ecuador 25
ZA - Sudafrica 22
BD - Bangladesh 21
NL - Olanda 20
CO - Colombia 19
IQ - Iraq 19
IE - Irlanda 16
ES - Italia 12
FR - Francia 12
GH - Ghana 12
UA - Ucraina 11
TR - Turchia 10
PY - Paraguay 8
AU - Australia 7
CH - Svizzera 7
JP - Giappone 7
CL - Cile 6
MA - Marocco 6
PK - Pakistan 6
VE - Venezuela 6
BE - Belgio 5
IR - Iran 5
RO - Romania 5
SA - Arabia Saudita 5
AE - Emirati Arabi Uniti 4
AL - Albania 4
CZ - Repubblica Ceca 4
KE - Kenya 4
LT - Lituania 4
TW - Taiwan 4
BO - Bolivia 3
IL - Israele 3
JM - Giamaica 3
KZ - Kazakistan 3
MK - Macedonia 3
RS - Serbia 3
UZ - Uzbekistan 3
AO - Angola 2
DO - Repubblica Dominicana 2
EG - Egitto 2
ET - Etiopia 2
HN - Honduras 2
KR - Corea 2
LB - Libano 2
MY - Malesia 2
OM - Oman 2
PH - Filippine 2
SZ - Regno dello Swaziland 2
TN - Tunisia 2
UY - Uruguay 2
YE - Yemen 2
AZ - Azerbaigian 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BG - Bulgaria 1
BW - Botswana 1
CD - Congo 1
CG - Congo 1
CI - Costa d'Avorio 1
DK - Danimarca 1
DZ - Algeria 1
GD - Grenada 1
GY - Guiana 1
KH - Cambogia 1
KN - Saint Kitts e Nevis 1
LV - Lettonia 1
NG - Nigeria 1
PA - Panama 1
PE - Perù 1
PT - Portogallo 1
SK - Slovacchia (Repubblica Slovacca) 1
SN - Senegal 1
TH - Thailandia 1
TT - Trinidad e Tobago 1
Totale 6.309
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Città #
Singapore 449
Hong Kong 404
Ashburn 257
Dallas 232
Shanghai 166
Hefei 158
Lawrence 142
Princeton 142
Beijing 117
Milan 89
Ho Chi Minh City 84
São Paulo 54
Los Angeles 50
New York 48
The Dalles 46
Hanoi 42
Nuremberg 39
Helsinki 35
Boardman 32
Warsaw 27
Munich 22
Denver 21
Moscow 19
Rome 19
Vienna 19
Belo Horizonte 18
Cesano Boscone 17
Dublin 16
Stockholm 16
Montreal 15
Rio de Janeiro 14
Santa Clara 14
London 13
São José dos Campos 13
Accra 12
Amsterdam 11
Guangzhou 11
Manchester 11
Poplar 11
Atlanta 10
Biên Hòa 10
Brooklyn 10
Johannesburg 10
Orem 10
Porto Alegre 10
Brasília 9
Curitiba 9
Mexico City 9
Boston 8
Chennai 8
Haiphong 8
Jiaxing 8
Pune 8
Salvador 8
Da Nang 7
Houston 7
Meda 7
Pelotas 7
Quito 7
San Francisco 7
Shenzhen 7
Tianjin 7
Toronto 7
Xi'an 7
Campinas 6
Fortaleza 6
Ha Long 6
Manaus 6
Querétaro 6
Seattle 6
Thái Nguyên 6
Tokyo 6
Wuxi 6
Baghdad 5
Buenos Aires 5
Chicago 5
Columbus 5
Goiânia 5
Guarulhos 5
Guayaquil 5
Heidelberg 5
Mumbai 5
Phoenix 5
Thái Bình 5
Ancona 4
Bandung 4
Bloomington 4
Bogotá 4
Caracas 4
Colombo 4
Cotia 4
Council Bluffs 4
Durban 4
Erbil 4
Erechim 4
Franca 4
Frankfurt am Main 4
Jakarta 4
Jundiaí 4
La Plata 4
Totale 3.283
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Nome #
Administration of aerosolized SARS-CoV-2 to K18-hACE2 mice uncouples respiratory infection from fatal neuroinvasion 115
Immunobiology and pathogenesis of hepatitis B virus infection 109
COVID-eVax, an electroporated DNA vaccine candidate encoding the SARS-CoV-2 RBD, elicits protective responses in animal models 98
CD4+T cells license Kupffer cells to produce IL-27 and reverse the CD8+T cell dysfunction induced by hepatocellular priming 97
Antibody-independent protection against heterologous SARS-CoV-2 challenge conferred by prior infection or vaccination 94
Discovery and antiviral profile of new sulfamoylbenzamide derivatives as HBV capsid assembly modulators 81
Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming 81
Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. 77
Therapeutic potential of co-signaling receptor modulation in hepatitis B 76
Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming 73
Pathogen-specific B-cell receptors drive chronic lymphocytic leukemia by light-chain-dependent cross-reaction with autoantigens 66
Inflammatory monocytes hinder antiviral B cell responses 66
Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice 66
Arenaviral infection causes bleeding in mice due to reduced serotonin release from platelets 65
Bone marrow as an alternative site for islet transplantation 65
Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection 64
Nirmatrelvir treatment of SARS-CoV-2-infected mice blunts antiviral adaptive immune responses 63
Immunosurveillance of the liver by intravascular effector CD8+ T cells 63
T-cell-derived IFN-γ suppresses T follicular helper cell differentiation and antibody responses 61
Antiplatelet drug therapy moderates immune-mediated liver disease and inhibits viral clearance in mice infected with a replication-deficient adenovirus 61
Anti-platelet therapy in the prevention of hepatitis B virus-associated hepatocellular carcinoma 61
A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen 58
Role of CCL2/MCP-1 in islet transplantation 58
Effector CD8+T cell-derived interleukin-10 enhances acute liver immunopathology 57
Group 1 ILCs regulate T cell-mediated liver immunopathology by controlling local IL-2 availability 57
Bisphosphonates Target B Cells to Enhance Humoral Immune Responses 56
Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans 54
A two hit model of CTL killing in vivo 53
Extracellular HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV pathogenesis 53
Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes 52
A global scientific strategy to cure hepatitis B 52
Preclinical assessment of capsid assembly modulators (CAMs) of varying potency revealed a novel class of picomolar-acting CAMs inducing neither significant HBcAg cytoplasmic retention nor adverse interactions with HBcAg-specific adaptive immunity 52
Breaking tolerance leads to autoantibody production but not autoimmune liver-disease in hepatitis-B virus envelope transgenic mice 51
Immunological insights in the treatment of chronic hepatitis B 51
Bone marrow as an alternative site for islet transplantation 50
Cytotoxic T-lymphocytes inhibit hepatitis-B virus gene-expression by a noncytolytic mechanism in transgenic mice 50
Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 48
Altered helper T lymphocyte (HTL) function associated with chronic HBV infection and its role in response to therapeutic vaccination in humans 48
Platelets mediate cytotoxic T lymphocyte-induced liver damage 48
Protective and Pathogenic T Cell Responses to Virus Infections 48
Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier 46
Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis 46
CD4+ T cells license Kupffer cells to reverse CD8+ T cell dysfunction induced by hepatocellular priming 45
Analysis of a successful immune response against HBV 45
Activated intrahepatic antigen presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice 45
Modulation of Early Inflammatory Reactions to Promote Engraftment and Function of Transplanted Pancreatic Islets in Autoimmune Diabetes 45
Inhibitors of hepatitis B virus 45
Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4(+) T Cell Help 44
MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs 44
Pathogenesis of hepatitis B virus in transgenic mice 44
Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation 44
Editorial overview: Viral pathogenesis 42
The COP9 signalosome is a repressor of replicative stress responses and polyploidization in the regenerating liver 42
Microcirculation in the murine liver: a computational fluid dynamic model based on 3D reconstruction from in vivo microscopy 42
Subcapsular sinus macrophages prevent CNS invasion on peripheral infection with a neurotropic virus 41
Platelets mediate cytotoxic T lymphocyte-induced liver damage 41
Cyclic inhibitors of hepatitis B virus 41
Naive HIV/HCV-coinfected patients have higher intrahepatic pro-inflammatory cytokines than coinfected patients treated with antiretroviral therapy 40
In vivo flow mapping in complex vessel networks by single image correlation 40
The transgenic mouse model of hepatitis B virus infection 40
Mouse models of hepatitis B virus pathogenesis 40
IFN gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment 40
HBV pathogenesis in animal models: Recent advances on the role of platelets 39
Platelets mediate CTL-induced immunopathology in the liver 39
Cytokine-mediated control of viral infections 39
Cytotoxic T-lymphocytes can clear hepatitis-B virus from the hepatocyte without killing the cell 39
Update of the statements on biology and clinical impact of occult hepatitis B virus infection 38
Is it time to recommend low-dose aspirin treatment for the prevention of hepatocellular carcinoma? 38
Pathogenetic and antiviral immune responses against hepatitis B virus 37
The optimization of helper T lymphocyte (HTL) function in vaccine development 37
Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site 37
Kupffer cells reduce liver immunopathology 37
TIE2-expressing monocytes regulate revascularisation of the ischaemic limb 37
HBV Immunopathogenesis 37
Tricyclic inhibitors of hepatitis B virus 37
Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes 36
CTL access to tissue antigen is restricted in-vivo 36
Mechanisms of class-I restricted immunopathology - a transgenic mouse model of fulminant-hepatitis 36
Nuclear covalently closed circular viral genomic DNA in the liver of hepatocyte nuclear factor 1 alpha-null hepatitis B virus transgenic mice 36
Hepatitis C virus core and E2 protein expression in transgenic mice 36
Hepatitis-B virus nucleocapsid particles do not cross the hepatocyte nuclear-membrane in transgenic mice 36
The hepatitis B virus X protein transactivates viral core gene expression in vivo 36
Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic mice 36
T helper-1 lymphocytes mediate liver disease in hepatitis B virus transgenic mice 35
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes 35
Host-virus interactions during malaria infection in hepatitis B virus transgenic mice 35
Hepatitis B virus RNA-binding proteins associated with cytokine-induced clearance of viral RNA from the liver of transgenic mice 35
High-level hepatitis-B virus-replication in transgenic mice 34
Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich Syndrome patients 34
Class-I restricted cytotoxic T-lymphocytes are directly cytopathic for their target-cells in-vivo 34
Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus 33
Cytotoxic T-lymphocyte mediated regulation of hepatitis-B virus gene-expression in-vivo 33
On the role of platelets in the pathogenesis of viral hepatitis 33
Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis 33
Hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice 33
Effector CD8 T cell trafficking within the liver 33
Thymic tolerance to only one viral protein reduces lymphocytic choriomeningitis virus-induced immunopathology and increases survival in perforin-deficient mice 33
Liver gene expression associated with the inhibition of HBV replication or transcription 32
T-cell responses and intrahepatic cytokine profiles in HBV- and HCV-infected chimpanzees 32
Different intrahepatic cytoknie priles during acure HBV and HCV infection in the same chimpanzees 31
Totale 4.887
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Categoria #
all - tutte 53.783
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 53.783
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/202110 0 0 0 0 0 3 5 0 0 2 0 0
2021/2022121 0 0 0 57 2 0 6 3 5 7 5 36
2022/2023846 302 200 62 2 13 118 21 78 31 1 4 14
2023/2024419 22 16 59 114 29 37 13 29 4 10 31 55
2024/20252.003 264 20 15 59 85 161 261 263 348 194 154 179
2025/20262.952 434 433 469 1.049 528 39 0 0 0 0 0 0
Totale 6.447